Hey Pictou,

Good move starting the anti-inflammatory regimen with 10,000 IU/day vitamin D3. You won't be sorry...

The total loading dose is 600,000 IU of vitamin D3.  This is sufficient for most adult CHers to elevate their 25(OH)D from 25 ng/mL to 85 ng/mL.  This total loading dose can be taken orally in one day, one week, or as I suggest, the 2-week or 4-week loading schedules.

I'd switch to the 2-week vitamin D3 loading schedule as it works much faster in elevating your serum 25(OH)D up to the therapeutic level of 80 ng/mL.  Better yet take 50,000 IU/day vitamin D3 for 12 days then drop back to the 10,000 IU/day maintenance dose.

At the two month mark after starting this regimen, try to see your PCP for the 25(OH)D lab test.  If your serum 25(OH)D concentration comes back at 80 ± 10 ng/mL. stay at that dose.  If it comes back >100 ng/mL, skip the 10,000 IU/day maintenance dose on Sundays...

Most CHers respond to the 2-week vitamin D3 loading dose in less than a week, some in less than 24 hours.

Take care and please keep us posted.

V/R, Batch