Clusters vs Migraine

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Posted by Elaine ( on November 17, 1999 at 16:47:45:

In Reply to: Clusters vs Migraine posted by Tony on November 17, 1999 at 16:10:08:

This is what Dr. Goadsby and his team had to say about Cluster Headaches and Migraines:

"In contrast to Migraine, no brain stem activation was found during the acute attack compared with the resting state. This finding is remarkable because migraine and cluster headache are often discussed as asociated disorders and similar compounds, such as ergotamine and sumatriptan, are used in the acute treatment of both types of headache. These data suggest that while primary headaches, such as migraine and cluster headache, may share a common pathway (the trigeminovascular innervation), the underlying pathogenisis DIFFERS SUBSTANTIALLY as might be inferred from the different patterns of presentation to agents".

Dr. Goadsby's article also says that: "our findings establish central nervous system dysfunction in the region of the hypothalamus as the primum movens in the pathophysiology of cluster headache. We suggest that a radical reappraisisal of this type of headache is needed and that it should in general terms be regarded as a neurovascular headache, to give equal weight to the pathological and physiological mechanisms that are at work".

Hope this helps!! I copied this from a post that drummer posted a few weeks ago. Here is the link

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