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Posted by Bob P on November 17, 2001 at 16:25:09:

In Reply to: Has anyone taken Sansert? posted by Kathy R on November 16, 2001 at 23:20:59:

I tried it for one day. Felt like I was on the down elevator all day so I quit taking it. Here's what Doc Goadsby says about it:


Methysergide is a potent prophylactic agent for treating CH. It is an ideal choice in patients with short cluster bouts which last less than four to five months. Doses up to 12mg daily can be used if tolerated. Patients are started on 1mg once daily and the daily dose is then increased by 1mg every three days until the daily dose is 5mg. Thereafter, the dose is incremented by 1mg every five days.

Prolonged treatment has been associated with fibrotic reactions (retroperitoneal, pulmonary, pleural and cardiac), but these are rare. Although it is occasionally used in CCH, a drug holiday is necessary after every six months of treatment and neurological supervision entirely appropriate.

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