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Posted by Miguel ( on August 16, 2000 at 01:00:46:

In Reply to: actifed posted by Barbara on August 15, 2000 at 22:10:21:

Actifed is an anti-histaminic agent like no other.

Pseudoephedrine (actifed contains this)

Classification: Direct- and indirect-acting
sympathomimetic (the difference), nasal decongestant

Action/Kinetics: Produces direct stimulation of
both alpha-(pronounced) and beta-adrenergic
receptors, as well as indirect stimulation
through release of norepinephrine from storage
. Results in decongestant effect on the
nasal mucosa. Systemic administration
eliminates possible damage to the nasal mucosa.

Onset: 15-30 min. Time to peak effect: 30-60 min.
Duration: 3-4 hr. Extended-release: duration, 8-12 hr.
Urinary excretion slowed by alkalinization,
causing reabsorption of drug.

Uses: Nasal congestion associated with sinus
conditions, otitis, allergies. Relief of
eustachian tube congestion.


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