Hey Colin,

Thanks for the update...  I wouldn't worry about your 25(OH)D serum concentration at 288 nmol/L (115.2 ng/mL).  It's no biggie, particularly if it's keeping you CH pain free...  My average 25(OH)D serum concentration over the last three years is 140 ±50 ng/mL (350 ± 125 nmol/L).

My PCP just looks at my labs and smiles... then says..."Your serum 25(OH)D is elevated... as usual... However as your serum calcium is normal and your PTH is low... I guess you know what you're doing controlling your CH this way...  (He has a copy of the treatment protocol).

If you still feel uncomfortable with your 25(OH)D this high, drop the vitamin D3 dose to 10,000 IU/day.  Your serum 25(OH)D will start dropping slowly.  If you're episodic, you can let it drop to 200 nmol/L. If you're a chronic CHer, I wouldn't let it drop below 250 nmol/L. 

The survey data indicates chronic CHers who experienced a favorable or pain free response to this regimen are maintaining a mean 25(OH)D serum concentration of 100 ng/mL (250 nmol/L).

As you're still not 100% CH pain free, you might want to try the Children's Benadryl (Diphenhydramine HCL) liquid allergy medicine

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12.5 mg (5 mL in the measuring cap) when you get home for the day and done driving and 25 mg before bed.

Take care and please keep us posted.

V/R, Batch