dosage levels

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Posted by pinksharkmark ( on April 30, 2001 at 12:26:01:

In Reply to: Whoaaa....If this Verapamil doesn't work...... posted by JohnnyBGood on April 30, 2001 at 12:07:43:

Yes, it seems both from the clinical literature done in the fifties and sixties and from the reports here on this board that a full-on "recreational" trip is not required. Most of the episodics have managed to get complete relief from a single dose of either mushrooms or LSD that is equivalent to about one quarter to one third of a recreational dose.

In one case I know of, the person took about a TENTH of what is generally considered to be a "decent" recreational dose. She felt NOTHING at all... not even a giggle fit, yet her headaches still stopped.

She was the exception to the rule, though. It seems that most need about a gram or so of DRIED psilocybe cubensis. This is enough to give a minor buzz, but not enough to produce a "trip". Sort of the equivalent of a "two-beer buzz".

Dosing with LSD is more problematical, since the dosage level of today's blotters is wildly variable... averaging between 30 and 80 mcg. per blotter according to the DEA. The standard dosage level used in clinical headache studies in the Sixties was 25 mcg., so depending on the strength of your local product, it might take a complete blotter to do the trick, or a quarter of one. Individual sensitivity complicates the equation, too.

The bottom line is that it seems not to be necessary to get so twisted that your kitchen aplliances start talking to you, although if you choose to, that will stop the headaches, too. Underdosing may actually sometimes be more problematical than going full out, since some individuals report that a too-small dose doesn't eliminate the headaches but changes the frequency and/or duration of the headaches. In every case reported so far, though, a second, larger dose has fixed things.


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