Arlene,
The following link will take you to the post I started last December on the anti-inflammatory regimen... Read all the pages to see what others are reporting after starting this regimen.
I've kept a running tally on the efficacy of this regimen... To date, the raw efficacy of this regimen as a cluster headache preventative is 75% with a ±15% margin of uncertainty.
To put that in perspective, studies have shown that placebos are effective in 50 or 60 percent of subjects with certain conditions, e.g., "pain, depression, some heart ailments, gastric ulcers and other stomach complaints."
The Cluster Headache survey many of us took in 2008 with 1134 responding gave some interesting statistics on the effectiveness of the leading preventative verapamil.
Of the 725 CH'ers who had taken or who were presently using verapamil as a preventative for their cluster headaches, only 361 (49.79%) rated it as effective... and nearly all complained of side effects...
When you put all that together you'll see that the efficacy of this regimen exceeds the highest possible placebo effect, it's clearly more effective than verapamil, and it has no adverse side effects... Draw your own conclusions...
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In short, this regimen combines the anti-inflammatory properties of Omega 3 Fish Oil with similar properties of vitamin D3. In order to obtain the full benefits of vitamin D3, most nutritionists and physicians who treat patients deficient in vitamin D3 recommend supplementing with calcium, magnesium and zinc.
As neurogenic inflammation is part of the cluster headache syndrome and our cluster headaches respond to steroids like prednisone, my thinking was this regimen could be a less invasive alternative to prednisone as it has no adverse side effects and it's actually healthy for us to boot.
The second part of this regimen is actually a buffer that's formed when the calcium citrate is combined with citric acid from lemonade, limeade or any juice high in citric acid. The buffering action elevates the pH of stomach contents and this eventually elevates arterial pH making it less acidic. An elevated arterial pH tends to stimulate vasoconstriction that makes the cluster headache triggering mechanism less effective.
I'd been chronic since 2004 and had used calcium citrate and lemonade in the past to break high cycles and to shorten abort times with oxygen therapy at flow rates that support hyperventilation... I'd also used Omega 3 Fish Oil to control cholesterol and found it has a pleasant side effect of reducing the frequency of my CH.
Last year after looking over my logs, I found the calcium citrate and lemonade or margarita mix... worked best in the summer time and that started me thinking vitamin D3 was playing a role.
When I put it all together last October after researching optimum vitamin D3 dosing, all I was expecting was a reduction in the frequency of my CH and shorter abort times with oxygen therapy... What I didn't expect was a complete cessation of my cluster headaches after two days on this regimen... I've been pain free ever since...
Hope this helps...
Take care,
V/R, Batch