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        New Message Board Archives >> Medications, Treatments, Therapies 2005 >> Imitrex SQ: reduced dosing
        
(Message started by: Bob_Johnson on Aug 23^rd, 2005, 9:18am)

Title: Imitrex SQ: reduced dosing
Post by Bob_Johnson on Aug 23^rd, 2005, 9:18am

Headache. 2005 Sep;45(8):1069-72.

Treatment of Cluster Headache Attacks With Less Than 6 mg Subcutaneous Sumatriptan.

Gregor N, Schlesiger C, Akova-Ozturk E, Kraemer C, Husstedt IW, Evers S.

Background.-Subcutaneous (SQ) sumatriptan 6 mg is effective in the treatment of acute cluster headache attacks. However, patients sometimes benefit from a dose less than 6 mg. Objective.-Therefore, we designed a prospective open study to evaluate how many patients benefit from a dose less than 6 mg SQ sumatriptan. Methods.-We enrolled 81 consecutive patients with cluster headache and recorded their use of SQ sumatriptan and oxygen. Patients regularly using SQ sumatriptan 6 mg were advised to treat attacks with doses less than 6 mg and with oxygen. Efficacy and side effects of the different treatment options (6 mg, 3 mg, 2 mg, and oxygen) were evaluated. Results.-As a result, 74% of the patients using SQ sumatriptan 3 mg showed efficacy and 89% reported efficacy after 2 mg. Seventy-nine percent reported side effects after the use of SQ sumatriptan 6 mg (29% severe side effects). After the use of 2 mg SQ sumatriptan, only 50% of the patients reported side effects, none of these were classified as severe. Patients' preference was 41% for 6 mg sumatriptan, 28% for doses less than 6 mg, and 31% for oxygen. Conclusions.-We conclude that sumatriptan in doses less than 6 mg can be effective in the acute treatment of cluster headache attacks. We suggest that patients should have experience in their individual efficacy of sumatriptan doses less than 6 mg. (Headache 2005;45:1069-1072).

PMID: 16109122

Title: Re: Imitrex SQ: reduced dosing
Post by jcmquix on Aug 23^rd, 2005, 12:25pm

Great Report Bob_Johnson !!!!

This really works !!!!!

PFDAN to ALL !!!
Charlie

Title: Re: Imitrex SQ: reduced dosing
Post by LasVegas on Aug 23^rd, 2005, 10:56pm

Good post!