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Cluster after verapamil (Read 1566 times)
Mandarb
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Cluster after verapamil
Aug 23rd, 2016 at 9:36pm
 
Has anyone ever heard of getting a cluster within 1 to 2 hours of taking Verapamil? This is been happening to me for about a year and it is extremely consistent. I have no idea what to make of this.  Stopping the Verapamil causes my cluster to go Haywire so at least this is somewhat predictable. Thanks in advance.
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jon019
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Re: Cluster after verapamil
Reply #1 - Aug 23rd, 2016 at 11:49pm
 
Yes...it's been discussed in the far past here...no consensus....some don't believe.  Happened to me tho I could not discern a pattern like : when first starting, a certain dosage, empty-full stomach.... just very noticeable cause:effect

Since it was overall beneficial...and the after dosage hits generally lower level...I powered through and eventually it became less common...tho NOTE...I used dosages ranging from 480 mg/dy out of cycle and  up to 1040 mg/dy in cycle...

Several other  notes:

normal release better for most vs extended release

Should be regular ECG's after 6 months or after increasing dosage

monitor blood pressure

Eat lots of fiber and stay hydrated to prevent constipation

A prednisone or methylprednisolone titration (bout 2 weeks) to break the cycle until verap
kicks in (7-14 days)

Got oxygen?

Read here re the Vit D3 regimen

Best

Jon


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Mandarb
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Re: Cluster after verapamil
Reply #2 - Aug 24th, 2016 at 9:16am
 
Thanks Jon.

Yes, I do use oxygen.  Been chronic for 15 years now so I guess I'm an old pro now. 

Sadly, D3 doesn't work for me.  Tried it on 3 separate occasions.  What does work for me is cryoablation which thankfully I'm having done today.  Put me in remission for a year the first time I did it and the 2nd time (a year later) reduced the frequency to maybe 1 a week.

The headaches an hour after verapamil is something I've been toying with lately.  Changing the times I take the medicine by several hours and the clusters follow it around.  Very strange and just thought I would see if anyone had any thoughts.

In the last 24 hours, after increasing verapamil by 60mg per dose, the CH have stopped but it's only been a day so still testing.
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neuropath
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Re: Cluster after verapamil
Reply #3 - Sep 6th, 2016 at 5:19am
 
Yes. Definitely.

Has happened to me several times when reducing the dosage. Especially if you are on a high dose.

Like clockwork they appear 1h after taking my dose and the can quickly escalate to a 10. Tedious to abort with O2 and back after 30 min.

The only way to get rid of them is to up the dose again to original level. Takes up to 2 weeks to get back to "normal". Every time this has happened to me I use a zomig when taking the Verapamil. This keeps a lid on the verapamil induced attack. Careful with zomig rebound.

When reducing try a very slow taper. 40mg every 7-10 days.

For many here Verapamil is the holy Mary and although I admit that it's the only thing helping me it is not without downsides, this being one of them.

Not ideal by any means but under medical supervision and without coronary/cardiac pre-conditions Verapamil can also be stopped abruptly, without tapering.
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