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Daily Chat >> General Posts >> nimodepine? http://www.clusterheadaches.com/cgi-bin/yabb2/YaBB.pl?num=1261020041 Message started by atsea on Dec 16th, 2009 at 10:20pm |
Title: nimodepine? Post by atsea on Dec 16th, 2009 at 10:20pm
anyone ever used nimodepine as an abortive? how about trexamet? i know its just a imitrex derivitive, but, i hear first hand it is more effective and faster than the imitrex subQ. starting verapamil as a prophylactic. 360 mg/day as well.
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Title: Re: nimodepine? Post by deltadarlin on Dec 17th, 2009 at 8:00am
I've never heard of using a calcium channel blocker as an abortive. Most CCBs are used as preventatives, not abortives.
As to treximet. Don't know about ch, but I was using treximet for migraines, long before it was even developed (I'd take Imitrex and an aleve at the same time). Didn't work any better. Treximet is just a fancy name for a combo of aleve and Imitrex (moer expensive because there is no generic equivalent). |
Title: Re: nimodepine? Post by atsea on Dec 17th, 2009 at 8:42am
its apparently a very swift and powerful does of CCB. you bite the liquid filled capsule with your teeth suck out the goodness and swallow it. its suppoed to stop an attack dead in its tracks
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Title: Re: nimodepine? Post by deltadarlin on Dec 17th, 2009 at 8:45am
Post this on the medications board, you'll get more info there.
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Title: Re: nimodepine? Post by Marc on Dec 17th, 2009 at 8:54am atsea wrote on Dec 17th, 2009 at 8:42am:
What is your source of info on this? Marc |
Title: Re: nimodepine? Post by Marc on Dec 17th, 2009 at 9:55am
In some listings, Verapamil is also listed as a vasodilator - as we know, it also a CCB - which are not true dilators. They function by "relaxing" the constricting/dilating action of smooth muscle tissue.
Marc |
Title: Re: nimodepine? Post by atsea on Dec 17th, 2009 at 11:59am
the nimodepine treatment was cited in a HEADACHE JOURNAL article written by a renowned MAYO clinic neurologist.
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Title: Re: nimodepine? Post by Brew on Dec 17th, 2009 at 12:06pm atsea wrote on Dec 17th, 2009 at 11:59am:
Which issue, what author? |
Title: Re: nimodepine? Post by atsea on Dec 17th, 2009 at 9:32pm
damn. i'll have to find the issue again. i though i bookmarked it. it was authored my robert ford?
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Title: Re: nimodepine? Post by Redd on Dec 17th, 2009 at 10:18pm Marc wrote on Dec 17th, 2009 at 9:55am:
True, but Verap. isn't used as an abortive agent either. I guess I just cringe at the notion of a vasodilator as a Ch abortive agent. Sort of like prescribing nitroglycerin as an abortive....... |
Title: Re: nimodepine? Post by Bob P on Dec 18th, 2009 at 7:37am |
Title: Re: nimodepine? Post by Marc on Dec 18th, 2009 at 9:38am Redd wrote on Dec 17th, 2009 at 10:18pm:
I see what you're saying Pegg. I was only trying to say that I don't think it's actually a vasodialtor, but a "relaxer" like my girlfriend Vera. Aside from all of that: I know this goes against the grain of the general thinking around here, but I'm not convinced that vasodialtion/constriction is the key. Verapamil is believed by some to act on the hypothalamus to help us in lieu of it's vascular effect only. Same with the Triptans. High flow O2 is my best friend, but I can't help wonder if it's effect is more far reaching than just constriction. I'd have to dig up the articles, but there enough researchers saying this to give me pause. Nitro is an exception that I can't explain, but there is still a lot that we don't know. Cat has linked to a plethora of articles on this subject several times. Marc |
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