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Cluster Headache Help and Support >> Medications,  Treatments,  Therapies >> LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
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Message started by elliott on Nov 20th, 2012 at 10:13pm

Title: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 20th, 2012 at 10:13pm
My name is Dr. Elliott.  I have a Phd. in kicking ass and Googling shit.  This thread will be for 2 years, 730 days.  Like every good scientist, I will be experimenting on myself (lol, some sarcasm to lighten the mood) and whoever else is willing to do whatever it takes to be cluster free for the rest of their lives.  The goal is to reach 2 years with absolutely no clusters, thereby concluding my "research" and cementing my finds, in hopes of being the man that shuts the door on CH and laughing in its face.

Hypothesis:  CH are caused by dopamine overdose/dopamine receptor overload.  Dopamine plays a part in the hypothalamus (active region of the brain during CH attacks?) which controls the Endocrine system (trigeminal nerve, the one that fucks up your day).  CH suffers are genetically susceptible to one adverse effect of "dopamine syndrome":  Cluster Headaches. 

Through a "rebooting" of the brains internal wiring, dopamine receptors can heal themselves of the damage caused by overuse or overstimulation.

CH suffers, being largely male, have overstimulated these dopamine receptors through masturbation. (RED FLAG, keep reading though).  Our generation at least, has been able to constantly increase the limit cap of our dopamine receptors by finding newer and newer untapped dopamine banks due to the Information Age.  Porn is always ready to give the dopamine receptors what they need, when they need it, something that may seem convenient, but is pumping the endocrine system with so much that the overwhelming amount of "dopamine damage control" loses its fucking mind when the seasons change and daylights savings occurs, resetting the hypothalamus, triggering a daisy chain effect.


The Trials:  Give up porn, give up masturbation.  Sex is ok.
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Who's in?


I am currently on day 5.  First Cluster Free day of my cycle.  I have a very strange shadow going on that started dead center of my forehead, and is moving left.  Just a moment ago it shut down my left nostril.  My clusters occur on the right side.

There is something very strange going on in my brain.  I feel it really is being rewired.  I hope this doesn't bite me in the ass and I end up having one tomorrow.

Will update tomorrow, and every day after.  I will find the cure for us, if not through this, somehow.


Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Potter on Nov 20th, 2012 at 10:23pm
Yer shittin me.

    Potter


Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 20th, 2012 at 10:23pm
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Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 20th, 2012 at 10:29pm
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I realize I look very stupid, and I don't really know what order to present everything I know about CH in, but I've been researching it for a long time.  The circadian rhythm, trigeminal nerve,  hypothalamus, all related to dopamine.  A google search for "porn related ED" will bring you thousands of new findings that you may not want to see.

There's so much information I want to present, but I'm a friggin high school student who's been in the military for 4 years.  Sorry.

At best, my theory works and CH is cured.  At the worst...well I've wasted your time, but just follow my cluster log and we'll see together.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Brew on Nov 20th, 2012 at 10:29pm
Porn and masturbation as the primary cause of CH.

Maybe I HAVEN'T heard it all yet.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by jon019 on Nov 20th, 2012 at 10:56pm
starve 'em.........................................

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Potter on Nov 20th, 2012 at 10:58pm
Bullshit.

  Potter

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 20th, 2012 at 10:59pm
*shrug*

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Potter on Nov 20th, 2012 at 11:05pm
I thought you had found your cure at Dunkin Donuts last week?

      Potter

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 20th, 2012 at 11:18pm
The massive levels of caffeine in those Dunkacinnos are THE definition of temporary fix

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 20th, 2012 at 11:34pm
Mid level shadow, on my LEFT side. 

No forehead anymore, it has literally moved across my fucking face.  I'm gonna take a shot of imitrex and hit the sack.  Tomorrow is a new day gents, remember this is day 5 of "abstinence".

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by AussieBrian on Nov 20th, 2012 at 11:37pm
I'm fully in favour of the trial while no guinea pigs are hurt or stressed.

I like me dinner unbruised.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 21st, 2012 at 9:03am

AussieBrian wrote on Nov 20th, 2012 at 11:37pm:
I'm fully in favour of the trial while no guinea pigs are hurt or stressed.

I like me dinner unbruised.


Lol

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Batch on Nov 21st, 2012 at 10:09am
Sam,

God loves a Marine...  and thank you for your service...

I also appreciate your Devil Dog approach to finding a way to control your cluster headaches...  That said, I think you've got target fixation on the wrong nuclear receptor...

Google VDR, VDRE, 25(OH)D and 1,25(OH)2D for starters...  then ask your Unit MO for a lab test for 25(OH)D... 

Odds are your serum concentration of 25(OH)D is below the normal reference range of 30 to 100 ng/mL... 

Please keep us posted on the results...

Semper Fi

V/R, Batch

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 21st, 2012 at 10:24am
Thanks Batch, and I will do that.

I recently got a "complete" blood test done and nothing was found at all, but I will mention everything you said.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Potter on Nov 21st, 2012 at 10:36am
If whackin it was the cause of ch wouldn't every male have them in proportion to the number of times whacked?  Thusly some would be chronic and some episodic.  But everyone would have them.

             Potter

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Zeitgeist on Nov 21st, 2012 at 11:11am
I for one like the hypothesis.  Both funny and interesting.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Batch on Nov 21st, 2012 at 11:18am
Sam,

The lab test for 25(OH)D is in the endocrine diagnostic panel so will not show up in a CBC/Chemistry panel. 

You'll need to ask for the 25(OH)D diagnostic lab test... and don't take "No" for an answer... 

The odds are you're vitamin D3 deficient, i.e., a serum concentration of 25(OH)D less than 30 ng/mL, and that deficiency is likely contributing to your episodic cluster headaches.

CH'ers who have gone pain free while taking the anti-inflammatory regimen with 10,000 IU/day or more vitamin D3 and then gone in for the 25(OH)D lab test have all reported being in a range of 60 to 110 ng/mL.

See the following two links for details:

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Shoot me a PM if you have any questions.

Take care.

Semper Fi

V/R, Batch

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by pattik on Nov 21st, 2012 at 1:31pm
I love your creative theory.  But now let's figure out how women CH'ers play into this (I know, women don't get CH).  [smiley=grin2.gif] We may not watch as much porn as guys, but there's always shopping and chocolate.  This experiment will be a little difficult setting up the parameters.  Still, I applaud your ingenuity!

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Brew on Nov 21st, 2012 at 2:52pm

pattik wrote on Nov 21st, 2012 at 1:31pm:
I love your creative theory.  But now let's figure out how women CH'ers play into this (I know, women don't get CH).  [smiley=grin2.gif] We may not watch as much porn as guys, but there's always shopping and chocolate.  This experiment will be a little difficult setting up the parameters.  Still, I applaud your ingenuity!

Since real, honest-to-goodness sex is allowed within the confines of this theory, it must be that the wimmens aren't eating real, honest-to-goodness chocolate (Baby Ruth vs. Ghirardelli). Or doing real, honest-to-goodness shopping (Walmart online vs. Sax Fifth Avenue in person).

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 21st, 2012 at 4:28pm

Potter wrote on Nov 21st, 2012 at 10:36am:
If whackin it was the cause of ch wouldn't every male have them in proportion to the number of times whacked?  Thusly some would be chronic and some episodic.  But everyone would have them.

             Potter


Well the idea is that CH suffers are genetically prone to this.  I'm trying to connect the dots.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 21st, 2012 at 4:31pm

pattik wrote on Nov 21st, 2012 at 1:31pm:
I love your creative theory.  But now let's figure out how women CH'ers play into this (I know, women don't get CH).  [smiley=grin2.gif] We may not watch as much porn as guys, but there's always shopping and chocolate.  This experiment will be a little difficult setting up the parameters.  Still, I applaud your ingenuity!



This is where my theory falls short and I chalk it up to either misdiagnosis of severe migraines, or perhaps damaged dopamine receptors from birth.  Sorry ladies but my theory fails you.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 21st, 2012 at 4:31pm

Zeitgeist wrote on Nov 21st, 2012 at 11:11am:
I for one like the hypothesis.  Both funny and interesting.



Thanks

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 21st, 2012 at 4:38pm
Batch -  I will ask for this test ASAP, unfortunately my entire unit is out for the holiday.

UPDATE:  Last night I gave myself an imitrex injection around midnight for the odd Left-side cluster headache I was having.

Woke up at 6:30 for formation, had breakfast and was back in bed by 10:30.

From 10:30 AM to 4:30 I slept.  I woke up to a CH....shadow.  The ones that wake me up are usually full blown attacks.  Gave myself a shot if imitrex and here I am.



My usual attacks occur at 10 AM and 10 PM.  The ones that wake me up being 2-4 in the morning, and OCCASIONAL attacks around 2 PM.


BOTTOM LINE: My frequency of attacks is down.  My intensity of attacks is down.  :D

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Batch on Nov 21st, 2012 at 6:47pm
Sam,

Good news...  Your cycle may be ending...

Run down to the PX or Minni Mart and pick up some 5,000 IU vitamin D3 gel caps, some Citracal Plus™ calcium citrate tablets formulated with magnesium and zinc and some Nature Made Omega 3 Fish Oil gel caps.  If they don't carry them the Food Lion in Jacksonville should have them.

If you take two of each with the biggest meal of the day... I'll wager your CH cycle will end even faster...

Take care and have a Happy Thanksgiving...

Semper Fi

V/R, Batch

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 21st, 2012 at 8:55pm
Thank you Batch, you too.

I have plenty of Imitrex injections to last me and I'm trying to eliminate as many variables as possible.  This cycle started about 3 weeks ago, the fact that its ending now is very odd.  I will try to continue the original experiment with as few variables as possible and use the injections as a backup.  I'm willing to wager that I will be completely off my cycle by this time next week.  8-)

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Zeitgeist on Nov 22nd, 2012 at 7:14am
elliott - The big question is of course - why then aren't all male clusterheads also blind?

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by wimsey1 on Nov 22nd, 2012 at 8:45am
It's funny, in all ways, but does anyone else recall the threads where masturbation was touted as a CH cure? Or abortive. That one went roundy round for quite some time. And the poster was adamant about it. As is Elliot. Can't be both though and I will say what was said then: when I'm in cycle, and on high doses of verapamil, the last thing I'm interested in is sex, or autosex, or tv porn. I just want the PAIN TO GO AWAYYY. blessings. lance

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 22nd, 2012 at 6:28pm
Guys I am almost 100% sure that this is the cause.

To aid in a experiment, I just tried to achieve the fully erect state of happiness and take measurements.  To get this, pulled up a favorite video.  As soon as I got my numbers, I blue balled myself (a total of maybe 30 seconds to do all of this).  As soon as I tricked my brain like that, bam, shadow.

This is the answer guys.  Want to rid yourself of CH?  Stop tuggin, especially to porn.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 23rd, 2012 at 11:09am
Also, as far as the Vitamin D3 working:

Does vitamin D play any role in dopamine?

Active vitamin D plays a role in the formation of dopamine by its effects on the enzyme tyrosine hydroxylase needed to produce dopamine.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Bob Johnson on Nov 23rd, 2012 at 12:15pm
And there are a good many more reports to be had.....




6.Neurologist. 2002 Sep;8(5):279-89.
Causes and management of thunderclap headache: a comprehensive review.
Linn FH, Wijdicks EF.
SourceDepartment of Neurology, Central Military Hospital/University Medical Center, Utrecht, the Netherlands. f.h.h.linn@neuro.azu.nl

Abstract
BACKGROUND: Thunderclap headache (or sudden severe headache) is an uncommon type of headache. Recognition and accurate diagnosis of this headache are important, because there is often a serious underlying brain disorder.

SUMMARY: In this article, causes and management of thunderclap headache are discussed. In the primary care setting, there is a serious cause in one third of patients, but in the hospital setting, up to two thirds of patients have a serious underlying brain disorder. Clues in history and physical examination can point to a possible serious underlying cause of thunderclap headache, such as subarachnoid hemorrhage, intracranial hematoma, or cerebral venous thrombosis. The remaining patients with thunderclap headache, however, have a primary headache disorder, such as migraine or (less frequently) tension headache with an unusual sudden onset, exertional headache, coital headache, cough headache, or CLUSTER HEADACHE. The concept of thunderclap headache as a distinct clinical entity is discussed, with implications for its evaluation. Present radiological techniques are reviewed with regard to their diagnostic utility in detecting a serious brain disorder.

CONCLUSIONS: Thunderclap headache is an uncommon type of headache, and a serious underlying cause should be excluded.

PMID:12803675
=============================
Zh Nevrol Psikhiatr Im S S Korsakova. 2003;103(10):21-5.
[Headache caused by sexual activity].
[Article in Russian]
Ekusheva EV, Filatova EG.
Abstract
Headache caused by sexual activity, or coital headache, is included in International headache classification (1988). The paper presents 19 cases (15 males, 4 females, mean age 34 years) examined by the authors. In 58% of the cases, headache developed before orgasm, in 26%--during orgasm and in 16%--after it. Duration of severe headache was from several to 15 min and of moderate one--up to 7 h. In total, disease lasted from 1 week to 8 years. Focal neurological symptoms were
==========================
Headache. 2004 Mar;44(3):244-8.
Cerebral vasospasm and headache during sexual intercourse and masturbatory orgasms.
Valença MM, Valença LP, Bordini CA, da Silva WF, Leite JP, Antunes-Rodrigues J, Speciali JG.
SourceDivision of Neurology and Neurosurgery, Department of Neuropsychiatry, CCS, Federal University of Pernambuco, Recife, PE, Brazil.

Abstract
BACKGROUND: The pathophysiology of the explosive type of headache associated with sexual activity is not completely understood. Five reported cases of patients with thunderclap headache, precipitated by sexual activity, in association with concomitant cerebral arterial narrowing, were found in the literature.
===============
3.Ginekol Pol. 2005 Dec;76(12):995-9.
[Primary headache associated with sexual activity].
[Article in Polish]
Domitrz I.
SourceKlinika Neurologii, Akademia Medyczna, Warszawa. domitrz@amwaw.edu.pl

Abstract
Benign coital headache is known as a rare type of primary headache related to sexual activity. The pathogenesis of this type of headache remains unknown. Clinical manifestation is typical and connected with three phases of sexual activity. Coital cephalalgia is divided into two subtypes: preorgasmic and orgasmic headache. Some authors specifie the third type--postural type. Preorgasmic headache starts as a dull bilateral ache and increases with sexual excitement. Orgasmic headache has sudden, intense character and occurs at orgasm. Postural headache has been reported to develop after coitus. The author describes four cases of different types of sexual headache, which were effectively treated. Indomethacin was effective in all patients as direct treatment and propranolol was effective in patients to whom it was administrated as preventive treatment.

PMID:16566381[PubMed
===================
2.J Neurol Sci. 2008 Oct 15;273(1-2):142-3. Epub 2008 Jul 26.
Recurrent emotion-triggered headache following primary headache associated with sexual activity.
Kim HJ, Seo SY.
SourceDepartment of Neurology, Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do, Republic of Korea. movement@ilsanpaik.ac.kr

Abstract
We present a 44-year-old woman who was admitted to our hospital after three episodes of coital headache. Magnetic resonance imaging (MRI) and angiography (MRA) revealed no vascular abnormality. She was discharged with a diagnosis of primary headache associated with sexual activity (PHSA). Although she abstained from sexual activity after discharge, she experienced recurrent headaches several times a day, whenever there was a change in her emotional state. This case implies that emotional changes can trigger headache attacks during headache-prone state in PHSA.

PMID:18656903[PubMed -

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Potter on Nov 23rd, 2012 at 1:44pm
Try unscrewing your cover.

           Potter

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 23rd, 2012 at 1:51pm

Potter wrote on Nov 23rd, 2012 at 1:44pm:
Try unscrewing your cover.

           Potter


I don't understand why you're being so hostile, potter.  There's simply no other purpose for this thread other than to help others. 

Gravity existed long before Newton discovered it

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 23rd, 2012 at 1:52pm
And not one of the links I posted has some secret underlying buy this book or buy this program incentive, they're  simply forums and articles that Ive linked to.

there's absolutely no money involved if that's where you're going

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 23rd, 2012 at 2:03pm
Anyway

UPDATE:  Since last night little "experiment" I've had 2 CH shadows.  One that I posted about last night, and one this morning.  I think I may have had 2 this morning, as I remember injecting myself several times and refilling my cartridges twice...

Started to get another shadow about an hour ago, so in order to abort it without reaching my Imitrex-24 hour limit, I took a hot shower.  It aborted it for the duration of the shower and came back as soon as I got out.  SO I went to DD and got an XLarge Dunkaccino with a turbo shot of espresso.  Last time I checked this was roughly 200mg of caffeine plus whatever is in the turbo shot.  It's workin pretty well.

Definitely will attribute this influx of attacks to the "test" I ran last night.  Dopamine is released during the "search" for porn and satiating the need of watching the video whereas it is theorized that opiates are what are released during orgasm.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Potter on Nov 23rd, 2012 at 2:03pm

Potter wrote on Nov 23rd, 2012 at 1:44pm:
Try unscrewing your cover.

           Potter

A Marine would have understood this.

         Potter

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 23rd, 2012 at 2:12pm

Potter wrote on Nov 23rd, 2012 at 2:03pm:

Potter wrote on Nov 23rd, 2012 at 1:44pm:
Try unscrewing your cover.

           Potter

A Marine would have understood this.

         Potter


I understood it, that's why I asked why you were being hostile.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Potter on Nov 23rd, 2012 at 2:22pm

elliott wrote on Nov 23rd, 2012 at 2:12pm:

Potter wrote on Nov 23rd, 2012 at 2:03pm:

Potter wrote on Nov 23rd, 2012 at 1:44pm:
Try unscrewing your cover.

           Potter

A Marine would have understood this.

         Potter


I understood it, that's why I asked why you were being hostile.

That certainly wouldn't seem like a hostile remark to a Marine.  In fact it would get a chuckle.

            Potter

                

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 23rd, 2012 at 2:39pm
Well I apologize, inflection is lost on the Internet

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Potter on Nov 23rd, 2012 at 2:44pm

elliott wrote on Nov 23rd, 2012 at 2:12pm:

Potter wrote on Nov 23rd, 2012 at 2:03pm:

Potter wrote on Nov 23rd, 2012 at 1:44pm:
Try unscrewing your cover.

           Potter

A Marine would have understood this.

         Potter


I understood it, that's why I asked why you were being hostile.


Maybe you could explain it for the non-Marines.(civilians)

               Potter

   

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Brew on Nov 23rd, 2012 at 3:44pm
If you keep injecting yourself with imitrex, you have anything but a controlled experiment going on, Mr. PhD of Googling Shit.

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Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 23rd, 2012 at 3:57pm
[quote author=1E2E392B5C0 link=1353467596/40#40 date=1353703448]If you keep injecting yourself with imitrex, you have anything but a controlled experiment going on, Mr. PhD of Googling Shit.

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I don't understand.  The frequency is going down(or was, rather, before viewing porn last night); I'm not going to forsake my only means of relief...

And Potter, a cover is what goes on your grape.  Are you jerkin my chain here?  I really could care less if you're being facetious, and if you're not, I apologize.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 23rd, 2012 at 4:06pm
Also, we're talking about Imitrex.  Abortives have no effect on preventing CH, that's what....preventatives are for.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Brew on Nov 23rd, 2012 at 4:07pm
A scientist would understand.

I'm getting a pretty good idea of who's jerking chains around here.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 23rd, 2012 at 4:15pm
Feel free to stop posting then?  Idk what to tell you.


Zeitgeist-
Lol

Lance-
That's interesting, Ill have to do a search for that topic.  I'm in the same boat as you though, the idea of doin the deed during an attack is ridiculous to me.  The last thing I would think to do is go look at porn.




Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 23rd, 2012 at 4:23pm
You all might find this interesting:

During my current cycle, I started a type of meditation I guess you could call it?  At the peak of the pain, I would close my eyes and try to envision exactly where was coming from inside of my skull.  The visual that I got in my brain was electricity shooting in between two cells.  What helped me to ease the pain, although slightly, Was to imagine the surface that the electricity landed on, and essentially instruct my brain to NOT complete the circuit.  I would envision the electricity hitting "dead flesh".  And this seemed to help.

Through my research, I came upon a diagram of dopamine being released and being transferred dopamine receptors.  The process in the diagram is exactly what I envisioned in my brain.  Again, Sounds crazy, but I'm trying to put all the pieces together.  I'll link the diagram/video in the next post.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 23rd, 2012 at 4:27pm
@ 9:30
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Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Zeitgeist on Nov 23rd, 2012 at 4:34pm
Elliot

Assuming it's possible to get any empirical evidence for the hypothesis - have you  done any work on that? 

(For instance CH should be less occuring among assumed non-masturbating porn viewing maniacs like monks, priests, and other religious)

Granted, these people may be the most heavy meatbeaters of all, but it may be worth a try.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Potter on Nov 23rd, 2012 at 5:25pm

Potter wrote on Nov 23rd, 2012 at 2:44pm:

elliott wrote on Nov 23rd, 2012 at 2:12pm:

Potter wrote on Nov 23rd, 2012 at 2:03pm:

Potter wrote on Nov 23rd, 2012 at 1:44pm:
Try unscrewing your cover.

           Potter

A Marine would have understood this.

         Potter


I understood it, that's why I asked why you were being hostile.


Maybe you could explain it for the non-Marines.(civilians)

               Potter

   


Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Brew on Nov 23rd, 2012 at 6:52pm

elliott wrote on Nov 23rd, 2012 at 4:15pm:
Feel free to stop posting then? 

Yeah, don't worry - that ain't gonna happen.

You understand that so far you have an experiment group of one with a control group of zero, right? Yet you are sure you have cracked the code of what causes CH.

You'll pardon me if I call BS. This isn't just bad science, it's beyond the black stump science.

Get back to me once you've got some solid numbers. And for God's sake stop your ridiculous claims. New members are particularly vulnerable to BS claims like yours.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 23rd, 2012 at 6:58pm
Zeitgeist-
Lol No, I haven't.  I was hoping to get that by responses from non-masturbators in this thread.

Potter-
Wtf do you want from me brother?  A cover is a hat, you're saying my hat's too tight.  Hilarious.  I'm a combat vet.  Infantry. It has nothing to do with this topic. 

Brew-
Yes, I'm a total newbie, but I also share the same condition as everyone else on this website.  I may be drawing conclusions, but at least I'm putting something on the board.  What is getting you off by trolling this thread?

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Brew on Nov 23rd, 2012 at 7:40pm
I'm just trying to stand up for people who might be vulnerable to your crap. Which is more than I can say for you, because you'd stop it if you could actually see how self-involved this is.

I'm done with you. I think my warnings to new members here have been made, and now it's time to take out the trash.

I'm beginning to think that you might be getting your jollies by baiting people into talking about this subject matter.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 23rd, 2012 at 7:47pm
Yeah, because I'd take the time out of my day to do all of this to "get my jollies".  I've been diagnosed with clusters for 3 years.  I'm putting all of the pieces together on everything I've learned since then.

Your profile says you're 51, act like it.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 23rd, 2012 at 7:50pm
And if you leaving this topic for good is "taking out the trash", well then...lol, I'd have to agree.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Brew on Nov 23rd, 2012 at 7:53pm
You crack me up.

Not.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Zeitgeist on Nov 23rd, 2012 at 7:55pm
Brew - what is the problem?  Some Believing "newbies" having to suffer some attacks before they give it up and explore other means of pain control?

It will soon enough show if Elliot's theory has any merits.  Bashing it prematurely is just bad, then we won't even know if it has no merits.

The D3 regimen was met with exactly the same attitude. Bashing besserwissers in great numbers lining up in front of the ever-working Jukebox of Eternal Bitterness.

Let this play itself out. Effective or not, it will soon enough reveal itself. Dopamine and CH may be related.  Elliot's methods may be crude, but so what?



Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 23rd, 2012 at 7:56pm
And I do hope you understand the difference between a hypothesis and a thesis.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 23rd, 2012 at 7:58pm
Thanks zeitgeist...

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by MDR on Nov 23rd, 2012 at 8:11pm
Elliott, you need to go else were find your kicks on some other board 

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Zeitgeist on Nov 23rd, 2012 at 8:13pm
I copy parts of the answer to a PM I received.

We can bash and trash every new idea and refer to o2, D3, and all the other tried and proven but not 100% effective stuff for the next 50 years.  The answer to what CH is all about or an all over effective medicine will most likely have to be discoverd by us.  Hammering down every new idea is not helping.

Adding:  We need ideas, and wee need an environment where ideas can flourish. Basically we need the principles of Brainstorming.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 23rd, 2012 at 8:18pm

MDR wrote on Nov 23rd, 2012 at 8:11pm:
Elliott, you need to go else were find your kicks on some other board 


What pleasure would I gain from this?  None.  I'm abstaining from porn and posting the results based on links between dopamine and the trigeminal nerve.  Please stop flooding my thread.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 23rd, 2012 at 8:22pm
ZG, not implying that you're taking sides, but I really appreciate you speaking up.  Thanks

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Zeitgeist on Nov 23rd, 2012 at 8:46pm
elliot - No, I'm not taking sides.  But I cannot dismiss the dopamine idea. Restraining myself from sex or masturbation is not a realistic prospect for this sucker, but if someone will in order to produce results related to you hypotehsis, I praise them.

But be aware - From time to time people show up on this board with "the final solution" to CH, and quite a few are well, pissed and also concerned that sufferers in their desperation will waste valuable life and suffer great pain all in vain. I respect that, and so should you.

(Edit, expanding:)
A number of people on this board have a lifetime of CH experience. I myself have 21. You have 3. Most of us are painfully aware that the causality behind CH is complex, not simple. It is almost common that people show up on the board with a message of restrain from this or restrain from that, do this, do that, do less of this or more of that and your CH will be gone.

If you search, you will find people advocating masturbation as the best abortive ever. Please consider this, and store it somewhere in the back of your mind. If nothing, it will help you understand the opposition you've faced. Basically, we're a collective, having accumulated hundreds. maybe thousands of years of severe pain saying Don't f. with us. Again, please consider this. Some of us smell snake oil miles away.
(done expanding)




Over to the science here.  I'm not able to tell if dopamine and CH is not related.  In fact I got a hunch you're on to something.  But the theory will have to explain quite a number of phenomena related to CH - like:

  • Why can one masturbate multiple times a day, all the year, and still suffer from CH only in periods?
  • Why can I have sex at all?
  • Why are some people episodics and others chronics?
  • Why does Imitrex and O2 abort?
  • Why do a number of stuff prevent?


(expanding)
My general belief is that we must accept, allow and even encourage bad ideas in order to get the good ones. This requires a certain environment.  Bad ideas may inspire the better ones, and very often they do. Good ideas are born from a graveyard of bad ideas, as I see it.

This is why I welcome ideas, even strange and apparently stupid ones. Obviously the complete understanding of CH requires knowledge not yet revealed. It may even require a paradigmatic shift in the science of brain chemistry, or electricity to explain CH. This is why I'm open, and not instinctively dismissive.  Sometimes the truth is not the obvious. All practicality says that if I throw a ball, I apply an amount of power that drives the ball ahead, and when that power is consumed, the ball will hit the ground. Like an airplane with a limited amount of fuel. Enjoying very special minds like Newton, we know that this is not how it works. For all I know, the understanding of CH may require a similar ground-breaking thought, an idea that seems incredibly stupid - at first.

Having said that - there is logic, the best tool ever created. And there is this board which is the best source of information about CH in the known universe.
Just to make sure it is mentioned.
(done expanding)

Having an opposed idea is hard. But I wish you good luck!

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 24th, 2012 at 9:51pm
I'm not here to piss anyone off.  I just deleted everything I wrote after that sentence, because I figured that covered the point of it all...  But again, thank you for coming to my defense.

UPDATE:  No CH today.  Very very small shadow when I woke up, took a hot shower and shrugged it off.  No caffeine, no imitrex.  IF my cycle just ended "normally", it will have been the shortest cycle I've ever had.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 24th, 2012 at 10:06pm

Quote:
Why can one masturbate multiple times a day, all the year, and still suffer from CH only in periods?
Why can I have sex at all?
Why are some people episodics and others chronics?
Why does Imitrex and O2 abort?
Why do a number of stuff prevent?


1.  I believe it still has to do with the circadian rythm.  Forcing changes upon it through daylight changes.  I believe that the endocrine system undergoes an adaptation phase that has trouble "doing work" with damaged dopamine receptors. 
2.  Sex is linear.  Assuming its not with multiple partners, the dopamine release will be conditioned and adapted to within the boundaries of nature.  Even several partners.  Pornography affords hundreds of partners at our disposal, ousting our primative ancestors in one session an experience they could not achieve in a lifetime.
3.  Two possible scenarios: genetically "flawed" brain mapping.  This could be be biggest variable in CH in general.  Some people are born with webbed toes, some with malfunctioning receptors.  Second scenario:  misdiagnosis of severe, non-cluster headaches. 
4.  Enhancing oxygen and blood flow to the brain promote healthy nerve transmissions.  Not quite sure how imitrex works though.
5.  I have never been put on an effective preventative, but I assume they also promote blood flow to the brain.  Really don't have an answer for this one.

All that being said, those are my best GUESSES.  I'm really optimistic about how this trial is going though, cluster free today and hopefully forever.

Cheers

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Batch on Nov 24th, 2012 at 10:23pm
Or...  you could be suffering needlessly from cluster headaches due to an easily remedied vitamin D3 deficiency...

Better than 76% of the 250 CH'ers, who have tried the anti-inflammatory regimen with 10,000 IU/day or more vitamin D3, have reported this to be the case...

Get the lab test for 25(OH)D next week and prove me wrong...

Take care,

V/R, Batch

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 25th, 2012 at 2:05pm

Batch wrote on Nov 24th, 2012 at 10:23pm:
Or...  you could be suffering needlessly from cluster headaches due to an easily remedied vitamin D3 deficiency...

Better than 76% of the 250 CH'ers, who have tried the anti-inflammatory regimen with 10,000 IU/day or more vitamin D3, have reported this to be the case...

Get the lab test for 25(OH)D next week and prove me wrong...

Take care,

V/R, Batch


Batch-  not trying to downplay this, but 3/4 of teens and adults in the United States are vitamin D deficient.  I drink my milk and as a Marine get my fair share of time in the sun.  I WILL do my best to get this test done, but just know that I really feel that vitamin d could only play a part in this.  Vitamin D plays a role in producing dopamine after all...

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Brew on Nov 25th, 2012 at 5:08pm
Batch - Don't argue. We have an expert amongst us.

It's okay, though. More D3 for you and me.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 25th, 2012 at 7:09pm

Brew wrote on Nov 25th, 2012 at 5:08pm:
Batch - Don't argue. We have an expert amongst us.

It's okay, though. More D3 for you and me.


Could've sworn you said you were done with this harassment.  You're 51 years old.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by MDR on Nov 25th, 2012 at 7:59pm
I Google masturbation and cluster headaches and there was a discussion on this back in 2006 on this message board  go look it up it was beat to death. PF to you Mark Roberts

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 25th, 2012 at 9:17pm

MDR wrote on Nov 25th, 2012 at 7:59pm:
I Google masturbation and cluster headaches and there was a discussion on this back in 2006 on this message board  go look it up it was beat to death. PF to you Mark Roberts



Not so much masturbation MDR, as the chemical there is an opioid.  What stimulates the dopamine cycle is the "hunt" for material.  Dopamine is what gets people to move from playboys to hustlers.  Softcore to hardcore

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by MDR on Nov 25th, 2012 at 9:39pm
Just Google and read that all I'm saying

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by AussieBrian on Nov 25th, 2012 at 9:41pm
What about us CHeads who go nowhere near porn, ever, and keep our hands out of our own trousers?

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Brew on Nov 25th, 2012 at 10:14pm

AussieBrian wrote on Nov 25th, 2012 at 9:41pm:
What about us CHeads who go nowhere near porn, ever, and keep our hands out of our own trousers?

Or the ones that fantasize during sex?

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 25th, 2012 at 10:50pm

AussieBrian wrote on Nov 25th, 2012 at 9:41pm:
What about us CHeads who go nowhere near porn, ever, and keep our hands out of our own trousers?



This is an important variable and feedback from you guys adds to the study.  Are you saying you don't masturbate to porn or at all?


UPDATE:  Another CH-free day.  Had a shadow of a shadow.  Things are looking good. 

I'm losing my mind doing this though.  For Science!

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by AussieBrian on Nov 26th, 2012 at 12:30am

elliott wrote on Nov 25th, 2012 at 10:50pm:
Are you saying you don't masturbate to porn or at all?

I'm saying both, and think I'd rather remain a CHead than indulge in either practice.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Potter on Nov 26th, 2012 at 9:19am

elliott wrote on Nov 15th, 2012 at 10:55am:
My cluster period started a few weeks ago.  Just shadows at first, for about a week, and then a big one.  And then another.  I steadily went from one a day to four a day.  I peaked at this amount, injecting myself with 24mg of Imitrex throughout the day.

During my 4th or 5th round at the ER (my physician is always out of pocket) they injected me with nerve blockers.  This is the only variable I can think of that could interfere with my conclusion in this topic.  But on to the real subject:

What provides me with relief?  I've heard plenty of people say caffeine does the trick.  I've tried regular coffee, caffeine pills and en the biggest Redbull they sell with absolutely no results.  Please don't laugh, scoff or (if you're in the middle of a cluster cycle) hate me for seemingly misleading you, I assure you that's not my intention. 

I have found relief in Dunkin Donuts Extra Large Dunkaccino. 
This thing is a whopping $2.50.  It's on the menu, and no I did not mean cappuccino.  It's like hot chocolate with espresso or something, but I swear as soon as I tried this freakin thing my headaches went away.  I woke up at 2 AM the night after or the next night and the cycle continued right where it left off.  Then 2 days after I got another one because I thought it was so good, and bam it ended it again.  I'm willing to ride this entire cycle out regardless of the 1000 or so calories that's in this thing. 

Like I said, caffeine has never worked for me before.  I'm pretty sure Redbulls have their fair share.  Someone test this and confirm my findings please, and I hope to God I'm not an idiot and you find relief.

  Never heard of out of pocket for health care for our military.

                       Potter

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 26th, 2012 at 11:21am
Potter.  Get.  Off.  My.  Fucking.  Back.

You don't know how the Marine Corps works.  You don't just walk into BAS and talk to your medical officer.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 26th, 2012 at 11:23am

AussieBrian wrote on Nov 26th, 2012 at 12:30am:

elliott wrote on Nov 25th, 2012 at 10:50pm:
Are you saying you don't masturbate to porn or at all?

I'm saying both, and think I'd rather remain a CHead than indulge in either practice.


Then you are presenting the variable that seemingly nulls my hypothesis, which is what I was afraid of.  Are you episodic or chronic?

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Potter on Nov 26th, 2012 at 11:30am

elliott wrote on Nov 26th, 2012 at 11:21am:
Potter.  Get.  Off.  My.  Fucking.  Back.

You don't know how the Marine Corps works.  You don't just walk into BAS and talk to your medical officer.

I understand how it works just fine. Maybe just maybe yer bullshit is unravelling.

         Potter

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 26th, 2012 at 2:21pm
Potter, it's as simple as not posting in my thread.  You boot.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Brew on Nov 26th, 2012 at 2:44pm
It's been a week now. I wonder how many volunteers there are for this "study."

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Potter on Nov 26th, 2012 at 2:54pm

elliott wrote on Nov 26th, 2012 at 2:21pm:
Potter, it's as simple as not posting in my thread.  You boot.


  I was walkin point in Vietnam before your folks was born.

         Potter

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 26th, 2012 at 3:04pm
If my dad were still alive he would be 71.  As a fellow pointman, why the hell are you constantly bashing me.

Just don't click this topic, it's that simple.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Brew on Nov 26th, 2012 at 3:10pm
Because we all know that threads are owned by people.

Seems some thread "owners" become a little sensitive when their ideas come into question and start getting called out for the nonsense they are.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 26th, 2012 at 3:18pm
But that's not what's going on here, the content of my thread isn't being called into question, I am.  As if I have some ulterior motive behind this.  What in the fuck do I have to gain from presenting this idea and conducting this experiment?  You are finding joy in harassing the fuck out of me.  Don't you have children that need your attention?

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 26th, 2012 at 3:19pm
In fact, Brew, since you can't leave it alone, I'm going to utilize this little ignore button under your username.  Should've done this from the start.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Brew on Nov 26th, 2012 at 3:42pm
Since the point earlier in this thread where I stated I was done with you, I have not addressed you directly. But since you seem to have a need to pick the scab, I challenge you to point out one instance in this thread where I criticized you personally and not your ideas.

From the clusterheadaches.com Standard of Conduct:

Quote:
Debate is welcome (and encouraged), but attack ideas and opinions; not personalities.


Methinks you need to reevaluate how you separate your personality from your thoughts and ideas.

And please tone down the language - kids read this stuff.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by coach_bill on Nov 26th, 2012 at 7:48pm
Fu@@@k  it. I'm gonna set my self up here.

That jerking off theory is wanked!!  I'm sure their is at least one guy in here that don't masturbate?? Right? Someone (male) stand up and tell this guy he is wrong. Someone??? Anyone???

Anyway, I believe it is a bad link in the DNA chain. As we evolved as a species, that Gene has modified its self, kind of a splice off the old migraine gene. I think it goes way way way back, to the days of migration.

Yes, that's right.. get over yourself, It wasn't just a couple thousand years ago we were still dragging our knuckles. And i think when the days grew shorter back then, we would start our migration.

I believe the gene developed as a response to migration, When we as a species stopped or failed to migrate... The brain would send out any warning that it could, and what gets the body up and moving faster than pain does?? thus the DNA evolved as a way to reset our brain clocks, And start or stop the migration process.  And so on, and so on, and so on.

So before you blast me, remember it was only about 100 years ago that we were able to pack and preserve food to share with the world, and even less time than that, we had aspirin.

Coach Bill

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Linda_Howell on Nov 26th, 2012 at 9:40pm

Quote:
but I'm a friggin high school student who's been in the military for 4 years.  Sorry


How is that possible?   just asking.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by AussieBrian on Nov 27th, 2012 at 5:54am

elliott wrote on Nov 26th, 2012 at 11:23am:

AussieBrian wrote on Nov 26th, 2012 at 12:30am:

elliott wrote on Nov 25th, 2012 at 10:50pm:
Are you saying you don't masturbate to porn or at all?

I'm saying both, and think I'd rather remain a CHead than indulge in either practice.


Then you are presenting the variable that seemingly nulls my hypothesis, which is what I was afraid of...

Don't give up too soon, mate. There's some wankers make your theory look perfectly plausible.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 27th, 2012 at 11:31am
Bill-
Going to ignore your theory for a moment and backtrack to the first part of your post:
Are you saying you're not one of those people?  If you are just give it a shot and stop giving it a wank.  My first CH free day was 5 days in.  It's not that ridiculous of a request to go a week without it...

EDIT:  More important than actually masturbating, is to NOT LOOK AT PORN for those 5 days, as viewing it is what delivers the dopamine rush.

Linda-
What I'm saying is I went straight from high school (18) to the military (22, now).  I'm still high school educated is what I mean.

Aussie-
Thanks for the vote of confidence mate, might be disappointed with my update though...

UPDATE:  Couldn't take it anymore.  Had to crank one out yesterday at about 10 days in (too many suggestive text messages from my girl).  Guess what came back?  Strong shadows.  First last night, that one wasn't too bad.   Then had one today while sitting in a classroom, got pretty intense and had to shoot myself with the 'ol Imitrex.

1 step forward and 5 steps back, personally, but it looks like 1 step forward as far as results in this little experiment.

So as of right now, for me, this is how it is going:

5 days after stopping masturbating, drastic reduction in amount of CH.  Over the next 5, no CH at all and drastic reduction in intensity of shadows.  Day 10, "relapsed" and experienced day 5 shadows and day 1-5 cluster kip level the following morning.

Hope that horrendous paragraph is discernible.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 27th, 2012 at 11:39am
Also it should be noted that this was the first time I've had to use the Imitrex injection in about 5 days(too lazy to read my previous posts and find out exactly when).

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by seaworthy on Nov 27th, 2012 at 12:00pm

Quote:
We may not watch as much porn as guys


But you have your bases covered!

Shades of Grey

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Brew on Nov 27th, 2012 at 12:00pm
The experiment of one, with no control group, continues...

That thar's reel gud sy-ince.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Potter on Nov 27th, 2012 at 12:09pm

Linda_Howell wrote on Nov 26th, 2012 at 9:40pm:

Quote:
but I'm a friggin high school student who's been in the military for 4 years.  Sorry


How is that possible?   just asking.

   Key phrase.

         Potter

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 27th, 2012 at 12:37pm
Potter-  I invite you to take a look at your last 40 posts.  Thanks for your contributions to this website.  Your witty contributions.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 27th, 2012 at 12:42pm
And to backtrack: 
When I said "out of pocket" I meant not in his office, not money out of my pocket.  Fuckin a', simple misunderstanding and you rode it like a show pony.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Potter on Nov 27th, 2012 at 12:51pm

elliott wrote on Nov 27th, 2012 at 12:42pm:
And to backtrack: 
When I said "out of pocket" I meant not in his office, not money out of my pocket.  Fuckin a', simple misunderstanding and you rode it like a show pony.


You must be a desk Marine cuz any Rifleman wouldn't have this much time to defend a flawed theory.

            Potter

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by pattik on Nov 27th, 2012 at 2:04pm

seaworthy wrote on Nov 27th, 2012 at 12:00pm:

Quote:
We may not watch as much porn as guys


But you have your bases covered!

Shades of Grey

Okay...no books, no soap operas, no chocolate or shopping.  Will life be worth living? 8-)

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 27th, 2012 at 2:20pm

Potter wrote on Nov 27th, 2012 at 12:51pm:

elliott wrote on Nov 27th, 2012 at 12:42pm:
And to backtrack: 
When I said "out of pocket" I meant not in his office, not money out of my pocket.  Fuckin a', simple misunderstanding and you rode it like a show pony.


You must be a desk Marine cuz any Rifleman wouldn't have this much time to defend a flawed theory.

            Potter


Potter, seriously, grow up.  I have this free time because I'm 4 years in and I no longer have a billet.  I'm waiting to get out.  This is not the time or place to have a pissing contest.  I'm Infantry.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 27th, 2012 at 2:22pm

pattik wrote on Nov 27th, 2012 at 2:04pm:

seaworthy wrote on Nov 27th, 2012 at 12:00pm:

Quote:
We may not watch as much porn as guys


But you have your bases covered!

Shades of Grey

Okay...no books, no soap operas, no chocolate or shopping.  Will life be worth living? 8-)



Lol, Patti are you episodic or chronic?

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Zeitgeist on Nov 27th, 2012 at 2:31pm

Brew wrote on Nov 27th, 2012 at 12:00pm:
The experiment of one, with no control group, continues...


And the history of medical science have numerous examples of this.  Quite a few resulting in major medical breakthroughs, for instance Max von Pettenkofer,  Werner T.O. Forssmann,  John Paul Stapp, Erik Jacobsen, Barry J. Marshall, John H. Crandon.

One might add Walter Reed - the one in Walter Reed Army Hospital i Washington DC. (Though his associates Jesse Lazear (died) Aristides Agramonte (permantly injured), James Carroll (almost died) were the real heroes).

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by pattik on Nov 27th, 2012 at 2:37pm

elliott wrote on Nov 27th, 2012 at 2:22pm:
Lol, Patti are you episodic or chronic?


Quote:
This is where my theory falls short and I chalk it up to either misdiagnosis of severe migraines, or perhaps damaged dopamine receptors from birth.  Sorry ladies but my theory fails you.
Neither, since I apparently only have migraine or a misdiagnosis.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Nov 27th, 2012 at 2:44pm
Zg - I love you.

Patti-  well can you answer anyway so I can think on it

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Brew on Nov 27th, 2012 at 3:15pm

Zeitgeist wrote on Nov 27th, 2012 at 2:31pm:
And the history of medical science have numerous examples of this.  Quite a few resulting in major medical breakthroughs, for instance Max von Pettenkofer,  Werner T.O. Forssmann,  John Paul Stapp, Erik Jacobsen, Barry J. Marshall, John H. Crandon.

One might add Walter Reed - the one in Walter Reed Army Hospital i Washington DC. (Though his associates Jesse Lazear (died) Aristides Agramonte (permantly injured), James Carroll (almost died) were the real heroes).

My point was that there are seemingly no volunteers to help further this cause.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Brew on Nov 27th, 2012 at 3:48pm
I think I'm kinda done with this whole concept and this thread. It was intriguing at first - now it's just tiresome.

You kids play nice now.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Zeitgeist on Nov 27th, 2012 at 4:16pm

Brew wrote on Nov 27th, 2012 at 3:15pm:
My point was that there are seemingly no volunteers to help further this cause.


No one wanting to risk life, no one wanting to stop watching porn or jerking off - what's the difference!

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by LasVegas on Nov 28th, 2012 at 3:25pm
33 years ago when I was 11 years old, after surviving a head trauma, my CH's began.  Of course I was misdiagnosed throughout my entire life until I self-diagnosed myself from the Cluster Quiz on this website back in 1999 and then confirmed by several headache specialists.

Last year when I was in a cycle from Hell, I asked my mother what she recalls about any neurological findings when I was a kid back in the 1980's as it related to my CH's.  She stated there were reports about me that stated I had abnormal dopamine levels.  Unfortunately I no longer have those test results nor reports and do not remember who conducted those testings.

I inquired with my neurologist last year about dopamine testing as it relates to CH's.  He told me it was a very sophisticated test and since I had no health insurance, I never followed through.

However, there is a correlation between dopamine levels and the hypothalamus.  Magnesium deficiency can also cause decreased levels of dopamine.  Whether or not dopamine or magnesium is the cause of CH's is obviously to be determined.  I find it unlikely such a worldwide mass study of Ch'ers will ever result.

My suggestion if a CH'er were to be a "guinea pig" is to have the testing focus on dopamine and also magnesium levels.

Further to note, in my opinion, this thread has definitely gotten way off track with theories of watching porn, masterbation, etc causing CH's.

Just my 2 cents. ;)

-Gregg in Las Vegas

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Zeitgeist on Nov 30th, 2012 at 8:33pm
elliott - Isn't there some more viable way to experiment?

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Dec 1st, 2012 at 11:31am
Las Vegas - that dopamine defiency is very interesting, but I don't understand why you think this topic has gotten out of hand as far as the subject.  Dopamine receptors being damaged from porn use is a huge emerging theory...

Zg-  how do you mean?  I expected others to join with me and post whether or not this worked.  It has definitely ended my cycle.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Ricardo on Dec 3rd, 2012 at 9:09am
There have definitely been people saying that they do not masturbate and still get clusters bad.  On both this site and Clusterbusters.  The biggest question I have is- Why are you pressing on with this while completely ignoring these responses?

I myself have definitely gone much much longer than 5 days without masturbating and had absoloutly no increase or decrease in clusters. 

Clusters come and go.  If you didn't masturbate for a full year and had them go away, this thread might make sense...And I doubt anyone is going to take this seriously until a much much longer "testing period" happens for you.  You can keep arguing with people about why you are right, with absoloutely no evidence to back it up, or you could do your test and report back after a much longer amount of time.  Your first post on this was less than 2 weeks ago.  If you ask long time sufferers if they have amounts of time where things got better for some reason for different amounts of time the answer is almost always yes.  You can find all sorts of people who claim they figured out their cluster cure by mangosteen, jumping jacks, sex, masturbation, the list goes on and on.  Eventually it seems like 90% of those folks come back and say "I guess I was just having a lucky month/week/day."

All questions are worth asking, but I would say unless you have some sort of actual concrete evidence of some sort of long term change happening, it's probably not doing much good to just beat a subject to death.  (no pun intended)

Your idea that what happens in your brain when you watch porn is that dopamine is released is true, but very simplistic and not complete.   A hell of a lot more happens in your brain than just this one hormone being increased.  One big hole in the "too much dopamine" idea is that routinely people have found that cocaine IS effective for many peoples clusters.  Talk about dopamine overload.  LSD boosts dopamine too, and many people have found it to get rid of clusters for months at a time. 

Another thing to do research on--there is actually a condition called "dopamine syndrome"  It has nothing to do with masturbation or cluster headaches.

-Ricardo

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Dec 4th, 2012 at 11:37am

Ricardo wrote on Dec 3rd, 2012 at 9:09am:
There have definitely been people saying that they do not masturbate and still get clusters bad.  On both this site and Clusterbusters.  The biggest question I have is- Why are you pressing on with this while completely ignoring these responses?



Are you kidding me...

1 person.  1 person has stepped up to the mic and told us this.  Out of almost 2000 people.  And I grilled him for questions.  How the Is that ignoring.


Seriously, cluster headaches come and go, my dopamine theory has holes in it (I'm no scientist, Jack) and people find relief through LSD.

So what you're saying is, you have NO IDEA what the cause of clusters are.  Look brother, this worked FOR ME.  I've gone 3 months without masturbating in the past and I didn't notice that I didn't get my season cluster.  6 months after that, my girlfriend at the time broke up.  I started looking at porn a lot more and having CH A LOT more.  I never made the connection before, but based on that past experience is where I came up with this theory.

AND IT WORKED.  Don't stimulate dopamine for 10 days.  I don't care if it's porn, cocaine, gambling, killing people DON'T STIMULATE DOPAMINE. 

I started binging on porn after my "relapse", shadows came back.  There's a correlation here.


EDIT:  this entire topic talks about sex and pornography, and you all lost your minds over 3 F word's?  Are we adults?

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by BobDeb on Dec 4th, 2012 at 11:55am
ELLIOTT...STOP USING THIS LANGUAGE...WOMEN & CHILDREN READ THESE POSTS..HAVE RESPECT FOR OTHERS AT LEAST.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by wildhaus on Dec 4th, 2012 at 1:26pm
You must be joking…………..
(Or not?)
Please  save your breath,
and time….

To the new CH.com residents…..
This website is offering real knowledge, Real experience,
Be it the Anti-Inflammatory Regimen, or Oxygen treatment
Or the busting treatment…….
Which we all know can help to reduce the suffering (distinctively)
I do not suggest ignoring new ideas, but some sort of common sense
Is required…. Some sort of self criticism…..
BTW
My sons are reading this website….  One is 15 the other is 11, it’s the way
they learn how to support me…..
I humbly ask to think before posting…… before abusing the language in
the name of a good deed…..
And back to my obscurely……….
Michael

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by LasVegas on Dec 4th, 2012 at 2:41pm

BobDeb wrote on Dec 4th, 2012 at 11:55am:
ELLIOTT...STOP USING THIS LANGUAGE...WOMEN & CHILDREN READ THESE POSTS..HAVE RESPECT FOR OTHERS AT LEAST.



Agreed!  Moderator Alert! >:(

-Gregg in Las Vegas

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Potter on Dec 4th, 2012 at 2:53pm
Hypothesis:  Since Elliot is a Marine and this Marine has a limited vocabulary and uses foul language to get his point across then all Marines must have limited vocabulary skills and all Marines use foul language.  Does it hold water?

                              Potter
                  

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Melissa on Dec 4th, 2012 at 4:33pm
I'm sorry, but unless Elliott is attacking another member, I cannot censor him due to vulgar language.

CH.com members please read the site Standard of Conduct to see what is not tolerated. START PRINTPAGEMultimedia File Viewing and Clickable Links are available for Registered Members only!!  You need to Login or RegisterEND PRINTPAGE

Thank you and please try to remember to be respectful to others.

-Melissa

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Brew on Dec 4th, 2012 at 4:51pm
Since the moderators cannot stop elliott from using all the vulgar language he chooses to use, I would simply encourage all y'all to stop engaging him.

After you personally thank him for chasing your kids off this site.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by DJ on Dec 4th, 2012 at 10:59pm
I'm not going to decide what words people can and can't use.  If someone wants to use vulgar language... that's on them.  Most people try to be respectful to the rest of the community... some don't care.

If you don't like the way someone is typing, use the "ignore" button.  If you don't want to do that, keep in mind the type of person you are dealing with when you interact with them and don't be surprised when they drop an "F" bomb.

If that type of language is directed towards someone, that is a completely different story.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by jon019 on Dec 5th, 2012 at 12:04am

Brew wrote on Dec 4th, 2012 at 4:51pm:
I would simply encourage all y'all to stop engaging him.



Hmmm...sounds familiar...I'll SECOND that emotion...just give me a minute to remove the blue cheese stuffed up my nose (my Iti Grands taught me that a good creamy Gorgonzola don't cure caca, but is  soothing to the soul...green over blue), the cayenne pepper up the other nostril (THE elemental sinusbuster...doncha know?), the tin foil hat off my head, the vinegar shot off the table, the head band off my head, the finger off my carotid, the arterial ligation delayed, the accupuncture needles out of my back,  the chiro off my spine, go vegan WITH coffee enemas (I prefer it black...cream leaves a ring),  the porn site shut down, AND the hand out of my pants......

If you REALLY want a CURE...lissen to me: Peewee Herman's Playhouse!!! I got hit once...watched a Peewee marathon...and 90 minutes later the hit was GONE! Works EVERY time..just keep Peewee out of theaters and guar-an-dam-teed....

Best,

Jon



Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by elliott on Dec 5th, 2012 at 10:28am
So anyway...

UPDATE:  After my  "relapse" last week, I've gone on a steady diet of doing it every day (binging, is what they call it in the reboot community).  Every day except Sunday.  The shadows have been fleeting, but noticeable, whereas before I started binging they were gone completely. 

Sunday morning, I want to say, someone I contacted on a Cluster Headache Support Page on Facebook responded to my message.  He said it made sense and would be well on his way to undertake the task.  He is episodic and is in the middle of a cycle right now.  Will contact him today and see what's up with that.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Linda_Howell on Dec 5th, 2012 at 11:46am

Jon...I am LMAO and tears are  streaming down my cheeks at your post.  Have I told you lately that I love ya?    [smiley=crackup.gif] [smiley=crackup.gif] [smiley=crackup.gif]

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Potter on Dec 5th, 2012 at 11:51am

jon019 wrote on Dec 5th, 2012 at 12:04am:

Brew wrote on Dec 4th, 2012 at 4:51pm:
I would simply encourage all y'all to stop engaging him.



Hmmm...sounds familiar...I'll SECOND that emotion...just give me a minute to remove the blue cheese stuffed up my nose (my Iti Grands taught me that a good creamy Gorgonzola don't cure caca, but is  soothing to the soul...green over blue), the cayenne pepper up the other nostril (THE elemental sinusbuster...doncha know?), the tin foil hat off my head, the vinegar shot off the table, the head band off my head, the finger off my carotid, the arterial ligation delayed, the accupuncture needles out of my back,  the chiro off my spine, go vegan WITH coffee enemas (I prefer it black...cream leaves a ring),  the porn site shut down, AND the hand out of my pants......

If you REALLY want a CURE...lissen to me: Peewee Herman's Playhouse!!! I got hit once...watched a Peewee marathon...and 90 minutes later the hit was GONE! Works EVERY time..just keep Peewee out of theaters and guar-an-dam-teed....

Best,

Jon

Yer killin me.

          Potter

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by JHK07 on Dec 5th, 2012 at 1:39pm
    One of the worst clusters of clusters I've had was whilst having sexual relations on a daily basis with an Extremely Hot Crazy Psycho Bitch.  Dopamine Overload..........   
    


Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by AussieBrian on Dec 5th, 2012 at 4:50pm
I imagine someone talking to his hand-puppet, "Not tonight, dear. It'll give me a headache."

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Brew on Dec 13th, 2012 at 9:32pm
I wonder if somebody's gone blind and can't find the keyboard.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by CDog on Dec 14th, 2012 at 6:32am
Funny, but you couldn't just let this die?

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Brew on Dec 14th, 2012 at 7:07am
Perhaps not.

Title: Re: LOOKING FOR GUINEA PIGS "Dopamine Syndrome" Trials
Post by Melissa on Dec 14th, 2012 at 7:48am
This thread has outlived its usefulness.

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