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Our screwed up hypothalmus and depression (Read 7779 times)
Jimi
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Re: Our screwed up hypothalmus and depression
Reply #25 - Jul 1st, 2010 at 3:46pm
 
My neuro told me once..."Jim, you look like you are depressed. I said.."I have cluster headaches and I am in high cycle, wouldn't you be depressed?

He laughed and said yeah I guess I would.

But I agree with Lettuce (I wish you had a different name lol) When you are clinically depressed you can't just snap out of it or will it away. It is an entirely different animal.
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« Last Edit: Jul 1st, 2010 at 3:48pm by Jimi »  

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Lettucehead
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Re: Our screwed up hypothalmus and depression
Reply #26 - Jul 1st, 2010 at 6:09pm
 
Brew wrote on Jul 1st, 2010 at 2:13pm:
jayhedges wrote on Jul 1st, 2010 at 2:06pm:
CH sufferers by defintion are prone to depression.

I beg to differ. While the incidence of depression may be higher amongst CH sufferers, you cannot say that being prone to depression is part of the definition of CH.


I don't think that Jay was implying that depression is part of the definition of CH. 
My interpretation of his post was that with the chronic severe pain, lack of control, lack of sleep, social isolation, etc, of CH comes an understandable element of despair, helplessness, hopelessness - these issues then lend themselves to the development of depression. 

I think one would find a similar domino cascade in many chronic pain conditions - it is not that depression causes CH, but that the relentless 'side effects' of CH causes depression...

And, Jimi, my name is Kirsten...   Wink
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Listen, and understand. That terminator is out there. It can't be bargained with. It can't be reasoned with. It doesn't feel pity, or remorse, or fear... 'The Terminator' AKA CH
 
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Guiseppi
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Re: Our screwed up hypothalmus and depression
Reply #27 - Jul 1st, 2010 at 8:15pm
 
Phew....Kirsten.....that rolls off the fingers much easier then Letuce! Grin
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"Somebody had to say it" is usually a piss poor excuse to be mean.
 
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Re: Our screwed up hypothalmus and depression
Reply #28 - Jul 2nd, 2010 at 3:40am
 
My sufferer is taking effexor.  I took it at one point because a doctor I had thought I had fibromyalgia due to a family history.  I have a mother and two aunts that have been diagnosed with this and I may very well have it.  I quit taking it because the doctor told me I would have to take it the rest of my life.
I have noticed that when my boyfriend forgets to take his, there is a noticeable side effect. 
I have not been able to observe a linkage between the med and the CH's as of yet.  When I told him I had joined this site, he offered to have me go with him to see his headache doc.  This is one of many questions I have for the doc. 
If anyone has any feedback on this, I would appreciate it!  I am trying to find ways to lessen the attacks and conquer the "beast"!
FYI, he has a oxygen tank and is on verapimil and taga...something(can never rememeber what this one is!).  The verapamil seems to help but tanks the sex drive.  I notice a definite moos shift as he starts these two meds up each cycle.
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Re: Our screwed up hypothalmus and depression
Reply #29 - Jul 2nd, 2010 at 5:38am
 
Quote:
I notice a definite moos shift as he starts these two meds up each cycle.


This is something he should talk to his doctor about if the meds are a cause of mood shifts.  On the other hand the cause could just be the CH and the fact he knows what kind of HELL he's in-for for the next few weeks or months depending on how long his cycle lasts. 

You should have him join the site as well.  It may offer him something he doesn't know or at least some added support we all need at times.

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Re: Our screwed up hypothalmus and depression
Reply #30 - Jul 2nd, 2010 at 8:02am
 
Shell wrote on Jul 2nd, 2010 at 3:40am:
I have noticed that when my boyfriend forgets to take his, there is a noticeable side effect. 


Effexor has a reputation as a pretty good med for depression, but it also has a reputation as a med that can be hard to stop because of side effects.  Often when people stop taking effexor abruptly they can have some temporary mood lability, lightheadedness, dizziness, even some tingling in their extremities - these are all temporary symptoms and not particularly dangerous - just uncomfortable.  Often people have to wean off of effexor very very slowly - i.e. go from 225mg to 150mg for several weeks to 75mg for several weeks to 75mg every other day for several weeks, then stop.  How fast you can wean depends on how uncomfortable you find the weaning side effects...
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Listen, and understand. That terminator is out there. It can't be bargained with. It can't be reasoned with. It doesn't feel pity, or remorse, or fear... 'The Terminator' AKA CH
 
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Guiseppi
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Re: Our screwed up hypothalmus and depression
Reply #31 - Jul 2nd, 2010 at 9:25am
 
The verapamil seems to help but tanks the sex drive.

A common side effect of Verapamil for many. For me it wasn't a reduction in the DESIRE to, just the ABILITY. Like the beast hasn't taken enough away he wants to deprive me of that too! Undecided

Joe
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"Somebody had to say it" is usually a piss poor excuse to be mean.
 
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wimsey1
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Re: Our screwed up hypothalmus and depression
Reply #32 - Jul 6th, 2010 at 8:45am
 
Yeah, sorry to say I understand Joe. And if that ain't cause for depression I don't know what is...oh yeah, the pain, and the side effects, and.....well, you know. Blessings! lance
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Re: Our screwed up hypothalmus and depression
Reply #33 - Jul 6th, 2010 at 9:40am
 
Guiseppi wrote on Jul 2nd, 2010 at 9:25am:
The verapamil seems to help but tanks the sex drive.

A common side effect of Verapamil for many. For me it wasn't a reduction in the DESIRE to, just the ABILITY. Like the beast hasn't taken enough away he wants to deprive me of that too! Undecided

Joe


Maybe you could consider growing some Bishops Hat (epimedium grandiflorum) in your flowerbed. seems to work wonders for goats, and people too.

(edited for spelling)
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« Last Edit: Jul 6th, 2010 at 10:14am by Arde »  

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Kate in Oz
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Re: Our screwed up hypothalmus and depression
Reply #34 - Jul 6th, 2010 at 10:41am
 
It has taken me a while to get around to reading these posts because I tend to avoid anything to do with depression - the reason being that it frightens me.  Silly I know.

Kat I'm sorry to hear you are hurting so much.  I wish you all the best for your doctors appointment and hope that you get the help you need.  The only advice I can offer is that 'this too shall pass'.  Hang in there, don't give up....take each day as it comes, I'm sure one day the sun will come out and you will start to feel better.  And don't be affraid to post here, no one is going to judge you!  This is a support site after all Smiley

I find it interesting to read of the link between CH, depression and chronic pain.  Not just that pain causes depression, but that they stem from similar area of the brain.  I have suffered from depression on and off since I was a teenager.   In 2001 I took a near fatal overdose and ended up on life support for three days.  Having had depression before I thought I would get through it... but I gave up too soon.  I had recently been diagnosed with fibromyalgia and my CH was driving me insane!! - still undiagnosed.

But here I am today, very happy to be alive, now a mum, and life is so much better.  When I feel myself falling apart I actively work on my attitudes, get out, take a daily walk, talk to people etc etc and thankfully it passes.

Thanks for posting the article, very interesting.

Kate
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Re: Our screwed up hypothalmus and depression
Reply #35 - Jul 8th, 2010 at 8:16am
 
Kate in Oz wrote on Jul 6th, 2010 at 10:41am:
It has taken me a while to get around to reading these posts because I tend to avoid anything to do with depression - the reason being that it frightens me.  Silly I know.



But here I am today, very happy to be alive, now a mum, and life is so much better.  When I feel myself falling apart I actively work on my attitudes, get out, take a daily walk, talk to people etc etc and thankfully it passes. Kate   


No, not silly Kate. Who likes to talk about depression? It's depressing, or can be. The point is, you are very right about attitudes and the effect the right mindset can have on helping us cope. It isn't just a psychosomatic thing; it is a complex psycho-soma interaction. The way we think, our "self-talk," and our attitudes effect our brain and our brain effects neuroreceptor/transmitters.

Just being here has helped me tremendously. Not just for the practical advice, although that's been a goldmine, but because being supported and being in support of others has a positive effect all by itself.

Thanks for jumping in and being so open, Kate. I was hoping you'd respond. lance
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Re: Our screwed up hypothalmus and depression
Reply #36 - Jul 8th, 2010 at 9:48am
 
Awesome post Kate, NOTHING speaks like real life experiences. So glad you're in a happy place now. Smiley

Joe
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Re: Our screwed up hypothalmus and depression
Reply #37 - Jul 8th, 2010 at 1:48pm
 
Depression is one word that was often used in my childhood to describe a passing feeling which was, still, more severe than sadness. Then came my university years and flatmate, who was diagnosed with severe depression.

The same flatmate saw me when my second cycle got me so down that she said to me: "I've never seen anyone who is that depressed", and she meant it. Since then I've been through two depression cycles and few one-off hits, which brought me so down that it worried me.

Now things are much better, but who knows? I found out that both my grandmother and father went through depression-like bouts, which could naturally make me a bit more vulnerable to get such feelings than someone else. Knowing that has made things easier for me.

I also know where depression can lead. My boyfriend's father killed himself because of it, my flatmate has thought about it on several occasions. When/if those darker feelings begin to arrive on my horizon I can be more prepared now.

Still, it does help me in great deal that I told my partner about this side of ch before he told me about his father....

Sanna
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Re: Our screwed up hypothalmus and depression
Reply #38 - Jul 8th, 2010 at 1:54pm
 
Well done, Sanna. Like CHs, depression works its evil in silence. Yes, it is somatic too, but keeping things up front and out in the open, allows supporters to really support, and not just wish they could do something to help. And knowing you are vulnerable, and when another bout may hit (hey, just like CHs!) is a great defensive weapon. May you stay pain and depression free! lance
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Re: Our screwed up hypothalmus and depression
Reply #39 - Jul 9th, 2010 at 9:25am
 
Smiley

This place really has been a godsend to so many of us.  Just knowing that you're not alone in suffering is a tremendous help!  And having a place to vent/moan etc when life gets us down is great - especially when others who no doubt care, really struggle to understand.

Again, thanks for such an interesting/helpful topic!

Kate



Kat you are in my thoughts, I hope you are keeping well and looking after yourself.
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Re: Our screwed up hypothalmus and depression
Reply #40 - Jul 14th, 2010 at 9:43am
 
something interesting you may want to read.
diagnostic criteria for depression.

Major Depressive Episode

A. Five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure.

Note:  Do note include symptoms that are clearly due to a general medical condition, or mood-incongruent delusions or hallucinations.

(1) depressed mood most of the day, nearly every day, as indicated by either subjective report (e.g., feels sad or empty) or observation made by others (e.g., appears tearful). Note: In children and adolescents, can be irritable mood.

(2) markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day (as indicated by either subjective account or observation made by others)

(3) significant weight loss when not dieting or weight gain (e.g., a change of more than 5% of body weight in a month), or decrease or increase in appetite nearly every day. Note: In children, consider failure to make expected weight gains.

(4) insomnia or hypersomnia nearly every day

(5) psychomotor agitation or retardation nearly every day (observable by others, not merely subjective feelings of restlessness or being slowed down)

(6) fatigue or loss of energy nearly every day

(7) feelings of worthlessness or excessive or inappropriate guilt (which may be delusional) nearly every day (not merely self-reproach or guilt about being sick)

(8) diminished ability to think or concentrate, or indecisiveness, nearly every day (either by subjective account or as observed by others)

(9) recurrent thoughts of death (not just fear of dying), recurrent suicidal ideation without a specific plan, or a suicide attempt or a specific plan for committing suicide

B. The symptoms do not meet criteria for a Mixed Episode.

C. The symptoms cause clinically significant distress or impairment in social, occupational, or other important areas of functioning.

D. The symptoms are not due to the direct physiological effects of a substance (e.g., a drug of abuse, a medication) or a general medical condition (e.g., hypothyroidism).

E. The symptoms are not better accounted for by Bereavement, i.e., after the loss of a loved one, the symptoms persist for longer than 2 months or are characterized by marked functional impairment, morbid preoccupation with worthlessness, suicidal ideation, psychotic symptoms, or psychomotor retardation.

Major Depressive Disorder


Single Episode

A.  Presence of a single Major Depressive Episode

B.  The Major Depressive Episode is not better accounted for by Schizoaffective Disorder and is not superimposed on Schizophrenia, Schizophreniform Disorder, Delusional Disorder, or Psychotic Disorder Not Otherwise Specified.

C. There has never been a Manic Episode, a Mixed Episode, or a Hypomanic Episode. Note: This exclusion does not apply if all the manic-like, mixed-like, or hypomanic-like episodes are substance or treatment induced or are due to the direct physiological effects of a general medical condition.

Recurrent

A.  Presence of two or more Major Depressive Episodes.

      Note: To be considered separate episodes, there must be an interval of at least 2 consecutive months in which criteria are not met for a Major Depressive Episode.

B.   The Major Depressive Episodes are not better accounted for by Schizoaffective Disorder and are not superimposed on Schizophrenia, Schizophreniform Disorder, Delusional Disorder, or Psychotic Disorder Not Otherwise Specified.

C.  There has never been a Manic Episode, a Mixed Episode, or a Hypomanic Episode. Note: This exclusion does not apply if all the manic-like, mixed-like, or hypomanic-like episodes are substance or treatment induced or are due to the direct physiological effects or a general medical condition.

source
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Quote:
The symptoms are not due to the direct physiological effects of a substance (e.g., a drug of abuse, a medication) or a general medical condition (e.g., hypothyroidism).
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Oh come on!it's just water.It can't be that bad!
 
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wimsey1
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Re: Our screwed up hypothalmus and depression
Reply #41 - Jul 15th, 2010 at 8:42am
 
Black, I do find it interesting. I also am a bit confused as to why you posted it here. The original article was about the physiology behind depression, not the symptoms, and the role the hypothalmus plays in the symptomatic appearance of depression. The DSMR (Diagnostic and Statistical Manual Revised) gives criteria (generally for billing purposes) of a clinical diagnosis, but is not a "leading edge" for research purposes. It is constantly under examination as new research comes to light and as such its finding, and its publication, revised.

Having said that, you seem also to be taken with the idea that we cannot be depressed because we have a medical disorder, since a medical disorder by diagnostic criteria cannot be the cause of depression. Hmmm...we said the hypothalmus, through a complex feedback mechanism, is the center of neurotransmitter/neuroreceptor hormones that are identified as contributory to depression, and it is probably the hypothalmus that is involved in the triggering of cluster attacks. If A, then B...the same organ which triggers depression and controls hormones related to depression, also triggers CH attacks. If it is faulty in one area, then it is logical to question its faultiness in the other area as well.

And whether or not circumstantial criteria can be considered when making a determination of clinical depression is not as settled as you make it out. Here is an excerpt from the university of Berkeley:

Stress: Psychological and environmental stressors can contribute to a depressive episode. Common stressors among college students include:


academic demands
transitions-re-entry to school, being new to Berkeley
balancing school, work, family, social life
financial responsibilities or worries
family concerns
social isolation
difficulties in relationships with friends and romantic partners
being on one's own in a new environment
exposure to new ideas, new people, and temptations
awareness of sexual identity and orientation
preparing for life after graduation, career decision-making

A major loss, chronic illness, relationship problems, work stress, family crisis, or unwelcome life changes can often trigger a depressive episode, even in individuals without a family history or genetic predisposition.

All of the above in bold can accompany the Clusterhead, especially chronics. They therefore can "act as a trigger" for a depressive episode.

Denying depression cannot cure it. It is biological in basis and must be addressed as such.

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Sorry to have made this so technical, but you opened the door. Blessings! lance
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Re: Our screwed up hypothalmus and depression
Reply #42 - Aug 15th, 2010 at 9:56am
 
I have always been intrigued by the possible connection between depression/serotonin and CHs.

All I know is that mine started when I developed depression and began taking SSRIs..................
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Re: Our screwed up hypothalmus and depression
Reply #43 - Aug 16th, 2010 at 7:39am
 
I read somewhere, sometime ago (sorry to be so vague about it but maybe someone has a more specific reference) that CH's may be preceded by a serotonin storm...something which can by itself be pretty deadly. Any input on this? lance
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