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Posted by dougW ( on July 27, 2000 at 11:45:51:

In Reply to: seizure during a cluster posted by lee on July 26, 2000 at 23:54:38:

Lee: As others have said, I'm not aware of seizures with clusters. A recent article from medscape is below, as reported by reuters News from the Journal Neurology , about seizures and migraines (Migralespy). While this may not apply to your husband, it may give your Docs a place to start looking.

Good luck. Doug

Case of 'Migralepsy' Suggests Link Between Epilepsy, Migraine

WESTPORT, Jul 19 (Reuters Health) - The case of a 51-year-old woman who
experienced a seizure during a migraine attack without aura highlights "the complex
relationship between migraine and epilepsy," researchers comment in the June issue of

Drs. Scott Friedenberg and David W. Dodick of the Mayo Clinic, Scottsdale, Arizona,
note that the woman "presented with left homonymous hemianopia, confusion, and a
generalized tonic-clonic seizure during one of her stereotypical migraines without aura."

The patient had no history of migraine with aura, complicated migraine or seizures.
Gadolinium-enhanced magnetic resonance imaging showed marked enhancement of the
right parieto-occipital region. However, MRI and other testing at 9 days after the headache
began indicated "near complete resolution of the abnormally enhancing regions."

The patient was discharged after 12 days. Her headache and sensory neglect had resolved,
although her visual field deficit continued. She initially had difficulty with dressing and
navigating around the house, and with short-term memory.

These symptoms resolved by week 5, and at 6 months' follow-up, MRI and neurological
examination demonstrated a return to baseline. The patient's biweekly migraines without
aura returned and she continued on prophylactic treatment with valproic acid and aspirin.

This case of "migralepsy," the researchers conclude, "supports the intimate association
between migraine and seizures, lending weight to the concept of a shared
pathophysiological mechanism, not only between these two disorders but also between
migraine and migraine without aura."

Headache 2000;40:487-490.

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