New CH.com Forum - Print Page

New CH.com Forum
http://www.clusterheadaches.com/cgi-bin/yabb2/YaBB.pl Cluster Headache Help and Support >> Medications, Treatments, Therapies >> Frova as a prevent http://www.clusterheadaches.com/cgi-bin/yabb2/YaBB.pl?num=1294230199 Message started by Bob P on Jan 5^th, 2011 at 7:23am

Title: Frova as a prevent
Post by Bob P on Jan 5^th, 2011 at 7:23am

Quote:

Results.— The study was prematurely discontinued after 13 months and enrollment of 11, instead of the planned 80 patients, by the sponsor due to infeasibility. Recruitment was slow and each of the patients included conducted major protocol violations. The differences in the primary and secondary endpoints were not significant.

Shame on us.

Title: Re: Frova as a prevent
Post by cluster on Jan 15^th, 2011 at 11:58am

They were after episodic patients and didn't let me participate, 'cause I'm chronic.

See

START PRINTPAGEMultimedia File Viewing and Clickable Links are available for Registered Members only!! You need to

END PRINTPAGE

for more details.

Title: Re: Frova as a prevent
Post by Batch on Jan 15^th, 2011 at 3:42pm

It's probably just as well they cnx'd this study. Triptans are a lot more invasive than the pharma's or much of the literature lets on. Using any triptan too long can do a number on the heart.

I know I sound like a stuck record, but oxygen therapy has no invasive or lasting side effects compared to the triptans. It's far less expensive and if used at flow rates that support hyperventilation, ≥25 liters/minute, it's capable of producing aborts just as fast as sumatriptan injections with greater efficacy.

Take care,

V/R, Batch

Title: Re: Frova as a prevent
Post by Brew on Jan 15^th, 2011 at 4:39pm

However we don't want anybody to confuse the best known abortive with a preventative. Completely different strategies.