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   Author  Topic: Clusters/Harvard Study appear in New Scientist  (Read 322 times)
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Clusters/Harvard Study appear in New Scientist
« on: Feb 24th, 2005, 1:10am »
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Here are some key paragraphs from a long article in this coming Saturday's edition of New Scientist on the resurgence of interest in psychedelics.  
 
Psychedelic medicine: Mind bending, health giving  
 
 
    * 26 February 2005  
    * From New Scientist Print Edition.  
    * John Horgan is a freelance science writer based in Garrison, New  
York. His latest book, Rational Mysticism (Mariner Books), was  
published in paperback last year  
 
 
JOHN HALPERN clearly remembers what made him change his mind about  
psychedelic drugs. It was the early 1990s and the young medical  
student at a hospital in Brooklyn, New York, was getting frustrated  
that he could not do more to help the alcoholics and addicts in his  
care. He sounded off to an older psychiatrist, who mentioned that LSD  
and related drugs had once been considered promising treatments for  
addiction. "I was so fascinated that I did all this research," Halpern  
recalls. "I was reading all these papers from the 60s and going, whoa,  
wait a minute! How come nobody's talking about this?"  
 
 
More than a decade later, Halpern is now an associate director of  
substance abuse research at Harvard University's McLean Hospital and  
is at the forefront of a revival of research into psychedelic  
medicine. He recently received approval from the US Food and Drug  
Administration (FDA) to give late-stage cancer patients the  
psychedelic drug MDMA, also known as ecstasy. He is also laying the  
groundwork for testing LSD as a treatment for dreaded super-migraines  
known as cluster headaches.  
 
 
And Halpern is not alone. Clinical trials of psychedelic drugs are  
planned or under way at numerous centres around the world for  
conditions ranging from anxiety to alcoholism. It may not be long  
before doctors are legally prescribing hallucinogens for the first  
time in decades. "There are medicines here that have been overlooked,  
that are fundamentally valuable," says Halpern.  
 
 
For now, however, Halpern isn't planning to pursue addiction therapy.  
He is more interested in another medical use for LSD and psilocybin:  
treating a debilitating condition known as cluster headaches. These  
attacks appear to be caused by swelling of blood vessels in the brain  
and are worse than migraines. Sufferers say the pain exceeds that of  
passing a kidney stone or giving birth without anaesthetics. They  
affect about 3 in every 1000 people sporadically, and 1 in 10,000  
chronically. "There's a tremendous potential need for this," says  
Halpern, who investigated the problem after being approached by a  
patient group.  
 
 
Many patients get little or no relief from painkillers, but some claim  
that small doses of LSD or psilocybin can alleviate the headaches and  
even prevent them from occurring. Halpern was intrigued; LSD is  
chemically related to ergot, a naturally occurring compound that  
constricts blood vessels, and the derivatives ergotamine and  
methysergide are commonly prescribed for migraines.  
 
 
Halpern and his Harvard colleague Andrew Sewell are now gathering  
evidence to persuade licensing officials - and themselves - that LSD  
and psilocybin merit a clinical trial. Sewell has gathered more than  
60 testimonials from cluster headache sufferers who have treated  
themselves with LSD or psilocybin.  
 
 
Read the entire article here:  
http://www.newscientist.com/channel/health/mg18524881.400  
The rest is pretty interesting too.  
 
Bobw
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Re: Clusters/Harvard Study appear in New Scientist
« Reply #1 on: Feb 24th, 2005, 2:05am »
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Interesting info, Bob
 
Thanks!!
 
Jean
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Re: Clusters/Harvard Study appear in New Scientist
« Reply #2 on: Feb 24th, 2005, 5:16am »
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Hi Bobw,
 
Thanks for sharing this exciting article. Wouldn't it be great if this proven therapy were to finally become legal? Hope this is the beginning.
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