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Rotigotine in CCH. (Read 1884 times)
Hoppy
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Rotigotine in CCH.
May 28th, 2013 at 9:32pm
 







Cephalagia  24/may/2013.

A case in cluster headache treated with Rotigotine: clinical and
neurophysiological correlates.

Source, Don Carlo Gnocchi Onlus Foundation, Italy.

Abstract.

Background. Chronic cluster headache (CCH) is characterized
by recurrent bouts of facial pain lasting up to 180 minutes
in the absence of a long remission period.

Case: We report the case of a 43-year old male patient with
treatment-resistant CCH, who improved with administration of
transdermal Rotigotine. We also evaluated the nociceptive
blink reflex habituation that was reduced before the treatment
(as is usual in CH patients) and normalized by transdermal
Rotigotine.                                                                              

Conclusions. We suggest that Rotigotine could represent a
further therapeutic option in the treatment of drug-resistant CCH.
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« Last Edit: May 28th, 2013 at 9:40pm by Hoppy »  
 
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Hoppy
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LAUGHTER IS THE BEST MEDICINE


Posts: 1890
Perth WA
Gender: male
Re: Rotigotine in CCH.
Reply #1 - May 28th, 2013 at 9:56pm
 
PS. Rotigotine is more known for the treatment in Parkinson"s
disease.
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nani
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Los Lunas NM USA
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Re: Rotigotine in CCH.
Reply #2 - May 28th, 2013 at 10:14pm
 
Interesting. A study of one doesn't lead me to believe this may be some new breakthrough, especially given it is a dopamine agonist, and I can't recall seeing anything like it applied to CH treatment before. It seemed to help the patient's twitchy eye, too.
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Mike NZ
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Re: Rotigotine in CCH.
Reply #3 - May 28th, 2013 at 11:48pm
 
Interesting, however a study of one person where they "improved" does little other than suggest that further work is very much needed.
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Hoppy
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LAUGHTER IS THE BEST MEDICINE


Posts: 1890
Perth WA
Gender: male
Re: Rotigotine in CCH.
Reply #4 - May 28th, 2013 at 11:57pm
 
Hi Nani,
I think the blinking eye they are referring to, is  the drooping eye we get when suffering a CH attack
Hoppy.
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nani
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Los Lunas NM USA
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Re: Rotigotine in CCH.
Reply #5 - May 29th, 2013 at 12:26am
 
I get a twitchy eye when in cycle and the droopy eye during an attack. The twitching drives me nuts, but it only happens between attacks and isn't painful on its own.
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Here I sit between my brother the mountain and my sister the sea. We three are one in loneliness, and the love that binds us together is deep and strong and strange.~Kahlil Gibran
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Hoppy
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LAUGHTER IS THE BEST MEDICINE


Posts: 1890
Perth WA
Gender: male
Re: Rotigotine in CCH.
Reply #6 - May 29th, 2013 at 2:59am
 
Hi Nani,
I've never read anything on twitchy eyes in CH sufferes. I myself
hav'nt experienced them , is it common in CH, or just in CCH.?
I'm thinking because that patient was drug resistent to all other
treatments, is why they tried Rotigotine after doing  research.
Hoppy.
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AussieBrian
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Cairns, Qld, Australia
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Re: Rotigotine in CCH.
Reply #7 - May 29th, 2013 at 4:01am
 
Good find, Hoppy, because every avenue must be explored. Even blind alleys have secrets of delight.
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My name is Brian. I'm a ClusterHead and I'm here to help. Email me anytime at briandinkum@yahoo.com
 
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Callico
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Aurora IL
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Re: Rotigotine in CCH.
Reply #8 - May 30th, 2013 at 1:21am
 
Interesting possibility, but I think I'm with Nani on this one.  I get the twitching eye also, and occasionally a twitchy hand and leg, which my Neuro was concerned was Parkinson's.  Fortunately, I do't' fit the other parameters of the disease, but we will be keeping an eye on it as my mother has Parkinson's.
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"Political correctness is a doctrine, fostered by a delusional, illogical minority, and rabidly promoted by an unscrupulous mainstream media, which holds forth the proposition that it is entirely possible to pick up a piece of dung by the clean end." Texas A&M Student (unknown)
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Hoppy
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LAUGHTER IS THE BEST MEDICINE


Posts: 1890
Perth WA
Gender: male
Re: Rotigotine in CCH.
Reply #9 - May 30th, 2013 at 3:40am
 
Hi Jerry,
Thanks for your answer to my question on twitchy eyes.            
I remember my mum alway's saying, old age does'nt
come by itself, maybe this can also apply to us suffering
from CH. Sorry to hear about your mum, does she use a
Rotigotine patch.?

Hoppy.
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