This has absolutely nothing to do with the other issue of what NEEDS to be discussed with all docs involved (and I fully agree, no matter how scary...), but regarding solely anesthesia, pain medication and hits.
My PERSONAL experience has been that through all surgeries I have had since onset of both New Daily Persistent Headache (chronic migraine, for me) and CCH, I have had 1-2 weeks post-op of no CH and significantly reduced migraine. This was the case for EVERY SINGLE surgery except 2 sinus surgeries I had in 2005. I am convinced in those cases that it was the intranasal cocaine used in sinus surgery that triggered me to have some of the severest of attacks I've ever experienced, despite literature that shows cocaine to have abortive effects.
I had my most recent surgery on 9/9, and I didn't start having CH's and severe migraine until 9/19. 10 days! I was happy to have those 10 days because I had a lot of other stuff going on. After I got the stim implanted, I had a good while too. May have had more success after those surgeries than usual because they also use regional nerve blocks along with general anesthesia. BUT if it were only the nerve blocks, then I wouldn't have also experienced relief after my bilateral knee surgery in 2005, which I did. So it's a combination of things...
Jefferson tried using Propofol to abort intractable headaches back some years ago (2002-2003 maybe?) and eventually determined that there wasn't enough success. HOWEVER, in light of my near-PF time post-op after all surgeries but the sinus, I had a recent discussion about this with one of the NPs and she again referenced the Propofol as a possibility. It's a commonly used anesthetic. I don't know if it was used during my surgeries, but I suspect it probably was. Don't know if that's what is responsible for the near-PF time, but it may again have been a mixture of things.
In terms of post-op pain management, I have NEVER had worsening headaches from pain meds, although there are people here who will fight me tooth and nail over that statement, I know. It has been discussed at conferences (not sure if in literature) that some people are not susceptible to rebound or increased frequency of attacks secondary to analgesics (including opioids, OTC meds, NSAIDS, triptans, and so on, so forth...) After both stim implant and explant, I took Percocet (and at first, took 2 every 4 hours to get pain under control), and had no problems with headaches whatsoever. Now I'm down to taking aleve and occasional percocet (took 2 yesterday d/t post-op visit for suture removal...), and I'm still fine in terms of them not causing more headaches than usual. Am I back to having bad CH and bad migraine now that my post-op "heavenly near-PF phase" has worn off? Yes, but nothing more than usual.
For my ortho surgery - I was on PCA in hospital for first day or so post-op. Then due to side effects from the PCA, I was changed to oral percocet. Was also given a longer-acting pain medication so that I didn't have to wake all night long and take shorter acting pain meds - as was my brother after every single one of his ortho surgeries. I took the longer acting med (think it was oxycontin) for a week, then didn't need it any longer. Took the percocet for a little longer than that, but this was also because I was traveling and both legs had been operated on simultaneously. Nothing out of ordinary there, either. No more intense hits from pain meds. Never have.
So those are my PERSONAL experiences with head pain and anesthesia and pain meds. She's at least gotta go into the surgery with the mindset that she'll wake up feeling better. It doesn't help to fret over possibilities - but it DOES pay to be prepared. Have docs have O2 ordered ahead of time. After stim explant, neurosurgery resident ordered NRB mask and O2, and I ended up not needing it for entire stay bc of that post-op effect, but still I had it available to me. They also even ordered that I could take my own Frova or Amerge if I needed for severe migraine or CH. Those drugs weren't on formulary, but the pharmacy took them, examined them, and let me keep them in my room - on condition that I must tell RN if I needed to take it. Neurosurgery NP wrote for those provisions upon my speaking up. It pays to be proactive.
I will admit that I have had greater success when having neurologic surgery in terms of getting what I needed ordered. ENT refused to listen to a thing I said, put me on IV morphine q2 hours as needed (which I had never taken in my entire life at that point!), called me drug seeking because they offered me nothing else to relieve the pain, took me off all my headache meds because of the bleed I'd had, and after all that REFUSED to consult neurology. But with all respect to them, after my 1st sinus surgery when I had a SEVERE CH, plus vomiting up blood post-op, they did learn about and prescribe a shot of DHE upon my request.
She's going to need to speak up about what she needs to have ready for her in the event that she does wake up and has a CH or migraine. But she also needs (and you too!!) to have the mindset of hoping for the best, because it helps, even though it may not prevent the attacks from happening. Don't be afraid - Be prepared!!
And I cannot emphasize enough the importance of telling everything to all doctors involved. And honestly, nurses and pharmacists may even need to be kept in the loop as well. They are often the gatekeepers. Although patients themselves are the final gatekeeper of their own health, unfortunately.
I hope the surgery goes well and that she's feeling better soon!
Take care!
Carrie