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Cluster Headache Help and Support >> Medications, Treatments, Therapies >> Chronic Cluster--Warfarin treatment
(Message started by: Bob_Johnson on Feb 6th, 2006, 1:17pm)

Title: Chronic Cluster--Warfarin treatment
Post by Bob_Johnson on Feb 6th, 2006, 1:17pm
This is about the second article on this topic which I've posted in the last few years. It would be interesting if we could see some reports from folks who may have tried this approach.
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J Headache Pain. 2005 Oct;6(5):417-9. Epub 2005 Aug 1. Related Articles, Links  


Warfarin as a therapeutic option in the control of chronic cluster headache: a report of three cases.

Kowacs PA, Piovesan EJ, de Campos RW, Lange MC, Zetola VF, Werneck LC.

Headache Section, Neurology Division, Internal Medicine Department, Hospital de Clinicas, Universidade Federal do Parana, Rua General Carneiro 181/1236, 80060-900 Curitiba, Brazil. cefaleia@hc.ufpr.br

Chronic cluster headache remains refractory to medical therapy in at least 30% of those who suffer from this condition. The lack of alternative medical therapies that are as effective as, or more effective than, lithium carbonate makes new therapies necessary for this highly disabling condition. Based on a previous report, we gave oral anticoagulants to three patients with chronic cluster headache. Two of them remained cluster headache-free while taking warfarin. In the third patient, the use of warfarin for three weeks initially increased the frequency and intensity of cluster headache attacks but subsequently induced a prolonged remission. In spite of the paucity of data available, oral anticoagulation appears to be a promising therapy for chronic cluster headache.

PMID: 16362716



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