Hey Tara,
Welcome to CH.com. You've come to the right place. We know what you're going through with CH and the good news is it doesn't need to be that way...
You've got a double whammy with CH and MS... The interesting news is both medical conditions are associated with a low 25(OH)D serum concentration (vitamin D3 deficiency), and the good news is both conditions respond very well to the anti-inflammatory regimen with at least 10,000 IU/day vitamin D3.
Ask your PCP or neurologist for the 25(OH)D lab test. The odds are you are vitamin D3 deficient, i.e., a 25(OH)D serum concentration less than 30 ng/mL.
The normal reference range for the 25(OH)D lab test is 30 to 100 ng/mL and most CH'ers respond to the anti-inflammatory regimen with a cessation of their CH when they elevate their 25(OH)D serum concentration up around 80 ng/mL.
RRMS takes a bit higher 25(OH)D serum concentration between 80 and 130 ng/mL. They conducted a very important study of RRMS patients taking escalating doses of vitamin D3 in six week increments up to 40,000 IU/day over a one year period. All participants responded to this dosing schedule and there were no adverse events.
You can read the final report of this study at the following link:
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I have two very dear friends with RRMS. Both responded to the anti-inflammatory regimen and are no longer taking any of the more invasive medications usually prescribed for RRMS... They're both now leading very normal lives.
The "Go To" link with info on all the anti-inflammatory regimen supplements, doses, drug interactions and contraindications follows:
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The following table represents the latest list of anti-inflammatory regimen supplements and doses:
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I've found the following supplements shown by brand in the photo below are formulated with most of the supplements we need. I buy them at Costco, but you should be able to find similar formulations at most Vitamin Shoppes, supermarkets, Wall-Mart or over the Internet at Amazon or iHerb:
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The vitamin B 50 is not shown. You’ll need a 3-month course of vitamin B 50 to handle any deficiencies among the seven B vitamins. Although the Super K with vitamin K2 complex isn't essential in preventing CH, it is needed to handle the increased serum calcium made available by taking vitamin D3 at the doses we take.
There are a growing number of studies finding the super K2 complex helps direct calcium away from soft tissues and arteries directing it instead to bones and teeth improving overall bone mineral density.
There are also a number of studies that have addressed the optimum ratio of calcium-magnesium supplements. The general consensus is to keep these two supplements at a 1:1 ratio. Many have found 400 mg/day sufficient.
Most CH'ers who have started this regimen in the last year and had their 25(OH)D results come back below 30 ng/mL, have used the accelerated vitamin D3 dosing schedule and found it got them pain free faster than taking the maintenance dose of vitamin D3 at 10,000 IU/day... The accelerated vitamin D3 dosing schedule follows:
On day one, take the entire regimen with 10,000 IU/day vitamin D3 and two of the Omega-3 Fish Oil liquid softgel capsules along with one each of the remaining supplements the first day.
If there's no allergic reaction to these supplements (very rare), take 20,000 IU/day vitamin D3 for the next two weeks along with the rest of the regimen.
In addition, for the first two weeks take a 50,000 IU loading dose (ten of the 5,000 IU vitamin D3 softgels) once a week on top of the daily dose for two weeks. The day of the loading dose you'll be taking a total of 70,000 IU vitamin D3.
After two weeks on the above vitamin D3 dosing schedule, stop taking the once a week loading dose and lower your daily vitamin D3 intake to 15,000 IU/day. Continue at this dose for another two weeks then lower the vitamin D3 intake to a maintenance dose of 10,000 IU/day. At that point see your PCP for another lab test for 25(OH)D.
If you total the vitamin D3 doses you'll be taking 600,000 IU vitamin D3 over the 4 week period. This should elevate your 25(OH)D serum concentration by 60 ng/mL, (150 nmol/L) above your starting level. Assuming that starting level was less than 30 ng/mL, (75 nmol/L), your serum concentration should be around 85 ng/mL, (212 nmol/L).
If you're like most of the other CH'ers who start this regimen, you'll experience a favorable response within the first week to ten days. Migraineurs sail through their usual cycle times with nary a twinge...
If you have questions please contact me at pete.batcheller@verizon.net or Skype me. My Skype Name is pete_batcheller.
Again, the above regimen of over the counter nutrients (vitamins and minerals) is called the anti-inflammatory regimen. You can read all about it along with more about the relationship between vitamin D3 and MS at the following links:
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Take care, please feel free to ask questions... and do keep us posted on your results after starting this regimen.
V/R, Batch.