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Posted by Todd ( on March 10, 2001 at 19:29:52:

In Reply to: Made It To Three Stores Today... posted by Anxiety Dave on March 10, 2001 at 18:53:57:

Although CH isn't specifically mentioned, "severe headache types" are.

Migraine and Other Severe Headaches Comorbid With Panic Disorder

WESTPORT, CT (Reuters Health) Mar 05 - Persons with migraine or other severe headache types are at increased risk of panic disorder, and vice versa to some degree, according to analysis of data from the Detroit Area Study of Headache.

Through a random telephone survey, Dr. Naomi Breslau, of the Henry Ford Health System in Detroit, and colleagues identified 536 individuals with migraine and 162 individuals with other types of severe headache. Other severe headaches included tension-type headache, "migrainous disorder not fulfilling above (migraine) criteria," and other undiagnosed headaches.

Those with migraine were matched by age, sex, and race with 586 control subjects. The subjects were interviewed, with psychiatric disorders assessed by the Composite International Diagnostic Interview version 2.1. The investigators describe their analysis in the journal Neurology for February 13.

The odds ratio of panic disorder associated with migraine, after adjustment for sex and history of major depression, was 3.72 compared with controls. The corresponding odds ratio of panic disorder associated with severe headache was 2.95. Persons with migraine or severe headache had an increased risk for first onset of panic disorder, with hazard ratios of 3.55 and 5.75, respectively.

The authors also examined the relationships in the reverse direction, from panic disorder to first onset of migraine or severe headache. They found a lower risk, but of similar magnitude, for both, with hazard ratios of 2.10 and 1.85, respectively.

The investigators note that this is the first published report describing the relationship from panic disorder to first onset of migraine or severe headache.

Dr. Breslau's team posits that shared environmental or genetic factors appear to be involved in the comorbidity of panic disorder with these types of headaches. They suggest, "A diagnosis of migraine should heighten the clinician's index of suspicion for panic disorder and vice versa."

Neurology 2001;56:350-354.

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