National Institute of Health Study

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Posted by Jamy ( on January 23, 2000 at 16:51:10:

This is a copy and paste of the info from the NIH studies department:
For the life of me I don't know how some of you cut and paste the way you do.

Title: Somatosensory Studies of Pain and Pain Control Measured with Oxygen-15 Water Positron Emission Tomography and Functional MRI in Normals and Patients with Neuropathic or Chronic Pain Conditions

Number: 92-D-0243

Summary: Regional cerebral blood flow (rCBF) will be measured while normal subjects, patients with post-operative pain, and patients with neuropathic abnormalities of pain sensation are exposed to a battery of somatosensory stimuli that activate
known pathways subserving touch, temperature and pain sensations. Patients with peripheral neuropathies and other chronic pain conditions that cause spontaneous pain, hyperalgesia, and allodynia (pain sensation to a normally non-noxious stimulus) will be examined with and without applied experimental stimuli. Data from the patient groups will be compared to those of normal controls. In addition, an ultrashort opioid analgesic will be administered to normally and select patients in order to map opioid modifications of pain neural activity. Activation of several somatosensory modality in conjunction with high resolution positron emission tomography (PET), adjunctive structural imaging with magnetic resonance imaging (MR.) and analgesic drug manipulations will functionally, anatomically, and pharmacologically characterize the physiology and pathophysiology of nociceptive in human beings.

Sponsoring Institute:
National Institute of Dental And Craniofacial Research (NIDCR)

Recruitment Detail
Type: Active Accrual Of New Subjects
Gender: Male & Female

Referral Letter Required: No

Population Exclusion(s): None

Eligibility Criteria:
Inclusion Criteria: Healthy Normal Volunteers between the ages of 18 and 80 years.
Certain Chronic Pain Patients.
Exclusion Criteria: Structural or Functional Brain Defects.
Metallic Surgical Implants.
Chronic Drug Treatments.

Special Instructions: Currently Not Provided

Disease Category: Symptoms, Signs, & Ill Defined Conditions

Positron Emission
Functional Brain Imaging
Somatosensory Cortex
Reflex Sympathetic Dystrophy

Recruitment Keywords: Normal Volunteer
Chronic Pain

Investigational Drug(s): Oxygen-15 Water

Investigational Device(s): None

Patient Recruitment and Public Liaison Office, CC.
Building 61
10 Cloister Court
Bethesda, Maryland 20892-4754
Long Distance Calls: 1-800-411-1222
Fax: (301) 480-9793

I know this is pasted yucky but I hope that knowing that NIH does clinical trials, could be a help.

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