what about seasonality ?

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Posted by gary g ( on November 03, 1999 at 12:51:03:

In Reply to: For your consideration, once more LONG POST posted by Michel L on November 02, 1999 at 22:35:48:

trying to keep my questions separate and discrete, because this is exactly the way we need to work on this challenge

start with a VERY well thought out model like Michel presents, and then look for parts of it that aren't consistent with standard experience

then those details need to be either satisfactorily adjusted, in which case the hypothesis "as revised" continues thru scrutiny OR a part of it is absoltuely indefensable, but inseperable from the hypothesis, and then we need move on

SO - Michel
THANKS for putting the board on a responsible, intelligent, constructive path -for once (:->)

My second observation:

The daily rhythym may well be explained by your neural transmission variance - interuppted by low oxygenation, etc

BUT - what do we do with the (large majority) seasonal aspect ? believing as Donna pointed out, that most structural myleitis (sp?) situations are irreversable - I can't see what would cause the very pronounced seasonal cycling of vulnerability in a theoretically damaged sheathing region

bear in mind this seasonality appears to be age, location and disease tenure independent

theories anyone ?

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