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Just a theory (Read 1671 times)

stillgone

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Just a theory
Sep 10^th, 2013 at 11:49am

Vasodilation causes your veins to expand at least as I understand it. For example; if you have a kink clog in a water hose it expands, much like a vein would I suspect. If you constrict the water flow for a hose / lessen blood flow through your veins like a Vasoconstrictor does for blood. Example; pure oxygen for blood; less water for a hose , less expansion. I believe if you get rid of the kink / clog; call it what you will, you'll have no expansion of the vein against the nerve endings. Just a theory.

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Marc

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Re: Just a theory
Reply #1 - Sep 11^th, 2013 at 8:13pm

Precisely why my doctor wanted to see an MRI and an MRA - to rule out the deadly stuff first. It seems that there are some deadly malady's that can mimic SOME Cluster Headache symptoms. The first thing that he wanted to look for were aneurisms - the "bulges" you describe in your water hose analogy.

However, there are many of us who feel that CH's are not simple vascular headaches caused by expanding blood vessels like Migraines are. That theory came strictly from "our" response to Migraine medications. More current thinking (by the researchers specializing in this) includes the idea that CH's are actually Neurological in nature and are far more complex - hence the radically difference pain response when compared to Migraines.

There has been enough research evidence supporting this to trigger radically different approaches to treatment of CH's.

So..... why do Migraine meds like Triptans work for us? No one knows for sure, but the studies always seem to eventually loop back to Hypothalamus interaction with nerves.

If you suffer from these monsters, I don't have to explain the reason that you should spend every available minute (and some that aren't!) reading the information on this site.

Marc

« Last Edit: Sep 11^th, 2013 at 8:33pm by Marc »

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Callico CH.com Hall of Famer Offline Author of "Stranded at Romson's Lodge Posts: 4916 Aurora IL Gender:	Re: Just a theory Reply #2 - Sep 13^th, 2013 at 11:28pm Dr Goadsby said a month or so ago the CH has been determined to be a Central Nervous System event, not vascular. It seems to start in the Hypothalamus, and remains a CNS event. Dr McGeeny talking about Trex today at the CB conference said Trex has effect on the hypothalamus as well as on the vascular effect. Jerry
Back to top	"Political correctness is a doctrine, fostered by a delusional, illogical minority, and rabidly promoted by an unscrupulous mainstream media, which holds forth the proposition that it is entirely possible to pick up a piece of dung by the clean end." Texas A&M Student (unknown) IP Logged

Marc CH.com Old Timer Offline Posts: 429 TX Gender:	Re: Just a theory Reply #3 - Sep 15^th, 2013 at 3:55pm Jerry, I remember several members here taking big time flack for suggesting that was the case, not so long ago! Once the hypothalamus was shown to "activate" on PET scans during a hit, it made sense to me. Marc
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Mike NZ CH.com Hall of Famer Offline Oxygen rocks! D3 too! Posts: 3785 Auckland, New Zealand Gender:	Re: Just a theory Reply #4 - Sep 16^th, 2013 at 2:09am Whilst it has been shown that the hypathalamus is activated during a PET scan whilst a CH kicks off, it still doesn't prove that it is where it originates (from what I've read).
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wimsey1 CH.com Alumnus Offline I Love CH.com! Posts: 2457 MA Gender:	Re: Just a theory Reply #5 - Sep 16^th, 2013 at 9:02am Mike NZ wrote on Sep 16^th, 2013 at 2:09am: Whilst it has been shown that the hypathalamus is activated during a PET scan whilst a CH kicks off, it still doesn't prove that it is where it originates (from what I've read). It originates in Hell. How it finds my hypothalamus I have no idea. Blessings. lance
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Guiseppi

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Re: Just a theory
Reply #6 - Sep 16^th, 2013 at 11:01am

wimsey1 wrote on Sep 16^th, 2013 at 9:02am:

Mike NZ wrote on Sep 16^th, 2013 at 2:09am:

Whilst it has been shown that the hypathalamus is activated during a PET scan whilst a CH kicks off, it still doesn't prove that it is where it originates (from what I've read).

It originates in Hell. How it finds my hypothalamus I have no idea. Blessings. lance

Hmm.....finally a theory I can wrap my arms around! Grin

Joe

"Somebody had to say it" is usually a piss poor excuse to be mean.

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Racer1_NC CH.com Moderator CH.com Alumnus Offline "Well, let's go see." Posts: 4417 Lewisville, NC Gender:	Re: Just a theory Reply #7 - Sep 16^th, 2013 at 1:01pm wimsey1 wrote on Sep 16^th, 2013 at 9:02am: It originates in Hell. How it finds my hypothalamus I have no idea. This.....
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Mike NZ

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Re: Just a theory
Reply #8 - Sep 17^th, 2013 at 4:50am

wimsey1 wrote on Sep 16^th, 2013 at 9:02am:

Mike NZ wrote on Sep 16^th, 2013 at 2:09am:

Whilst it has been shown that the hypathalamus is activated during a PET scan whilst a CH kicks off, it still doesn't prove that it is where it originates (from what I've read).

It originates in Hell. How it finds my hypothalamus I have no idea. Blessings. lance

Best explanation I've heard for quite a while.

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