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Kevin_M
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Re: 02 Preventative?
« Reply #25 on: May 1st, 2008, 10:47pm »
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on May 1st, 2008, 7:50pm, Jonny wrote:
After a week of this...

 
Life in the unprevented lane, a very tough route.  Keep that seat belt on 'til you get to the appointment.  
 
You remind me of that soldier that left the patrol boat to pick mangos in "Apocalyse Now".  He comes face to face with a tiger then gets back to the boat muttering, never leave the boat, never leave the boat.
 
Never run out of verap, buddy.   Best to ya, hang in.
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Re: 02 Preventative?
« Reply #26 on: May 3rd, 2008, 7:33pm »
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on May 1st, 2008, 2:21am, Batch wrote:
Jonny,
 
Here's my hypothesis...  Acidosis is a vasodilator and as such, makes us more susceptible to cluster headache attacks.  By raising the arterial bloodstream pH above neutral (pH =7.4) to say 7.6 to 7.8, we will experience a reduction in the frequency and intensity of our cluster headache attacks...  And, if we do have an attack with an elevated pH, the attack will be easy to abort with oxygen therapy or imitrex.
 
 
3.  Follow the suggested dietary guide in the acid-alkaline balance link above to raise your pH to at least 7.5 or a little higher at bedtime.  This will likely take a few days so don’t expect a big change in pH right away.  V/R, Batch  
 

 
 
Hi Pete,
 
Thank you for posting your hypothesis which is very interesting. However, I have a few questions to ask of you though.
 
1- Arterial pH of 7.6 or more is considered dangerous to health, at that level the person can be delirious, having muscular jerks or even seizures as well as increased risk of angina and possible coronary infarction. In hospital, patients with arterial pH of 7.6 or more are treated urgently with haemofiltration or haemodialysis.  
 
http://www.merck.com/mmpe/sec12/ch157/ch157d.html
 
2- Metabolic alkalosis with pH more than 7.44 can only be maintained long term ( more than 6 hours ) when the kidneys have been compromised, with impairment of HCO3 excretion, otherwise the body antidiuretic system will kick in and compensation will occur. On top of that, respiratory rate will automatically slow down to induce respiratory acidosis to neutralise the pH. You cant maintain a very high arterial pH naturally in a healthy body.
 
http://en.wikipedia.org/wiki/Metabolic_alkalosis
 
3- In vivo and in vitro, experiment on rats and rabbits cerebral blood flow indicate that metabolic alkalosis needs to be at least at pH 7.5 to have any vasoconstricting effect. In fact, pH needs to be as high as 7.8 to achieve vasoconstriction of all the smooth muscle cells in the arterial wall. However, at this level the person would be severely ill. pH 8 or higher can cause death.  
 
http://ajpheart.physiology.org/cgi/content/full/283/6/H2169
 
4- Testing arterial pH level through saliva and urine test strips are not very accurate. Their accuracy level is between 0.2 and 0.5. Testing the urine will give you the urine pH, not arterial pH and therefore is often a lot more acidic. Testing saliva will give you the saliva pH, not arterial pH either. It is used only as an indication, there isnt a formula that you can use to convert these numbers to an arterial reading. To get accurate arterial pH level one has to do blood gas ie take blood from your artery and send it to the lab.
 
There are many factors that can affect the pH levels of urine or saliva, including renal function, physical activities, food, drinks and even food stuck in between your teeth and skin contamination. You have to read the value by looking at the colour change and depending on your eyesight and whether or not you may have colour blindness this can greatly affect what number you come up with.
 
[url] http://www.indigo.com/test-strips/gph-test-strips/ph-paper-5.5-8.html[/url]
 
 
Therefore I am not quite sure how we can implement/test your theory in practice?  
 
I would be grateful if you can help with further information.
 
Thanks and all the best wishes.  
 
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Re: 02 Preventative?
« Reply #27 on: May 4th, 2008, 12:21am »
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on May 1st, 2008, 9:22pm, Jonny wrote:

 
I dont think im cut out for this episodic shit!  
 

 
 laugh
 
 
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Re: 02 Preventative?
« Reply #28 on: May 5th, 2008, 3:30am »
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Sorry to hear your hurtin & I agree being chronic is much easier to handle.
 
Something that may be worth a try; on my last high cycle I found that if I took an Imigran tablet 50 mg (sumatriptan as succinate)while aborting the current hit with o2 I could get 6 -8 hours before I would get the next hit & would actually be able to get some sleep in between.
Anything is worth a try.
 
 
Cheers
Barry
« Last Edit: May 5th, 2008, 7:07am by Barry_T_Coles » IP Logged

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Re: 02 Preventative?
« Reply #29 on: May 5th, 2008, 2:21pm »
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Damn, Jonny!
 
I'm so sorry you are going thru this again.  
 
You were chronic for a lifetime, then had blessed months of pain free time.
 
My heart hurts for you.
 
I don't know what I can do to help you, but God as my witness, I will be looking.
 
Sandy
 
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Re: 02 Preventative?
« Reply #30 on: May 5th, 2008, 6:05pm »
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hope it passes soon. breath deep, stay hydrated and eat fish. andrew.
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