Well, my clusters should be coming anytime, but I'm preparing for the beast this time. I've been researching. Some other things that might help I'd like to share:
I'm on Depakote for something else, but my doctor said there's a link to Depakote and clusters...we'll find out.
Also, I looked it up, and low doses of psilocybin and/or salvia claims to put clusters in remission better than any prescription or non-prescription drug, including O2. I refuse to let the bastard bring me down this year! Hope all is well with everyone and you're not in too much pain.
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In 2004, after reading numerous accounts testifying as to their ability to send cluster headaches into complete remission at low, regular, non-escalating doses, Wiseman tried psilocybin mushrooms for the first time. In the United States psilocybin, LSD, mescaline, DMT, and virtually every other entheogen are Schedule 1 substances with no recognized medical use.
But Wiseman says that the psilocybin mushrooms not only worked, they worked better than any prescription or non-prescription remedy she'd tried: The first time she took the psilocybin the headaches went away, completely, for three days.
Then, a month of relief without taking anything other than psilocybin. She tested herself in that time period, taking the mushrooms only when she felt the headaches coming on. By the end of the month, she was able to take psilocybin once every 60 to 90 days, experiencing complete remission without having to elevate the dose.
Most cluster headache sufferers only require sub-hallucinogenic doses to achieve remission. Wiseman's case was consistent with this finding, in that every time she's taken psilocybin it's been at sub-hallucinogenic levels, and, at most, "makes the colors on the Home and Garden channel very pretty."
"I had little to no quality of life prior to that," Wiseman says. "I was afraid to do things. I wasn't able to work. We couldn't go on vacations. Whenever I went to a soccer tournament for my kids, I had to run to the car or go hide because I was in pain. I just wished we could go home. How awful is that?"
Anita's experience and turnaround on hallucinogens isn't unusual in CH circles. It's estimated by the Clusterbusters organization that 80 percent of the cluster headache sufferers who try psychedelics find near-complete relief and the attendant improved quality of life.
Though Dr. Sewell — who conducted the first comprehensive case series on cluster headache suffers who use hallucinogens therapeutically — and other researchers don't know why psilocybin, LSD, and other entheogens work, their preliminary research suggests that some people experience remarkable therapeutic effects, if illegally.
There is a caveat, says Sewell, and that is that there have been no randomized placebo-controlled trials. While Sewell is in the final stages of a large study looking into the efficiency of LSA — a natural LSD analogue found in Morning Glory and Hawaiian baby woodrose seeds — against cluster headaches, it's an independent effort.
"It's hard to imagine a company interested in marketing a drug that's long out of patent and only has to be taken once every three or four months," says Dr. Sewell.