Been on Topamax (generic) since June along w/ zero caffeine and have had very good results keeping beast at bay.  Have had some shadows here and there, but nothing to complain about. Wife has commented a few times about "good thing your on meds, you'd be having a good one tonight, your eye is all red and droppy".  But nothing ever happens.
   Started some Biaxin friday Jan 8th. 500mg 2x a day.  For an upper respitory infection i reackon.  Anyway tonight after work I feel  the beast coming on... scares the sheeite out of me.  I pop a hydrocodeine, which I don't abuse; and after about 10 minutes the beast leaves.  Never got above level 3.   
   Has anyone ever associated antibiotics and beast?  I take both topamax and Biaxin at same time in evening.  One of side effects of Biaxin is a headache.... But this was the beast.   jhk

Karla, I am one of the few rare people that actually get some relief from aspirin, ibuprophen over the years(lots of them(:>(  ).  The Hydro script was wrote in June for like 20 pills, I have over half left.  I have not been taking any aspirin or ibuprophen either.  I got on the topamax after the over the counter stuff quit working for me.  Actually, it did not work, it just gave me some relief.  I am aware of the O2. Not ready for it yet.  Last 6 months have been real good.