Supposed to be faster and stronger than imitrex.  Anyone know anything about it and if it will help with CH.

My doctor can get me samples if it is something I should try.

It's a combination being marketed for migraine. While it is Imitrex, being in a pill form it will be less useful for Cluster which needs the rapid onset of injection (although some find the pill helpful). The second med of the OTC naproxen--a pain med which has no application for CH.

My pharmacist said it would be basically the same thing as taking Imitrex plus some Ibuprofen, and it is more helpful for typical migraines.

jmc1106 wrote on Nov 29^th, 2008 at 4:21pm:



OK, if its like imitrex and ibuprophen then it should help the same as trex by itself, right?

See, my doctor can get samples of this and free abortives are not something I would say no to.

TREXIMET is the only migraine treatment to combine these 2 medicines — IMITREX ( sumatriptan) and prescription-strength naproxen sodium (an NSAID) — in one ...
Multimedia File Viewing and Clickable Links are available for Registered Members only!!  You need to or

Important information about Treximet
Do not take more than 2 Treximet tablets in 24 hours.

You should not use Treximet if you are allergic to sumatriptan (Imitrex) or naproxen (Aleve, Anaprox, Naprosyn), or if you have a history of asthma or allergic reaction caused by aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs).
Sumatriptan is a headache medicine. It is believed to work by narrowing the blood vessels around the brain. Sumatriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms. Naproxen is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Naproxen works by reducing hormones that cause inflammation and pain in the body.

Do not take Treximet if you have liver disease, uncontrolled high blood pressure, or a history of heart disease, angina (chest pain), blood circulation problems, heart attack, stroke, or heart bypass surgery.

Do not take Treximet if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), selegiline (Eldepryl, Emsam), or phenelzine (Nardil) in the past 14 days. Do not take Treximet within 24 hours after taking any of the following medications: almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), sumatriptan (Imitrex), or zolmitriptan (Zomig), or ergot medicine such as methysergide (Sansert), ergotamine (Ergomar, Ergostat, Cafergot, Ercaf, Wigraine), dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), ergonovine (Ergotrate), methylergonovine (Methergine).
Before taking Treximet
You should not use Treximet if you are allergic to sumatriptan (Imitrex), naproxen (Aleve, Anaprox, Naprosyn), or if you have a history of asthma or allergic reaction caused by aspirin or other NSAIDs such as ibuprofen (Motrin, Advil), diclofenac (Cataflam, Voltaren), etodolac (Lodine), indomethacin (Indocin), ketoprofen (Orudis), and others.
Do not take Treximet if you have:

liver disease;

untreated or uncontrolled high blood pressure; or

a history of heart disease, angina (chest pain), blood circulation problems, heart attack, stroke, or heart bypass surgery (also called coronary artery bypass graft, or CABG).

Do not take Treximet if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or phenelzine (Nardil) in the past 14 days. Do not take Treximet within 24 hours after taking any of the following medicines:
almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), sumatriptan (Imitrex), or zolmitriptan (Zomig); or

ergot medicine such as methysergide (Sansert), ergotamine (Ergomar, Ergostat, Cafergot, Ercaf, Wigraine), dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), ergonovine (Ergotrate), methylergonovine (Methergine).

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before taking Treximet, tell your doctor if you have:

high blood pressure;

congestive heart failure;

epilepsy or other seizure disorder;

liver disease;

kidney disease; or

coronary artery disease (or risk factors that include diabetes, menopause, smoking, being overweight, having high blood pressure or high cholesterol, having a family history of coronary artery disease, being older than 40 and a man, or being a woman who has had a hysterectomy).

FDA pregnancy category C. Treximet may be harmful to an unborn baby. Tell your doctor if you are pregnant before you take this medication. Taking naproxen during the last 3 months of pregnancy may result in birth defects. Do not take Treximet during pregnancy without your doctor's advice. Treximet can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.



The naproxen sodium content will not alow you to use it more than twice a day, My doc lets me do 3 vials SC Injection  in 24hrs* so if you need it more than twice in a day you will have to supliment with Imitrex alone.

*Add; I have never done this and the 1 time I did 2.5 in half vial shots I thought my heart was going to pop. I hardly touch it any more because of that and the rebound attacks. I get very poor pofomance for the risk but if you like it GSK likes you as an outstanding coustomer!

Rolo..

Quote:


Ta-Da!!!!!!!!!  by George he's got it. GSK's patent runs out shortly and they are scrambeling all over the place to keep those bucks coming in.  I think it's called re-formulating.  Lets add a non-useful ingredient and we can get more fools to keep buying our product instead of others who can produce it generically for less.   Or something like that.

if it looks like a duck, sounds like a duck, walks like a duck.
it damn well may be a duck.  (gimmick drug)

The doc's should have a hefty supply of samples to get ya hooked.
Just like the drug pushers they are.
I agree with Karl. Looks like a duck
the bb

I took some samples last week and they didnt act fast like the injection but they were faster then the reg imitrex pill, seemed to be about as fast as the nasel spray..  The one thing that I did like about it was that it seemed to last allot longer and didnt wear off as fast as the injection does, and allowed for a better sleep between attacks...

Quote:


I don't have that problem.  I honestly don't know any doctors that are drug pushers.  In fact is that the doctors I go to only accept samples for their patients who cant afford them.... and people like me.

I guess I could grab a few samples for an emergency.

My doc didn't have samples, but did have a $25 voucher which made it only $10 for the nine pills. (I have Cigna, too). I don't know how many of those vouchers I would be able to use, but reading the literature  that was enclosed (does anyone do that any more), it says it isn't for those who have finished menepause. I think I'll just stick with the Imitrex shots.