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Cluster Headache Help and Support >> Cluster Headache Specific >> Cialis (Tadalafil) for ED - CH interaction

Message started by jish on Feb 10th, 2019 at 5:46pm

Title: Cialis (Tadalafil) for ED - CH interaction
Post by jish on Feb 10th, 2019 at 5:46pm
Hello all, was just wondering if anyone had any experience of taking low dose Cialis (Tadalafil) for Erectile Disfunction when out of a cycle and whether it could cause one?

I read an article saying that doctors are advised to prescribe Tadalafil (Cialis) instead of Viagra in the treatment of ED in CH sufferers.

I know it's a Vasodialtor but i have no real problems with alcohol use when out of a cycle so could a low dose of this drug be any different every once in a while when needed?

Title: Re: Cialis (Tadalafil) for ED - CH interaction
Post by Mike NZ on Feb 10th, 2019 at 9:29pm
Pubmed found only one hit for Tadalafil and CH - START PRINTPAGEMultimedia File Viewing and Clickable Links are available for Registered Members only!!  You need to Login or RegisterEND PRINTPAGE

Can Urol Assoc J. 2014 May;8(5-6):E378-80. doi: 10.5489/cuaj.1736.
Sildenafil can induce the onset of a cluster headache bout.
Lin GY1, Lee JT1, Peng GS1, Yang FC1.

About 25% of patients who are prescribed sildenafil, the phosphodiesterase type 5 (PDE-5) inhibitor, for erectile dysfunction (ED) experience headaches. These migraine effects are well-described, including cluster headaches. We report the case of a man who experienced a cluster headache attack following each of 2 sildenafil doses. His symptoms were resolved by adding naproxen to his treatment regimen and changing his ED treatment from 50 mg of sildenafil to 5 mg of vardenafil. To our knowledge, no study has reported cluster headaches triggered by the less commonly used PDE-5 inhibitors, namely vardenafil and tadalafil. Urologists should be cautious in prescribing sildenafil to patients with ED and with a history of cluster headaches. In these patients, they should consider prescribing low-dose vardenafil or tadalafil instead. Failure to recognize sildenafil risks could result in unnecessary headache bouts in patients with a history of cluster headaches.

Your doctor probably based their decision on this research.

Title: Re: Cialis (Tadalafil) for ED - CH interaction
Post by AussieBrian on Feb 11th, 2019 at 11:04pm
Our good mate Hoppy recently quoted this same piece of research on another thread along with the comment:

"Maybe these were the culprit for the beast returning after a 6yr break!"

This monster sure knows how to take away everything we love so much. 

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