Hi Everyone,
When I discovered this site (CH.com), it was with relieved amazement that I discovered that I'm not alone. The reason for this, was that within my friends, family and colleagues realm, CHs were unknown and consistently being compared/confused with migraines. After batteries of tests, I was diagnosed by an optometrist with CH.
I have been suffering from CH for the last 8 years and as I think everyone do, there is this constant search for something that will ease and hopefully break a CH.
I get my CHs in April/May and in the last 3 years November also invited itself. So last year when I was in my "spell", a colleague asked if I wanted some capsules she got from her GP. Although understandingly super skeptic, I did proclaim that nothing helps, but took the 2 capsules in any case.
At the time, I was already about 10 minutes into my spell, when I took the Synaleve capsules. To my surprise, within about 5 - 7 minutes, I detected the slightest trace of a release. Still in the very skeptic mode, I was amazed that after 10 - 12 minutes, the CH was beginning to break and 20 minutes after taking the capsules, my CH was history.
First conclusion I made, this was coincidence and maybe I was just fortunate that I had a mild spell. But grasping at any or all straws, I was at my GP for a prescription for Synaleve Capsules. In South Africa this is a Schedule 5 (S5) prescription drug and can't just be purchased over the counter.
Armed with my Synaleve Capsules that night, still very skeptic, I was hoping this will be a wonder intervention. Even if it only helps occasionally. Well, I went to sleep and as clockwork, an hour and a half later, I woke up with the CH in full swing. Being prepared for this, the capsules were on my bedside table and I took 2 of them.
10 minutes later, those first milliseconds of pain release and another 5 minutes, the CH was gone!

Subsequently, I found that if I drink the Synaleve capsules, at the hint of the CH approaching, it would actually prevent the CH or reduce it to like 5 minutes.
Well, last year with my November period, I ended up having 4 full blown CHs in the 4 week period! Whoohoo!
Being very excited, but also still very skeptic about this, I thought let me just put this to the proof with my period in April/May. In my 6 week period now, which is coming to it's end, I have had only 2 semi CHs and 2 full blown ones. To me, that is a 1000% improvement!
I'm not sure whether Synaleve capsules have been mentioned on this site before, but my only aim is to inform everyone of this personal discovery, in the hope that it could also help someone else.
Another interesting finding I made, is that the Synaleve doesn't seem to work as aggressive "outside" my CH periods. Something like ADCO DOL then seems to work better.
I preparing to place this post, I thought I would do some research on the NET, to provide a bit more factual information on the post. To my surprise, there is very little information available. I have found this site that contains some information: [Not allowed to paste the URL]
I copied the content of the site below: Synaleve Capsules
Synaleve Capsules consists of Acetaminophen, Codeine Phosphate, Meprobamate.
Acetaminophen - Acetaminophen, also known as paracetamol, is commonly used for its analgesic and antipyretic effects. Its therapeutic effects are similar to salicylates, but it lacks anti-inflammatory, antiplatelet, and gastric ulcerative effects.
Indication: For temporary relief of fever and minor aches and pains.
Synaleve Capsules (Acetaminophen) (USAN) or Paracetamol (INN) is a widely used analgesic and antipyretic drug that is used for the relief of fever, headaches, and other minor aches and pains. It is a major ingredient in numerous cold and flu medications and many prescription analgesics. It is extremely safe in standard doses, but because of its wide availability, deliberate or accidental overdoses are not uncommon. Acetaminophen, unlike other common analgesics such as aspirin and ibuprofen, has no anti-inflammatory properties or effects on platelet function, and it is not a member of the class of drugs known as non-steroidal anti-inflammatory drugs or NSAIDs. At therapeutic doses Synaleve Capsules (Acetaminophen) does not irritate the lining of the stomach nor affect blood coagulation, kidney function, or the fetal ductus arteriosus (as NSAIDs can). Like NSAIDs and unlike opioid analgesics, Synaleve Capsules (Acetaminophen) does not cause euphoria or alter mood in any way. Synaleve Capsules (Acetaminophen) and NSAIDs have the benefit of being completely free of problems with addiction, dependence, tolerance and withdrawal. Synaleve Capsules (Acetaminophen) is used on its own or in combination with pseudoephedrine, dextromethorphan, chlorpheniramine, diphenhydramine, doxylamine, codeine, hydrocodone, or oxycodone.
Codeine Phosphate - This medication is used to treat mild to moderately severe pain. Codeine phosphate is a narcotic pain reliever. It acts on certain centers in the brain to give you pain relief.
Meprobamate - A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Synaleve Capsules (Meprobamate) has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of anxiety disorders, and also for the short-term management of insomnia but has largely been superseded by the benzodiazepines. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603) Synaleve Capsules (Meprobamate) is a controlled substance in the U.S.
Indication: For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety.
Synaleve Capsules (Meprobamate) is an anxiolytic drug. It was the best selling minor tranquilizer for a time but has largely been replaced by benzodiazepines. Synaleve Capsules (Meprobamate) has most of the pharmacological effects and dangers of the barbiturates (though it was marketed as being safer). However, it is less sedating at effective doses. It is reported to have some anticonvulsant properties against absence seizures, but can exacerbate generalized tonic-clonic seizures. It has also been used as a hypnotic (sleeping pill). However, it is currently only licensed as an anxiolytic and it is a third or fourth-order choice.
Pharmaceutical active ingredients containing related brand and generic drugs, medications or other health care products:
•Acetaminophen
•Codeine Phosphate
•Meprobamate
Synaleve Capsules available forms, composition, doses:
•Capsules; Oral; Acetaminophen; Codeine Phosphate; Meprobamate
Synaleve Capsules destination | category:
•Human
Indications and usages, anatomical therapeutic chemical and diseases classification codes:
•N/A
Pharmaceutical companies, researchers, developers, manufacturers, distributors and suppliers:
•Adcock Ingram
I really hope this information will be helpful to anyone. May your fortune also turn around like mine did!!