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http://www.clusterheadaches.com/cgi-bin/yabb2/YaBB.pl Cluster Headache Help and Support >> Medications, Treatments, Therapies >> Common CH "triggers" ? (i.e. drugs not foods) http://www.clusterheadaches.com/cgi-bin/yabb2/YaBB.pl?num=1212629838 Message started by Mikeyy on Jun 4^th, 2008 at 9:37pm

Title: Common CH "triggers" ? (i.e. drugs not foods)
Post by Mikeyy on Jun 4^th, 2008 at 9:37pm

Other than alcohol, are there any other drugs (perscription or other) that seem trigger or exascerbate CHs?

Title: Re: Common CH "triggers" ? (i.e. drugs not foods)
Post by Brew on Jun 4^th, 2008 at 9:56pm

Nitroglycerin.

Title: Re: Common CH "triggers" ? (i.e. drugs not foods)
Post by Guiseppi on Jun 4^th, 2008 at 11:31pm

They will actually use nitro to trigger an attack for CH studies! Definitely one to avoid. Marijuana seems to be a wobbler, a trigger for some but not for others.

Guiseppi

Title: Re: Common CH "triggers" ? (i.e. drugs not foods)
Post by George_J on Jun 5^th, 2008 at 1:27am

There's been some talk that Viagra might be a trigger as well. Here's a reference to an article on the subject:

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Best,

George

Title: Re: Common CH "triggers" ? (i.e. drugs not foods)
Post by LeeS on Jun 5^th, 2008 at 5:12am

Histamine (intravenously or subcutaneously) also induces an attack when sufferers are in bout.

Other agents which may trigger attacks include sildenafil (through PDE5 inhibition), calcitonin-gene-related-peptide (through CGRP receptors), m-chlorophenylpiperazine (a 5-HT1a/2 agonist), fenfluramine (by decreasing brain serotonin) and reserpine (monamine release in general and serotonin).

YMMV of course.

-Lee