Posted by Miguel (126.96.36.199) on September 11, 2000 at 21:10:32:
In Reply to: Similarities explained in detail posted by pinksharkmark on September 11, 2000 at 09:59:56:
Well, but the LSD molecule is quite different,
yet apprarently as effective as psy. I wonder
if the activity, or lack thereof, comes from the
lower part of the molecule, the indole ring.
It seems that the LSD molecule would have a heck
of time binding to the "upper" part of the 5-HT2A
receptor, tus perhaps its partial agonist/antagonist status.
I wonder what happen fi the hydroxy group was bumped
on carbon further down on the benzene ring...
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