Sebelium (flunarizine) for CH?


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Posted by John Graham on March 22, 1999 at 11:19:45:

I am also a sufferer of CH for the past 25 years (age 57). I am in the midst of another session after a three year break. I have just spoken to a freind who was treated with "Sebelium" (Flunarizine)for CH with good results. Has anyone else used this?

I looked it up and I see its used for treating AHC (Alternating Hemiplegia of Childhood) as well as for migraine. I Quote:

"Sibelium* CAPSULES
Selective Calcium-Entry Blocker
ACTION AND CLINICAL PHARMACOLOGY
SIBELIUM* (flunarizine hydrochloride) prevents the deleterious effects of cellular calcium overload by reducing excessive transmembrane fluxes of calcium. Flunarizine does not interfere with normal cellular calcium homeostasis. Flunarizine also has antihistaminic properties.

The effects of flunarizine in the prophylaxis of migraine are most pronounced with regards to the reduction of the frequency of attacks. The severity of migraine attacks improves to a lesser extent, while little or no effect is seen on the duration of migraine episodes."

End quote

I would be interested to hear from others before mentioning this to my docter.

John G





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