Posted by Todd (18.104.22.168) on February 13, 2000 at 07:39:38:
In Reply to: Quasy answer posted by Miguel on February 13, 2000 at 00:29:42:
Thanks, Miquel, but that wasn't what I was asking. I'm fully aware of the differences in absorption rates and doses.
My point was that the drug itself (sumatriptan) is exactly the same in all three forms, and therefore must have exactly the same effect, once a sufficient amount reaches the appropriate spot.
Due to the rate of dissolution of the tablet form, the patient must learn to 'read' their cluster signals and pop the pill at the right time. If this is done properly, aborting the attack in 15 minutes is very reliable.
Few injection users claim a response rate faster than this. The advantage to using the injections is that they allow the user to wait longer before dosing, NOT that the injections work and the tabs don't.
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