Posted by pinksharkmark (64.32.126.102) on August 08, 2001 at 23:29:33:
In Reply to: Imitrex: Another perspective . . . posted by Ken Hubner on August 08, 2001 at 20:34:13:
Imitrex (sumatriptan) was the first generation. The newer "second generation" triptan tablets (Maxalt, Zomig, Amerge) work at much lower dosages (typically 2.5 to 10 mg vs 50-100 mg) because they are much more narrowly focused. They tend to have less effect on heart functions.
As for the link between the triptans and psilocybin... both are based on the hallucinogenic precursor DMT (di-methyl tryptamine). DMT occurs naturally in very small quantities in the human brain. Imitrex (sumatriptan) is sulphonated DMT, psilocybin is phosporylated DMT.
And, actually, psilocybin is very easy on the heart.
For those who have reservations about potential side-effects from sumatriptan, I suggest looking into the alternatives -- Amerge, Maxalt, Zomig.
Or eat some mushrooms and be done with it.
pinky