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Anybody taking Melatonin way before bed time? (Read 3759 times)
MrsT
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Anybody taking Melatonin way before bed time?
Oct 30th, 2008 at 5:45am
 
In this episode, attacks between 8 and 10 PM seem to be popular for me.  At least in the past few days, I haven't had any wake up visitor, and I'm taking 6 mg of melatonin about 7 PM and again 9 mg before bed.

I started adding the 6 mg shortly after sundown, to boost my melatonin level.  It hasn't prevented the evening attacks though.  I'm thinking about upping the later afternoon/early evening melatonin dose.  So far melatonin hasn't been a "sleep aid" for me at all, but it might have contributed to avoiding attacks in my first REM phase.  I don't know for sure.

Some articles I've read indicated that the bedtime melatonin supplementation may even help with daytime attacks, not just attacks in our sleep.  Since there's no established toxicity level of melatonin (so far), if one doesn't get sleepy with it like me, maybe it's worth experimenting with it at sundown, or even during the day?  Thoughts?
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Agostino Leyre
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Re: Anybody taking Melatonin way before bed time?
Reply #1 - Oct 30th, 2008 at 10:56am
 
I try to take mine at least 2 hours before I plan on sleeping.
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Re: Anybody taking Melatonin way before bed time?
Reply #2 - Oct 31st, 2008 at 12:07am
 
I'm a strong believer in melatonin. It's the only med i continued to take after my last cycle. I don't take it all the time, just when i'm having bouts of insomnia.

The stuff never made me sleepy, but it always seems to help me fall asleep better and i believe it helped me have nearly 4 years PF.

Since my first hit in 4 years, i've been taking it every night again and haven't had another hit, just a few random shadows and 3am wake ups with no pain.

I take it about 30 minutes or so before i go to bed and usually fall asleep pretty easily then. If i don't take it, i can lay awake for hours on a bad night.

Anne
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BMoneeTheMoneeMan
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Re: Anybody taking Melatonin way before bed time?
Reply #3 - Oct 31st, 2008 at 12:18am
 
I am a strong believer in melatonin also.  I take it with benadryl also.

I have found that one hour for me is good.  If I take the pills more than an hour before bed, i find that the sleepyness has worn off. 

Melatonin has been great for me, but it needs to be used with a strict sleep schedule.  I.E., no naps and no staying up late.  When I alter my sleep schedule it spells bad news.  Last week I stayed up til 3am on one night, and it was bad news for me for about 3 days.  Having a regular sleep schedule is very important for me.

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monty
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Re: Anybody taking Melatonin way before bed time?
Reply #4 - Nov 5th, 2008 at 1:30pm
 
I usually take it a half hour before bedtime, and try to set the same bedtime every night if I have some symptoms that I might be going into a cycle. I think it helps me.
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Re: Anybody taking Melatonin way before bed time?
Reply #5 - Nov 7th, 2008 at 12:00am
 
Melatonin is great for a sleep aid especially when your facing attacks. It does seem to lesson them. My neurologist has me take at times 9 to 12 mg when I am suffering attacks, which seems to really help. He doesn't want to me to go over that though. When not suffering I try to stick to around 6mg.
I try to take it an hour before I plan of going to bed.
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fly gas
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Re: Anybody taking Melatonin way before bed time?
Reply #6 - Dec 9th, 2008 at 4:48pm
 
I've used Melatonin forever, does seem to help sleep.

This episode, went to my MD, and he cautioned me against it. Logic is that M works by resetting the sleep cycle, thus its use for long travels. It might not be the best thing to do when you are in a CH episode.

Given the cyclic nature of clusters, I'd have to think there is some correlation between natural and enhanced melatonin levels in the body.

I am not aware of any research in this field, curious if anyone else has run across any. Might just be one of those things where we have to rely on anecdotal reports from other CH sufferers.

Very curious how your daytime experiments pan out, please let us know.

Chris
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MrsT
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Re: Anybody taking Melatonin way before bed time?
Reply #7 - Dec 9th, 2008 at 9:53pm
 
Hi, Chris.  I ended up upping to 9 mg about sundown and 15 mg about midnight.  Honestly I can't say Melatonin has done anything for me.

One thing is that I have no sleep pattern.  While many find it helpful to have a strict sleep schedule, I don't have a sleep pattern to begin with.  I don't know whether that's because my circadian clock is so screwed up or whether my previous work forced me into the habit of "sleep whenever I can" as I often had to be ready to report to work 24/7.  As far as I can remember since childhood, I don't seem to have a concept of a "body clock".  This might be something I could train myself to have, but that's how I've been pretty much all my life.

While on "melatonin at sundown" in high cycle, late-night attacks weren't prevented or eased.  Other than the "right after dinner" sleepiness that I sometimes get anyway, melatonin itself didn't make me sleepy.  The midnight dose never ever made me sleepy a bit, and CH woke me up from the REM phase whether I went to bed at 1 AM or 5 AM.  I added Benadryl, still no change.

My husband took 3 mg out of curiosity.  He's a night person like I am, but his sleep is well scheduled.  He conked out very easily with one 3 mg tablet  Grin.
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Re: Anybody taking Melatonin way before bed time?
Reply #8 - Dec 10th, 2008 at 8:11am
 
As I understand Melatonin, it is most like a switch, resetting your sleep cycle. With travel, when you get there and it is local sleep time, take 3-6-9-12 mg, and it resets you, unlike sleeping pills which whack you to sleep, it allows you to go to sleep, and is said to reset your body clock.
I use it and it seems to work consistently, so previous episodes I have always used it, although I still would wake up numerous time, it did seem to help a little, ergo, ANYTHING that might promote sleep.
My doc, the MD questioned the idea of resetting the body clock every single day. With a number of studies that suggest the same part of the brain that sets the circadian rhythm is also involved in CH, I decided to drop the melatonin this cycle.
For some reason, this cycle, Zomig pill form seems to be working. 1/4 of a 5 mg pill, 3hours before bedtime, then one quarter just before sleep. 7 nights I've tried this one, I've slept through, this after weeks of 2-3 clusters a night.
I find this odd, because last cycle I tried one Zomig pill, and it shot the headache to a solid ten, the only ten in the whole episode, never touched another one. This Z experiment started after reading some of the posts wrt lowered doses and efficacy of Zomig for some, figured I'd try a 1/4 just to see.
After 36 years of CH, all I've learned is to keep experimenting. Who knows what will end an episode, but my experience is that individual headache remedies usually either work or don't work, and I'm aggressive to drop one and try a new one. I do experiments on myself I wouldn't recommend to anyone, but Zomig and Pelpax have been working this time, oxygen half the time, hot showers work almost 100% for me, sometimes head massages, especially around the ear, a real mish mosh of stuff.
Still, when one doesn't work, and it sounds like melatonin isn't working, time to try something else, hit your doc for some new scripts, go through some old threads and see what has worked for others, just keep fighting the good fight.
A lot of good info on this site, I like the posts where people have actually tried something that worked for them. There's one on chugging a can of Pepsi, sounds bizarre, but between caffeine, CO2, and other ingredients, sounds safe, worked for someone else, and if nothing else is working, certainly don't see a down side.
BTW, if you do drop melatonin, curious what the effect would be. I've had experiences where dropping a drug seemed to help, y'never know.
Best of luck with your headaches,
Chris
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monty
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Re: Anybody taking Melatonin way before bed time?
Reply #9 - Dec 10th, 2008 at 11:48am
 
Yes, melatonin is a switch involved in sleep cycles. But it also has effects on serotonin metabolism - in the short term, it tends to block many effects of serotonin.  I have seen some research suggesting that melatonin blocks or downregulates the 5-HT2 serotonin receptors (the same ones affected by clusterbusters, kudzu and olanzapine).

Some research has shown that clusterheads do not have a normal night time peak of melatonin, and that this is true even for episodics who are not in cycle.  It may be a permanent bug feature for us, while the average person indeed probably would not want to take it every night.
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« Last Edit: Dec 10th, 2008 at 11:52am by monty »  

The outer boundary of what we currently believe is feasible is far short of what we actually must do.
 
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MrsT
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Re: Anybody taking Melatonin way before bed time?
Reply #10 - Dec 10th, 2008 at 12:30pm
 
fly gas wrote on Dec 10th, 2008 at 8:11am:
BTW, if you do drop melatonin, curious what the effect would be. I've had experiences where dropping a drug seemed to help, y'never know.

I dropped melatonin already.  No change in my sleep pattern (or no pattern) whatsoever.  Either real low cycle or I'm on the way out, and I've been off Verapamil as well.  I want to stay away from pharmaceuticals as much as I can especially triptans unless I'm in high cycle and desperate.  Fortunately I haven't had suicidal 9-10 at least 10 years.  Since I dropped melatonin and Verapamil shortly thereafter, O2 has been it.  I still get a wake up visit almost daily but very mild and really no big deal.

I was also taking 250 mg magnesium for a while.  I couldn't handle a 250 mg tablet twice a day at all (my diet is already high in magnesium), and I decided not to mess with my normal daily diet.
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Re: Anybody taking Melatonin way before bed time?
Reply #11 - Dec 10th, 2008 at 9:24pm
 
I take it about an hour before bed.  I continue taking it between cycles and will take it probably the rest of my life.  I have not had it help with daytime attacks, only nighttime ones.
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Re: Anybody taking Melatonin way before bed time?
Reply #12 - Dec 18th, 2008 at 12:33am
 
I try to take melatonin as often as possible since it does seem to help. When I going through a cluster phase my Dr. prescribed Ambiem which seems to really help with night time clusters. At least I am getting some sleep!
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« Last Edit: Dec 18th, 2008 at 12:34am by neetnut »  
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Re: Anybody taking Melatonin way before bed time?
Reply #13 - Dec 18th, 2008 at 11:33am
 
As a suggestion, be very, very cognizant of the timing of when you take it.

I've been doing Zomig 5mg pills where two 1/4 doses before bed has killed the nighttime clusters, with the daytimes just zipping along, although not that bad, 4-6's. Pretty well established pattern, but I tried a 1/4 pill a few days ago on my one o'clock daytime visitor, and it didn't do anything, then the 3 o'clock was a ripper, first real 8 of this cycle, and even after the bed time dose, I got night time clusters and a morning wakemeup.

Now 3 days later, back to a good night's sleep with the quarter/quarter doses, figure if I can sleep, I am WAY ahead, but just be careful, there is so much we don't know, circadian rhythms, seasonal stuff and the like.
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Re: Anybody taking Melatonin way before bed time?
Reply #14 - Dec 27th, 2008 at 11:52pm
 
Does anyone know if there are any contraindications for taking melatonin?

I believe I'm still chronic (my def'n, not IHS def'n) - verap and lithium combo controls the non-high-cycle, with just rogue hits. Now I seem to be in high cycle.

Doc won't increase the verap (480/day); can't tolerate more lithium (750/day). So I'm thinking maybe melatonin is an option.

Lizzie
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Re: Anybody taking Melatonin way before bed time?
Reply #15 - Dec 28th, 2008 at 10:14am
 
A bunch of contraindications, esp with mood drugs, BP drugs and the like,
also the standard ones, pregancy, and you don't want to fly your 747 jet with a good slug of melatonin in you..
While I don't know if there are any researches thus, melatonin works on the circadian rhythms, which certainly may have some interesting (profound?) workings with CH. Check with the doc, but there are enough reports on the positives with melatonin in the CH.com posts, it is sure worth a look.
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Re: Anybody taking Melatonin way before bed time?
Reply #16 - Jan 6th, 2009 at 5:38pm
 
I ordered one of the SAD lights to try to help with my crappy moods now that winter is upon us. Hopefully it will help with the CHs as well. I'm using it for half an hour as soon as I wake up in the morning. I've only used it for about a week so far and haven't noticed much of a difference yet.
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