Posted by Flash (22.214.171.124) on February 24, 2000 at 05:53:32:
In Reply to: A question for FLASH. posted by Luke on February 23, 2000 at 22:42:15:
I've corresponded with seven people on this subject (including yourself):
4 incl myself found this treatment worked 100%.
3 could only verify that they had skipped episodes years before and that this corresponded to recreational use of LSD etc.
2 incl yourself for who it had no apparent impact or possibly detrimental.
What we think the psilocilin does is mimic serotonin. What we don't know is whether an excess or a lack or serotonin is a factor in CH. There are also several types or serotonin receptor in the brain. We don't know which ones are affected by psilocilin. It could be that some of us are lucky in that the psilocilin is a good fit for our particular chemical imbalance.
What all of this does show is that whether psilocilin agrivates or placates CH, as long as it has an effect it is worth investigating.
We really need a clinical study on a large number of CH sufferers with all drugs that contain indole ring structures. Until then we are all jumping to conclusions.
If you are a recreational user, then you might be able to help by administering this class of substance to yourself during an episode and noting the results. That of course takes a lot of bottle.
Another thing I'd bve interested to know is what species of mushroom, how often you take it, and have you ever used LSD?
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