LSD blood-brain absorbtion


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Posted by Q (198.64.206.92) on July 26, 2000 at 01:59:30:

In Reply to: I doubt that it crosses the blood-brain barrier posted by Ted on July 26, 2000 at 00:24:34:

In article manderso@uxa.cso.uiuc.edu (anderson mark david) writes:

Speaking of LSD, here is some interesting information from the new 3rd
edition of the Psychedelics Encyclopedia, by Peter Stafford, which I
happened to spot on the new book shelf here at UCR's library.

"LSD is a very curious chemical. When given by injection, it disappears
rapidly from the blood. It can be observed when tagged with carbon 14
in all the tissues, particularly the liver, spleen, kidneys and adrenal
glands. The concentration found in the brain is lower than in any other
organ - being only about 0.01 percent of the administered dose. Sidney
Cohen, in The Beyond Within, has estimated that an average dose results
in only some 3,700,000 molecules of LSD (about 2/100ths of a microgram
crossing the blood-brain barrier..." (Does this sound reasonable?)



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