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Chasing cheap abortives? (Read 888 times)
Bob Johnson
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Kennett Square, PA (USA)
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Chasing cheap abortives?
May 9th, 2016 at 1:33pm
 
For many years I've been posting this abstract. It's been surprising that not six folks have reported giving it a try--even as it's as effective and cost, per dose, much less.

Once I discovered it, I used no other abortive until I finally aged out of having Clusters.

Your doc can give you a free sample and one or two doses will show whether it works for you.
===================================
Headache 2001 Sep;41(8):813-6 

Olanzapine as an Abortive Agent for Cluster Headache.


Rozen TD.
Department of Neurology, Jefferson Headache Center/Thomas Jefferson University Hospital, Philadelphia, Pa.

OBJECTIVE: To evaluate olanzapine as a cluster headache abortive agent in an open-label trial. BACKGROUND: Cluster headache is the most painful headache syndrome known. There are very few recognized abortive therapies for cluster headache and fewer for patients who have contraindications to vasoconstrictive drugs. METHODS: Olanzapine was given as an abortive agent to five patients with cluster headache in an open-label trial. THE INITIAL OLANZAPINE DOSE WAS 5 MG, AND THE DOSE WAS INCREASED TO 10 MG IF THERE WAS NO PAIN RELIEF. THE DOSAGE WAS DECREASED TO 2.5 MG IF THE 5-MG DOSE WAS EFFECTIVE BUT CAUSED ADVERSE EFFECTS. To be included in the study, each patient had to treat at least two attacks with either an effective dose or the highest tolerated dose. RESULTS: Five patients completed the investigation (four men, one woman; four with chronic cluster, one with episodic cluster). Olanzapine reduced cluster pain by at least 80% in four of five patients, and TWO PATIENTS BECAME HEADACHE-FREE AFTER TAKING THE DRUG. Olanzapine typically alleviated pain within 20 minutes after oral dosing and treatment response was consistent across multiple treated attacks. The only adverse event was sleepiness. CONCLUSIONS: Olanzapine appears to be a good abortive agent for cluster headache. IT ALLEVIATES PAIN QUICKLY AND HAS A CONSISTENT RESPONSE ACROSS MULTIPLE TREATED ATTACKS. IT APPEARS TO WORK IN BOTH EPISODIC AND CHRONIC CLUSTER HEADACHE.

PMID 11576207 PubMed

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Olanzapine has a brand name of "Zyprexa" and is a antipsychotic. Don't be put off by this primary usage. Several of the drugs used to treat CH are cross over applications, that is, drugs approved by the FDA for one purpose which are found to be effective with unrelated conditions--BJ.
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« Last Edit: May 16th, 2016 at 6:53am by Bob Johnson »  

Bob Johnson
 
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purpleydog
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Re: Chasing cheap abortives?
Reply #1 - May 12th, 2016 at 7:54pm
 
Hello Bob,

I've tried this before, and it does work for me. It was under the brand name of Zyprexa, it was posted on the board here years ago. I told my neuro, he prescribed it to me, and it works fast. 10 mg tablets cut in half, side effect was tiredness, but it's as good as imitrex or O2 as an abortive. I'd get a script for 5 tablets with a refill.

In this day and age of privacy issues, including your medical information, I can tell you there is a possibility that a doc may see that you've taken it, and not concern themselves with why you took it.

But it does work. I had no long term side effects, and it did give me a break (I was chronic at the time).
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