Traveller,
Fair question... We've discussed this in several posts in the past... that said, covering it again won't hurt.
If you listened to the nanny state, big government bureaucrats (none are physicians) on the Nutrition Board at the Institute of Medicine, (IOM)... you'd be taking 400 IU/day vitamin D3... and the CH beast would still be hammering away on the back of your eye...
Unfortunately there are too many physicians who never studied the use of nutrients like vitamin D3 in treating anything but rickets, osteomalacia or osteoporosis... They also likely listened to the IOM for the recommended daily dose of vitamin D3.
The simple fact is the human body needs vitamin D3 so much it makes its own in the skin when exposed to the UVB in sunlight. Our bodies can generate 15,000 IU of vitamin D3 in as little as 10 to 15 minutes exposure to the UVB in mid day sunlight... clad in a bathing suit without any sun block...
Neurologists have been treating RRMS patients with vitamin D3 for years... The doses range from 10,000 to 40,000 IU/day. The following link tells the story...
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Can you take too much vitamin D3? You bet! You can also die from drinking too much water...
In reality, it's not the dose of vitamin D3 that's critical, but rather the dose, duration and resulting 25(OH)D serum concentration that's important. A sustained serum concentration of 25(OH)D at 80 ng/mL is very safe and a good therapeutic level to prevent CH... and a lot of other preventable medical conditions.
Unless there's another medical condition like hyperparathyroidism or sarcoidosis, there are several studies that concluded otherwise healthy people can likely take sustained doses of vitamin D3 up to 40,000 IU/day without fear of vitamin D3 intoxication... Of course, taking this much vitamin D3 on a sustained basis should be done with medical supervision.
Bottom line... a sustained dose of 10,000 IU/day vitamin D3 is very safe. Moreover, the FDA's list of medications and vitamins with adverse reactions indicates there have been no, (zero), deaths attributed to taking vitamin D3 in the history of this database... You can't say that for verapamil, depakote, and nearly all the rest of the medications prescribed to prevent CH.
Take care,
V/R, Batch