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Topic: Imitrex SQ: reduced dosing (Read 261 times) |
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Bob_Johnson
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Imitrex SQ: reduced dosing
« on: Aug 23rd, 2005, 9:18am » |
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Headache. 2005 Sep;45( :1069-72.
Treatment of Cluster Headache Attacks With Less Than 6 mg Subcutaneous Sumatriptan.
Gregor N, Schlesiger C, Akova-Ozturk E, Kraemer C, Husstedt IW, Evers S.
Background.-Subcutaneous (SQ) sumatriptan 6 mg is effective in the treatment of acute cluster headache attacks. However, patients sometimes benefit from a dose less than 6 mg. Objective.-Therefore, we designed a prospective open study to evaluate how many patients benefit from a dose less than 6 mg SQ sumatriptan. Methods.-We enrolled 81 consecutive patients with cluster headache and recorded their use of SQ sumatriptan and oxygen. Patients regularly using SQ sumatriptan 6 mg were advised to treat attacks with doses less than 6 mg and with oxygen. Efficacy and side effects of the different treatment options (6 mg, 3 mg, 2 mg, and oxygen) were evaluated. Results.-As a result, 74% of the patients using SQ sumatriptan 3 mg showed efficacy and 89% reported efficacy after 2 mg. Seventy-nine percent reported side effects after the use of SQ sumatriptan 6 mg (29% severe side effects). After the use of 2 mg SQ sumatriptan, only 50% of the patients reported side effects, none of these were classified as severe. Patients' preference was 41% for 6 mg sumatriptan, 28% for doses less than 6 mg, and 31% for oxygen. Conclusions.-We conclude that sumatriptan in doses less than 6 mg can be effective in the acute treatment of cluster headache attacks. We suggest that patients should have experience in their individual efficacy of sumatriptan doses less than 6 mg. (Headache 2005;45:1069-1072).
PMID: 16109122
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Bob Johnson
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jcmquix
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Re: Imitrex SQ: reduced dosing
« Reply #1 on: Aug 23rd, 2005, 12:25pm » |
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Great Report Bob_Johnson !!!!
This really works !!!!!
PFDAN to ALL !!!
Charlie
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| « Last Edit: Aug 23rd, 2005, 12:26pm by jcmquix » |
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Would the owner of the propane torch, egg beater, pipe expander and vise grips please claim these items. They're lodged in my head and I need the space. (burnt-toast)
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LasVegas
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Episodic CH since 11 yrs old, now 39.
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Re: Imitrex SQ: reduced dosing
« Reply #2 on: Aug 23rd, 2005, 10:56pm » |
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Good post!
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Wishing all a Pain Free 2008!
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