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Vitamin D3 and anxiety (Read 5412 times)
CrankieFrankie
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Vitamin D3 and anxiety
Dec 18th, 2012 at 8:51am
 
I've been taking 20,000iu of vitamin d3 for the past week and I've noticed an increase in my anxiety and heart palpitations. Has anyone else had this side effect? The D3 was working for awhile but now has stopped completely.
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Batch
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Re: Vitamin D3 and anxiety
Reply #1 - Dec 18th, 2012 at 1:16pm
 
Hey Frankie,

Hmmm... What you're reporting is news to me...  That's a new side effect... if that...  To my knowledge, no other CH'ers have reported similar symptoms...

Are you taking calcium and the rest of the vitamin D3 cofactors?  If so... at what doses?

Are you taking any other meds or drinking more than a couple cups of coffee?

If you feel that uncomfortable... stop taking the entire regimen... and see what happens.

Take care, hang in there, and keep us posted...

V/R, Batch
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CrankieFrankie
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Re: Vitamin D3 and anxiety
Reply #2 - Dec 18th, 2012 at 1:27pm
 
I've been taking Calcium and Magnesium at night, which has gotten rid of the night time hits completely. After posting that message, I was doing some research and came across the following article (and other similar ones). I've read that sometimes taking increased doses of Vitamin D "uses up" more magnesium in the body and can create side effects of a magnesium deficiency. These side effects can include Insomnia, Heart Palpitations, Anxiety and Jitteriness.

So I'm assuming that I'm just not taking enough Magnesium to counteract the high doses of Vitamin D. I am going to increase my intake of magnesium for the next few days and see if it makes a difference.

Vitamin D, just like all other nutrients, works in harmony with several other nutrients to perform its many functions. Most importantly, vitamin D requires and 'uses up' magnesium to convert from supplements or sun into its active form in the blood. As such, it is a big mistake to simply take large doses of Vitamin D without taking the need for magnesium into consideration.

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"I close my eyes, I tell myself to breathe and be calm. I know you feel like you are breaking down. I know that it gets so hard sometimes. Be calm."
 
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Batch
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Re: Vitamin D3 and anxiety
Reply #3 - Dec 18th, 2012 at 1:59pm
 
Frankie,

Your explanation works for me...

Take care and please keep us posted.

V/R, Batch
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Re: Vitamin D3 and anxiety
Reply #4 - Dec 18th, 2012 at 3:24pm
 
Frankie,

20,000 IU a day????  That just seems like alot. does the human body even absorb that much D3 in a day?

I think your getting a lil high on those dose levels. Also I wonder if a body would even absorb 20,000 IU if you were standing naked on the equator?

Don't get me wrong, i take D3 daily 5000 Iu. And i do believe that combined with magnesium, vitamin D3 does help with CH. But i also believe at those doses your either peeing most of it out, or taking some risks on some serious side effects.

Coach Bill.
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« Last Edit: Dec 18th, 2012 at 3:45pm by coach_bill »  

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CrankieFrankie
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Re: Vitamin D3 and anxiety
Reply #5 - Dec 18th, 2012 at 3:37pm
 
I had just worked up to the 20,000 level in the past 2 days. The plan was to take that amount for a week then reduce back to 10,000 a day. My hits have been extremely brutal the week before and I wanted to try to increase my levels as much as possible. I was taking each dosage with full meals so I'm guessing most of it was being absorbed. Based on all of the reading that I had done on the regimen, I figured I would be safe at those doses for a short amount of time.
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Re: Vitamin D3 and anxiety
Reply #6 - Dec 18th, 2012 at 3:40pm
 
coach_bill wrote on Dec 18th, 2012 at 3:24pm:
Frankie,

20,000 IU a day????  That just seems like alot. does the human body even absorb that much D3 in a day?

I think were getting a lil high on some these dose levels. Also I wonder if a body would even absorb 20,000 IU if you were standing naked on the equator?

Don't get me wrong, i take D3 daily 5000 Iu. And i do believe that combined with magnesium, vitamin D3 does help with CH. But i also believe at those doses your either peeing most of it out, or taking some risks on some serious side effects.

Coach Bill.

Quite the opposite, coach. I took 20,000 iu per day with a loading dose of 50,000 iu once per week for two months. I now take 10,000 iu per day every day along with zinc, magnesium, calcium, fish oil, and some other trace stuff found in a men's multi-vitamin.

It takes some people a LONG time to get their 25(OH)D serum levels up to a point where CH is prevented. I haven't had to bust since April.
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Re: Vitamin D3 and anxiety
Reply #7 - Dec 18th, 2012 at 3:52pm
 
I took 10,000 IU for about 2-3 days up from 2,000 IU. I did notice I was feeling very high strung, and i lost most of my appetite so i went down to 5000 iu and have been there for 3 years. I guess everyone is different on the inside. I did reword my post as to not offend anyone.

7 months?  NICEEEEE!!!!!
Coach Bill
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Batch
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Re: Vitamin D3 and anxiety
Reply #8 - Dec 18th, 2012 at 7:21pm
 
Coach,

I've worked with several CH'ers who took 50,000 IU/day vitamin D3 under a physician's supervision for two weeks and a couple for up to a month.  None of them had any adverse effects...  nor were their 25(OH)D serum concentrations out of the normal reference range...

Quite the contrary, all reported feeling better than they've felt in many years...

I suspect the "high" feeling you experienced taking vitamin D3 supplements was your body running as it was designed to run... with plenty of natural cutaneous vitamin D3 from the UVB in sunlight...

Many of us experience an increased level of invigoration, energy and sense of wellness after a few days to a week on vitamin D3 doses of 10,000 to 20,000 IU/day.

20,000 IU/day of vitamin D3 is also very safe...  It's equivalent to a half hour of summer sun clad in a bathing suit without any sun block..

Vitamin D3 intoxication is rare.  For most of us it would required 50,000 to 100,000 IU/day for over two months... It can occur at lower doses but this is usually associated with hyperparathyroidism...  too much PTH...

The symptoms of vitamin D3 intoxication are the opposite of feeling high...  Clinically, this condition is characterized by total calcium serum concentrations above the normal reference range...

Regarding pumping vitamin D3 over the side in urine...  That can and does happen... but it usually occurs at 25(OH)D concentrations well above 60 to 80 ng/mL. 

In that case, calcium homeostasis kicks in and the parathyroids slow the production of PTH.  This signals the kidneys to slow the metabolism of 25(OH)D to 1,25(OH)2D, the active hormonal vitamin D3 metabolite that pulls calcium from the gut and pushes it into the bloodstream...   

Instead, the kidneys metabolize 25(OH)D into 24,25(OH)2D and 1,24,25(OH)3D, both of which are inactive with respect to calcium.  These two vitamin D3 metabolites are then eliminated in the urine...  This serves as an important feedback mechanism to avoid vitamin D toxicity.

If serum concentrations of 25(OH)D and total calcium are low... the body metabolizes large doses of vitamin D3 up to 100,000 IU and higher very effectively...

Hope this helps.

Take care,

V/R, Batch
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« Last Edit: Dec 19th, 2012 at 4:48am by Batch »  

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Re: Vitamin D3 and anxiety
Reply #9 - Dec 19th, 2012 at 8:57am
 
never noticed anxiety...  my wife takes more than i do and she actually has less anxiety than before.

now, i have noticed that i dont get tired late at and end up studying or reading all night, sometimes.

  that could just be me feeling good though.
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Re: Vitamin D3 and anxiety
Reply #10 - Jan 8th, 2013 at 10:38am
 
I was one of the folks that took 50,000iu daily for 2 weeks and then dropped to 10,000iu daily with a 50,000iu weekly loading dose which is equivalent to 15,000iu daily which i take now without a weekly loading dose. I got my 25ohd lab test 6 days after i reduced my intake from 50,000iu daily to the 10,000iu daily and loading dose. My level was a 62 ng/ml and never felt better in my life just wonderful energy. I was chronic for 37 years and the last 6 months was incredibly bad with at least 10 CH's daily and 80% were kip 10's. After starting this regimen i went pain free in 3 days and now have been pf for 80 days and my last 25 ohd test was a 83 ng/ml. I am scheduled for another 25 ohd test in a week to make sure i'm leveled out.
All i can say is my doctor after trying to treat and stop my CH with many other meds was stunned! This regimen has worked for me and life being CH free is AWESOME!!......Johnny Wink
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« Last Edit: Jan 8th, 2013 at 10:59am by Clusterman59 »  

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