Post by Batch on Jan 29th, 2015 at 4:23pm
Hey Jul,
As long as you're not in cycle and not scheduled to be so for at least 3 weeks to a month, there's no need for an accelerated vitamin D3 loading schedule. You've also time to get a lab test for your 25(OH)D, a.k.a., 25-hydroxyvitamin D serum concentration after you've been on this regimen at least a month. All of us should know the concentration of this vitamin D3 metabolite that keeps us CH pain free.
Unfortunately, bureaucrats at your publicly funded National Health System in Canada have ruled that vitamin D testing is no longer a benefit of the Medical Services Plan for patients over the age of 18, unless ordered by a specialist. Accordingly you'll likely need to find a local diagnostic lab and pay for this test out of pocket. These tests cost between $50 and $65 here in the US.
The rationale for taking a vitamin D3 loading dose is simple. As you correctly pointed out, it's the fastest way of elevating serum 25(OH)D from deficient, i.e., less than 30 ng/mL, (75 nmol/L) up to the desired serum concentration... In our case as CH'ers, the target 25(OH)D serum concentration is 80 ng/mL, (200 nmol/L). The following chart illustrates the time savings made possible by vitamin D3 loading.
START PRINTPAGEMultimedia File Viewing and Clickable Links are available for Registered Members only!! You need to
or 
END PRINTPAGE
Regarding 10,000 IU/day vitamin D3 as the suggested maintenance dose, see the following chart.
START PRINTPAGEMultimedia File Viewing and Clickable Links are available for Registered Members only!! You need to or END PRINTPAGE
The 25(OH)D response curves per the doses illustrated in this chart were developed by Dr. Robert Heaney, M.D., a professor of endocrinology at Creighton University School of Medicine. He compiled data from several vitamin D3 studies with hundreds people taking vitamin D3 at these doses while being tested for 25(OH)D to come up with these response curves.
I've added the color bands to represent data collected from the online survey of CH'ers taking the anti-inflammatory regimen to prevent their CH as well as lab tests for 25(OH)D reported in posts here at CH.com.
From what I've observed, Dr. Heaney's 25(OH)D response curves are quite accurate. The average 25(OH)D response to a dose of 10,000 IU/day, reported to date by CH'ers experiencing a pain free response, is 78.5 ng/mL, (196.3 nmol/L).
You'll also note that a dose of 5,000 IU/day vitamin D3 results in a 25(OH)D serum concentration response of 60 ng/mL, (150 nmol/L). This 25(OH)D serum concentration appears to be the tipping point at which half the CH'ers are pain free and the other half are still getting hit.
Regarding the the strength of vitamin D3 capsules available in Canada without a prescription... The government bureaucrats in your healthcare system have done it again... You're not alone... We've the same kind of idiot bureaucrats and politicians here in the US who would also like to limit the size of over the counter vitamin D3 to 1,000 IU.
Fortunately you can order 360 of the 10,000 IU vitamin D3 liquid gelcaps over the Internet at the following link from iHerb.com for $20 USD or 5.5 cents a day. I just checked Costco Canada and 10,000 IU worth of the 1,000 IU tablets costs 20 cents a day...
START PRINTPAGEMultimedia File Viewing and Clickable Links are available for Registered Members only!! You need to or END PRINTPAGE
There's no shipping charge on orders over $40 so if you order a years worth of LEF Super K with advanced K2 Complex 4 X $22.50 less a 10% discount or $81 USD:
START PRINTPAGEMultimedia File Viewing and Clickable Links are available for Registered Members only!! You need to or END PRINTPAGE
With a 5% discount for orders over $40, a 10% discount for the first iHerb order, and a quantity discount for the super K, the bill including the international charge comes to $102.35 or 28.4 cents a day for a year's supply of vitamin D3 @ 10,000 IU/day and the Super K.(USD).
I just sent the exact same order above to a friend in Kelowna, BC, Canada. She's recovering from breast cancer surgery. Based on the advise of her Integrative physician and Carol Baggerly, the President of Grassroots Health and a breast cancer survivor, she decided not to go through chemo and radiation therapy... (There's no real evidence that chemo and radiation therapy actually improve the 5 year survival rate).
Instead, she's cut out sugar, refined starches, processed foods and switched to a whole food anti-inflammatory diet. She's also taking the anti-inflammatory regimen... just like we're taking to prevent our CH...
The bill from iHerb came to $102.35 (USD).
I made the mistake of FedExing a similar order to her last year at this time. The FedEx bill for second business day delivery was over $100 for a 2 lb package and I had three pages of US and Canadian customs forms to fill out.
Take care and please keep us posted.
V/R, Batch
As long as you're not in cycle and not scheduled to be so for at least 3 weeks to a month, there's no need for an accelerated vitamin D3 loading schedule. You've also time to get a lab test for your 25(OH)D, a.k.a., 25-hydroxyvitamin D serum concentration after you've been on this regimen at least a month. All of us should know the concentration of this vitamin D3 metabolite that keeps us CH pain free.
Unfortunately, bureaucrats at your publicly funded National Health System in Canada have ruled that vitamin D testing is no longer a benefit of the Medical Services Plan for patients over the age of 18, unless ordered by a specialist. Accordingly you'll likely need to find a local diagnostic lab and pay for this test out of pocket. These tests cost between $50 and $65 here in the US.
The rationale for taking a vitamin D3 loading dose is simple. As you correctly pointed out, it's the fastest way of elevating serum 25(OH)D from deficient, i.e., less than 30 ng/mL, (75 nmol/L) up to the desired serum concentration... In our case as CH'ers, the target 25(OH)D serum concentration is 80 ng/mL, (200 nmol/L). The following chart illustrates the time savings made possible by vitamin D3 loading.
START PRINTPAGEMultimedia File Viewing and Clickable Links are available for Registered Members only!! You need to
or END PRINTPAGERegarding 10,000 IU/day vitamin D3 as the suggested maintenance dose, see the following chart.
START PRINTPAGEMultimedia File Viewing and Clickable Links are available for Registered Members only!! You need to
or END PRINTPAGEThe 25(OH)D response curves per the doses illustrated in this chart were developed by Dr. Robert Heaney, M.D., a professor of endocrinology at Creighton University School of Medicine. He compiled data from several vitamin D3 studies with hundreds people taking vitamin D3 at these doses while being tested for 25(OH)D to come up with these response curves.
I've added the color bands to represent data collected from the online survey of CH'ers taking the anti-inflammatory regimen to prevent their CH as well as lab tests for 25(OH)D reported in posts here at CH.com.
From what I've observed, Dr. Heaney's 25(OH)D response curves are quite accurate. The average 25(OH)D response to a dose of 10,000 IU/day, reported to date by CH'ers experiencing a pain free response, is 78.5 ng/mL, (196.3 nmol/L).
You'll also note that a dose of 5,000 IU/day vitamin D3 results in a 25(OH)D serum concentration response of 60 ng/mL, (150 nmol/L). This 25(OH)D serum concentration appears to be the tipping point at which half the CH'ers are pain free and the other half are still getting hit.
Regarding the the strength of vitamin D3 capsules available in Canada without a prescription... The government bureaucrats in your healthcare system have done it again... You're not alone... We've the same kind of idiot bureaucrats and politicians here in the US who would also like to limit the size of over the counter vitamin D3 to 1,000 IU.
Fortunately you can order 360 of the 10,000 IU vitamin D3 liquid gelcaps over the Internet at the following link from iHerb.com for $20 USD or 5.5 cents a day. I just checked Costco Canada and 10,000 IU worth of the 1,000 IU tablets costs 20 cents a day...
START PRINTPAGEMultimedia File Viewing and Clickable Links are available for Registered Members only!! You need to
or END PRINTPAGEThere's no shipping charge on orders over $40 so if you order a years worth of LEF Super K with advanced K2 Complex 4 X $22.50 less a 10% discount or $81 USD:
START PRINTPAGEMultimedia File Viewing and Clickable Links are available for Registered Members only!! You need to
or END PRINTPAGEWith a 5% discount for orders over $40, a 10% discount for the first iHerb order, and a quantity discount for the super K, the bill including the international charge comes to $102.35 or 28.4 cents a day for a year's supply of vitamin D3 @ 10,000 IU/day and the Super K.(USD).
I just sent the exact same order above to a friend in Kelowna, BC, Canada. She's recovering from breast cancer surgery. Based on the advise of her Integrative physician and Carol Baggerly, the President of Grassroots Health and a breast cancer survivor, she decided not to go through chemo and radiation therapy... (There's no real evidence that chemo and radiation therapy actually improve the 5 year survival rate).
Instead, she's cut out sugar, refined starches, processed foods and switched to a whole food anti-inflammatory diet. She's also taking the anti-inflammatory regimen... just like we're taking to prevent our CH...
The bill from iHerb came to $102.35 (USD).
I made the mistake of FedExing a similar order to her last year at this time. The FedEx bill for second business day delivery was over $100 for a 2 lb package and I had three pages of US and Canadian customs forms to fill out.
Take care and please keep us posted.
V/R, Batch