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Posted by Miguel ( on January 20, 2001 at 11:09:07:

In Reply to: This is interesting... posted by Bennie Sue on January 19, 2001 at 19:28:32:

"The test (as best I recall) was like this:
About a dozen patients were tested. A CH
attack was induced via nitroglycerin, ..."

See, I think that the test that these people conducted,
and in view of the new knowledge, would produce somewhat
flawed results. The reason is that the problem was
caused from the vasculature side, as the acting site of
nitroglycerin. It would be interesting to see if
anyone has attempted a similar test, but by direct
nerve stimulation, and with CH pain results.

Also, I think that based on this new theory it would
be hard to explain episodics' problems, perhaps
more so than chronic, since neurological damage is usually
so permanent. However, it is a sort of new twist,
with a totally different perspective on an old enemy.
5-HT may not be discounted all together from this
equation since it plays such an important role
in the CNS. Now, has anyone here come accross
any literature regarding the relationship between
5-HT and ion transport/action potentials/impulse generation
at the nerve level? (not at the vascular level).


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