You'll want to read over at

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Everything about that is right over there.

Well I know you're not suppose to have anything in you before you dose, but i'm not sure about after.  Do what Redd suggested.  Search in clusterbusters.  I'm detoxing of Imitrex right now to do another seed dose tomorrow night.  I needed trex to get through the work week.  I would suggest O2 if you can get it.  I'm having trouble at the moment getting O2 so I have been fighting the beast out with exercise, energy drinks and ice until i'm done dosing with seeds.
This cycle has been the easiest ever and I owe all my thanks to the seeds and clusterbusters.

twistedmuscle wrote on Sep 19^th, 2009 at 11:45am:


If your cycles are anything like mine, you'll wanna be on a preventative also.

Mine build intensity - the first week it is "easy" to abort the hits, then by week 3 or so they're coming in strong and 10 hits a day that I have to abort with hi LPM O2/imitrex. That's if my preventative isn't (Neuronitn) kicking in yet, which it wasn't this cycle.

Now the Neurontin seems to be working and the need for O2/imitrex is lessening some. This will save me if keeps up, as a preventative might save you.

Or maybe the mushrooms will have set the stage for a "milder" cycle for you....?

twistedmuscle wrote on Sep 19^th, 2009 at 11:45am:


you can use the o2 with the shrooms. the use of trex with probably cancel out the shrooms. i've always gotten the permanent results from busting a few weeks after the treatment

Monika wrote on Jan 12^th, 2010 at 2:29am:

This is the hardest part about dosing on any of the hallucinogens.  Meaning, taking a couple of hits for the detox to take place.  You'll need to detox from triptans for the most effectiveness of the LSD.

Here's a good old copy and past job from Clusterbusters.  I suggest you save and read everything on that site.

4.1.2 Possible inhibitors

There are some medications which may interfere with psilocybin (and LSD):

    * anti-convulsants or anti-epileptic medications such as Neurontin(gabapentin) and Topamax(topiramate). The exact mechanism by which topiramate works, for example, is still unknown, so it is impossible to even guess whether or not it will interfere with psilocybin.
    * medications which are either synthetic analogs of certain hormones or which regulate hormone production: Prednisone and Synthroid, for example. There is no direct evidence to suggest that these drugs will interact with psilocybin, but hormones have a very complex and inter-related effect on numerous body systems. We have seen a few reports suggesting that thyroid levels play a part in cluster headaches
    * tranquilizers and mood-altering medications such as Xanax, Valium, Prozac and Wellbutrin.
    * Ondansetron (Zofran) and Compazine (prochlorperazine)

    * * Imitrex (and associated triptans):
      Based upon many reports, triptans are one of the most likely medications to block the clusterbusting effects of psychedelics. In our opinion, they should be avoided both before, during and after, beginning psychedelic treatments for clusters.

   1. sumatriptan (Imitrex®, Imigran®) injections
   2. sumatriptan (Imitrex®, Imigran®) tablets
   3. zolmitriptan (Zomig®) tablets
   4. sumatriptan (Imitrex®, Imigran®) nasal spray
   5. naratriptan (Amerge®, Naramig®) tablets
   6. rizatriptan (Maxalt®) tablets and rizatriptan orally dissolvable (Maxalt-MLT®) tablets
   7. zolmitriptan orally dissolvable (Zomig-ZMT®) tablets
   8. almotriptan (Axert®) tablets
   9. frovatriptan (Frova®) tablets
  10. eletriptan (Relpax®) tablets

Related Articles, Links
Headache. 2004 Jul;44(7):713-8.
Subcutaneous sumatriptan induces changes in frequency pattern in cluster headache patients.
Rossi P, Lorenzo GD, Formisano R, Buzzi MG.

Objectives.-To document the relationship between the use of subcutaneous (SQ) sumatriptan (sum) and a change in frequency pattern of cluster headache (CH) in six patients. To discuss the clinical and pathophysiological implications of this observation in the context of available literature. Background.-Treatment with SQ sum may cause an increase in attack frequency of CH but data from literature are scant and controversial. Methods.-Six CH sum-naive patients (three episodic and three chronic according to the International Headache Society (IHS) criteria) are described. Results.-All six patients had very fast relief from pain and accompanying symptoms from the drug but they developed an increase in attack frequency soon after using SQ sum. In all patients, the CH returned to its usual frequency within a few days after SQ sum was withdrawn or replaced with other drugs. Five patients were not taking any prophylactic treatment and SQ sum was the only drug prescribed to treat their headache. Conclusions.-Physicians should recognize the possibility that treatment of CH with SQ sum may be associated with an increased frequency of headache attacks.

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Monika wrote on Jan 12^th, 2010 at 2:29am:


lots of good information in this thread. i would suggest some non rx abortives
-ice water treatment
-lots of o2 (flow rate of 15 LPM or higher)
-caffeine (red bull, coffee)
-cold air
-physical activity (running, jumping jacks, chopping wood, punching bag, ect)
-hot or cold showers
-kudzo
-melatonin (for sleep)

getting through detox is going to be tough but it can be done.

i've been episodic for 22 years and i've never used any kind of prescription drugs for cluster headaches    

heres a link to the clusterbuster message board
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