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123 Days PF And I Think I know Why (Read 532397 times)
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Re: 123 Days PF And I Think I know Why
Reply #500 - Dec 21st, 2011 at 2:36pm
 
Regarding D3 dosing:  Dr. John Cannell at the Vitamin D Council states the general rule:

... proper maintenance dosage(25mcg (1,000 IU/10 kg per day)

From this recent article:
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Re: 123 Days PF And I Think I know Why
Reply #501 - Dec 21st, 2011 at 3:37pm
 
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Hi nhs.  I know D3 will heighten the uptake of Ca. But what is the role of Mg here?  Why imbalance, and what is the effect?


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Re: 123 Days PF And I Think I know Why
Reply #502 - Dec 21st, 2011 at 11:21pm
 
nhs wrote on Dec 21st, 2011 at 7:06am:
But with 10.000 IU of vitamin-D3 and a normal diet most people get all the calcium needed

Define "Normal Diet". I would assume, from the people I know, that "Most" people don't even drink milk anymore.

I don't think its wise to Generalize "Most People", and I don't see the point in arguing that a Calcium supplement is unnecessary. If you feel its unnecessary, don't take it, simple as that.
1000 mg/day calcium is quite a bit, and considering vitamin D3 will drive more calcium from the gut into solution than normal its seems logical that a Calcium supplement IS necessary in most circumstances.

Even if its not necessary, its understandable that its recommended. All supplements are "Unnecessary" if your diet is sufficient, its up to you to determine if you should take one or not.
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Re: 123 Days PF And I Think I know Why
Reply #503 - Dec 22nd, 2011 at 7:43am
 
If you are low in vitamin-D, only 20-30% of the diet calcium is absorbed from the gut, so when the vitamin-D level increases, the calcium absorption will increase the absorption from the remaining 70-80% calcium from your diet. Vitamin-D sufficiency may be more important than high calcium intake in maintaining desired values of serum PTH. Vitamin-D have a calcium sparing effect and as long as vitamin D status is ensured, calcium intake levels of more than 800 mg/d may be unnecessary for maintaining calcium metabolism. So taking vitamin-D, don't need extra calcium from supplement, if your diet contains 800 mg of calcium.
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Re: 123 Days PF And I Think I know Why
Reply #504 - Dec 22nd, 2011 at 10:39am
 
Im heading to the doc tomm to get routing bloodwork done for high cholesterol.

I can use this opportunity to get other things measured which you are interested in.

I just started this regimen three days ago.  What specific things would you guys be interested in seeing as far as bloodwork goes?
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Re: 123 Days PF And I Think I know Why
Reply #505 - Dec 22nd, 2011 at 1:39pm
 
bsic wrote on Dec 22nd, 2011 at 10:39am:
What specific things would you guys be interested in seeing as far as bloodwork goes?

25(OH)D serum levels


25-hydroxy vitamin D test

The 25-hydroxy vitamin D test is the most accurate way to measure how much vitamin D is in your body.

In the kidney, 25-hydroxy vitamin D changes into an active form of the vitamin. The active form of vitamin D helps control calcium and phosphate levels in the body.

This article discusses the blood test used to measure the amount of 25-hydroxy vitamin D.
How the Test is Performed

Blood is typically drawn from a vein, usually from the inside of the elbow or the back of the hand. The site is cleaned with germ-killing medicine. The health care provider wraps an elastic band around the upper arm to apply pressure to the area and make the vein swell with blood.

Next, the health care provider gently inserts a needle into the vein. The blood collects into an airtight vial or tube attached to the needle. The elastic band is removed from your arm.

Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.

In infants or young children, a sharp tool called a lancet may be used to puncture the skin and make it bleed. The blood collects into a small glass tube called a pipette, or onto a slide or test strip. A bandage may be placed over the area if there is any bleeding.
How to Prepare for the Test

Do not eat for 4 hours before the test.
How the Test Will Feel

When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.
Why the Test is Performed

This test is done to determine if you have too much or too little vitamin D in your blood.
Normal Results

The normal range is 30.0 to 74.0 nanograms per milliliter (ng/mL).

Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.

The examples above show the common measurements for results for these tests. Some laboratories use different measurements or may test different specimens.
What Abnormal Results Mean

Lower than normal levels suggest a vitamin D deficiency. This condition can result from:

    Lack of exposure to sunlight
    Lack of adequate vitamin D in the diet
    Liver and kidney diseases
    Malabsorption
    Use of certain medicines, including phenytoin, phenobarbital, and rifampin

Low vitamin D levels are more common in African-American children, particularly in the winter, as well as in infants who are exclusively breastfed. Low vitamin D levels have also been associated with an increased risk of developing cancer. For more information, see the article on vitamin D deficiency.

Higher than normal levels suggest excess vitamin D, a condition called hypervitaminosis D.
Risks

Alternative Names
25-OH vitamin D test; Calcidiol 25-hydroxycholecalciferol test

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Re: 123 Days PF And I Think I know Why
Reply #506 - Dec 22nd, 2011 at 4:18pm
 
Question for Batch or anyone.. I've been on a Fish Oil Regimen for a while for joint issues. My doctor recommended taking supplements that would provide betwen 3 and 4 grams combined of omega 3's. This requires much higher doses than recommended as part of this regimen. (I typically take between 2 and 3 grams of Omega 3's).   My question is whether taking significantly more fish oil would have any known negative consequence to this regimen?   

Background:  Longtime reader though i don't post much. Just entering a cycle.. Sad I've been episodic sufferer with fairly consistent timing over the past 20 years typically early fall to early spring onset, usually one cycle a year lasting 10-14 weeks. As usual, i start getting hit and i come back to this wonderful board because it's the only place i feel like there is any understanding... and as always i feel a little guilty about having been away.  I'm determined to fight this latest cycle with all known natural treatments (that i can actually get) before going the way of prednisone, etc. I'm excited to try this regimen, and am just wondering if upping the fish oil portion presents any known problems?
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Re: 123 Days PF And I Think I know Why
Reply #507 - Dec 22nd, 2011 at 5:26pm
 
Cosworth

Hi.  I don't think your amount of Omega 3 will have any negative effect on the regimen. If any effect, a positive is more likely.

I think it's very common to be on-board when in cycle and the gradually get off-board  Smiley

I really hope the regimen works for you.  Very interesting that your cycle has just begun, because if the regimen kicks in, you'll know it's not the regular end of cycle.  Good luck!

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Re: 123 Days PF And I Think I know Why
Reply #508 - Dec 22nd, 2011 at 6:12pm
 
I started off taking 4000 MG (4 Grams) of Omega 3, but now in the name of conservation I take 3000 or 3 pills.

The Omega 3 I have is "select" and it has a higher concentration of EPA and DHA then most, I assume. Batch recommends EPA 360 mg/day, DHA 240 mg/day from 2000 to 2400 mg/day of fish oil a day.

My Omega 3 have 500 mg of Omega 3 (EPA 300 and DHA 200) from 1000 mg of fish oil, in each pill. I take 3 now, but took 4 a day for a week

So I'm taking EPA 900 and DHA 600, and took EPA 1200 and DHA 800 with no ill effects at all. I'm sure my bad Cholesterol took a good hit, and is still getting reduced, which can only be a good thing.

Just an early calculation by me, seems that around 75% of people find it works for them, and a good portion of those are PF. Give it a fair try and theres a good chance it will help, and even if not, it does a body good.  Wink
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Re: 123 Days PF And I Think I know Why
Reply #509 - Dec 23rd, 2011 at 3:01am
 
NHS,

I suspect we're in violent agreement.  The basic anti-inflammatory regimen I developed calls for the Kirkland brand of calcium citrate as it is formulated with additional vitamin D3, magnesium and zinc, along with the trace minerals copper and boron to help maintain electrolyte homeostasis. 

When I ran this regimen by some of the leading experts in vitamin D3 therapy, it got a green light and a suggestion to add more magnesium...  which I have done with the "complete" version of this regimen by adding 400 mg. magnesium citrate or magnesium gluconate.  This brings the calcium-magnesium ratio close to 1:1, so there should be no imbalance for most CH'ers who use this regimen unless they have other medical problems listed below.

There's no clear consensus as to the ideal ratio of calcium to magnesium when it comes to taking these two supplements, save for a range of 4:1 to 1:1.  In addition, the Linus Pauling Institute for Micronutrient Research for Optimum Health suggests that adults 31 years and older have an RDA for magnesium equal to 420 mg/day for men and 320 mg/day for women.  They site a study where 600 mg/day magnesium helped prevent migraines. For reference, the IOM RDIs for magnesium in this same age group are 420 mg/day for men and 320 mg/day for women.  From my own experience, taking too much magnesium is easy to spot... as going over these values can result in osmotic diarrhea.

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The Linus Pauling Institute also contends:


"The active form of vitamin D [calcitriol - 25(OH)D] may slightly increase intestinal absorption of magnesium. However, magnesium absorption does not seem to be calcitriol-dependent as is the absorption of calcium and phosphate. High calcium intake has not been found to affect magnesium balance in most studies. Inadequate blood magnesium levels are known to result in low blood calcium levels, resistance to parathyroid hormone (PTH) action, and resistance to some of the effects of vitamin D."

"Magnesium deficiency in healthy individuals who are consuming a balanced diet is quite rare because magnesium is abundant in both plant and animal foods and because the kidneys are able to limit urinary excretion of magnesium when intake is low. The following conditions increase the risk of magnesium deficiency:

Gastrointestinal disorders: Prolonged diarrhea, Crohn's disease, malabsorption syndromes, celiac disease, surgical removal of a portion of the intestine, and intestinal inflammation due to radiation may all lead to magnesium depletion.

Renal disorders (magnesium wasting): Diabetes mellitus and long-term use of certain diuretics (see Drug interactions) may result in increased urinary loss of magnesium. Multiple other medications can also result in renal magnesium wasting.

Chronic alcoholism: Poor dietary intake, gastrointestinal problems, and increased urinary loss of magnesium may all contribute to magnesium depletion, which is frequently encountered in alcoholics.

Age: Several studies have found that elderly people have relatively low dietary intakes of magnesium. Intestinal magnesium absorption tends to decrease with age and urinary magnesium excretion tends to increase with age; thus, suboptimal dietary magnesium intake may increase the risk of magnesium depletion in the elderly."


Finally, this is a therapeutic regimen.  There is more than sufficient medical evidence to prove that a dose of vitamin D3 at 10,000 IU/day will result in a safe and stable level of 25(OH)D... ~ 90 ng/mL, (225 nmol/L) if the starting level is 26 ng/mL, (65 nmol/L).  At these levels, supplemental calcium and magnesium are prudent as are the other vitamin D3 cofactors. 

The only way to know for sure if this regimen is suspected to be creating an imbalance is to have a Chemistry Panel & Complete Blood Count (CBC) lab test done along with the test for 25(OH)D.  The test for Parathyroid Hormone (PTH) might also be a good idea as PTH plays a significant role in calcium homeostasis.

Hope this helps...

Take care,

V/R, Batch
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Re: 123 Days PF And I Think I know Why
Reply #510 - Dec 23rd, 2011 at 4:49am
 
Hey Cosworth,

The amount of Omega 3 Fish Oil you're taking should work just fine without any problems.  I originally started this regimen with 3000 to 4000 mg (3 to 4 grams) of Omega 3 Fish Oil but dropped the dose to 2000 - 2400 mg/day to keep things simple when it appeared that amount worked just as well.

Please keep us posted on your results.  The survey of this regimen indicates CH'ers start experiencing a marked reduction in the frequency and severity of their CH in less than 24 hours to 10 days and most are pain free before the end of the third week.

Take care,

V/R, Batch
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Re: 123 Days PF And I Think I know Why
Reply #511 - Dec 23rd, 2011 at 5:49am
 

Magnesium:
A Key to Calcium Absorption

By Nan Kathryn Fuchs, Ph.D.



One of the most popular minerals in the news today is calcium, needed for strong bones and teeth. We are told to take increased amounts in our diet as a supplement to prevent osteoporosis and eliminate muscle cramping during menstruation or from over-exercising. Yet, calcium alone is often not enough. Without magnesium, calcium may be not fully utilized, and underabsorption problems may occur leading to arthritis, osteoporosis, menstrual cramps, and some premenstrual symptoms.

Perhaps the single most significant reason calcium malabsorption is so common today is due to a discrepancy between what we eat and how we digest and absorb the nutrients in our food. Our diets today are very different from those of our ancestors though our bodies remain similar.

Thousands of years ago, our ancestors ate foods high in magnesium and low in calcium. Because calcium supplies were scarce and the need for this vital mineral was great, it was effectively stored by the body. Magnesium, on the other hand, was abundant and readily available, in the form of nuts, seeds, grains, and vegetables, and did not need to be stored internally.

Our bodies still retain calcium and not magnesium although we tend to eat much more dairy than our ancestors. In addition, our sugar and alcohol consumption is higher than theirs, and both sugar and alcohol increase magnesium excretion through the urine. Our grains, originally high in magnesium, have been refined, which means that the nutrient is lost in the refining process. The quality of our soil has deteriorated as well, due to the use of fertilizers that contain large amounts of potassium a magnesium antagonist. This results in foods lower in magnesium than ever before.


ARTHRITIS AND OSTEOPOROSIS

Two major health problems, arthritis and osteoporosis, may be caused in part by a magnesium deficiency. When you look at how calcium is absorbed these problems become easier to understand, and often can be controlled through diet.

Magnesium is needed for calcium absorption. Without enough magnesium, calcium can collect in the soft tissues and cause one type of arthritis. Not only does calcium collect in the soft tissues of arthritics, it is poorly, if at all, absorbed into their blood and bones. But taking more calcium is not the answer; it only amplifies the problem. In fact, excessive calcium intake and insufficient magnesium can contribute to both of these diseases. Magnesium taken in proper dosages can solve the problem of calcium deficiency.

When calcium is elevated in the blood it stimulates the secretion of a hormone called calcitonin and suppresses the secretion of the parathyroid hormone (PTH). These hormones regulate the levels of calcium in our bones and soft tissues and are, therefore, directly related to both osteoporosis and arthritis. PTH draws calcium out of the bones and deposits it in the soft tissues, while calcitonin increases calcium in our bones and keeps it from being absorbed in our soft tissues. Sufficient amounts of magnesium determine this delicate and important balance.

Because magnesium suppresses PTH and stimulates calcitonin it helps put calcium into our bones, preventing osteoporosis, and helps remove it from our soft tissues eliminating some forms of arthritis. A magnesium deficiency will prevent this chemical action from taking place in our bodies, and no amount of calcium can correct it. While magnesium helps our body absorb and retain calcium, too much calcium prevents magnesium from being absorbed. So taking large amounts of calcium without adequate magnesium may either create malabsorption or a magnesium deficiency. Whichever occurs, only magnesium can break the cycle.

In experiments reported in "International Clinical Nutrition Review," a number of volunteers on a low-magnesium diet were given both calcium and vitamin D supplements. AU the subjects were magnesium-depleted and although they had been given adequate supplements, all but one became deficient in calcium. When they were given calcium intravenously, the level of calcium in their blood rose, but only for the duration of the intravenous feeding. As soon as the intravenous calcium was stopped, the levels calcium in the blood dropped. However, when magnesium was given, their magnesium levels rose and stabilized rapidly, and calcium levels also rose within a few days - although no additional calcium had been taken.

Dr. Guy Abraham, M.D., a research gynecologist and endocrinologist in premenstrual syndrome and osteoporosis has found strong evidence to suggest that women with osteoporosis have a deficiency of a chemical that is made when they take twice as much magnesium as calcium. In fact, he has found that when calcium intake is decreased, it is utilized better than when it is high. Dr. Abraham is one of many doctors and biochemists who advocate taking more magnesium to correct calcium-deficiency diseases.

A magnesium-rich diet can be helpful both for arthritis and to help prevent osteoporosis. This consists of nuts, whole grains such as brown rice, millet, buckwheat (kasha), whole wheat, triticate, and rye, and legumes including lentils, split peas, and a varieties of beans. A whole grain cereal or bread in the morning, a cup of bean soup at lunch, a snack of a few nuts, and serving of brown rice, millet, or buckwheat with dinner should help increase magnesium when a deficiency is suspected
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Re: 123 Days PF And I Think I know Why
Reply #512 - Dec 26th, 2011 at 1:00pm
 
Hey Batch,

Thanks for the info and reply - I've been away from my computer due to the holidays but I do have some interesting news to report. You mentioned a survey so if there is somewhere else i should be updating results let me know.  So,  I started the regimen (minus the magnesium which I still need to pick up) the day after i posted which was the 23rd i believe. As I mentioned, I am 99% sure as a long time CH sufferer that i was entering my cycle.  My cycles are pretty good bell curves with the beginnings having major shadowing which typically noticeable all day punctuated with minor clusters kip 1-3 that don't last a long time. My cycles progress to where in the peak weeks I'm usually getting hit 3-5 times a day with CH (kip 6-9) that typically last 1-1.5 hrs. with no O2.  Since discovering O2 about 5 yrs ago i get my e tanks filled and have pretty good success aborting within 20-30 minutes (usually).  Anyway, I am not sure but I think I have noticed a reduction in the shadowing since starting this regimen a few days ago. I'm still having shadows, but they don't seem to be progressing as i would normally expect them to.  In addition, i've done something the last couple of nights that i typically could never do once a cycle started which is have a couple of  drinks each of the last three nights.  Having a cycle start up right before the holidays when I am finally getting a few days off work and looking forward to a little festivity with the family was a real bummer and i guess in my own stupid way to defy the beast i decided i was going to make the beast prove he was back before deciding it was time to go on my yearly 3 month alcohol-free period.  (Alcohol always been a sure-fire trigger for me).  I'm very excited by the results i've read about and am really hoping it works for me.  I temper this with the knowledge that i have had cycles begin as usual with shadowing, etc. and then for inexplicable reason stop.. and wait a month or so and then begin again for real.  That's why i said i was 99% sure my cycle had begun. Usually once the heavy shadowing is at hand it's a done deal that i'm going to begin a cycle.   So, I just wanted to say thanks. Like so many others, anything that offers some hope to stop these @#% CH's is truly a Godsend.  I'm curious if other Episodic sufferers have been able to eliminate cycles completely to where this regimen has actually "busted" a cycle?
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Re: 123 Days PF And I Think I know Why
Reply #513 - Dec 27th, 2011 at 6:06pm
 
Week 5. Just upped to 20,000 IU D3 at Batch's suggestion. Was chronic, 6+ per day up to Kip 8-10. Almost vanished during the day. Still have a 1 AM and 4 AM hit at about Kip 3-4. Remarkable improvement!
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Re: 123 Days PF And I Think I know Why
Reply #514 - Dec 27th, 2011 at 9:30pm
 
Hi All,
Has anyone considered adding B2 (Riboflavin) to the regimen?  I've noticed a lot of information online that it can help with migraine headaches.  I wonder if it would have the same effect for clusters?  Maybe adding B2 would help those who have been able to achieve a reduction in intensity but not able to go pf actually go pf.   
I've been in cycle for the last two months and on the D3 treatment for the last two weeks.  The reduction in intensity of the beast has been amazing.  I had a hit this morning and actually debated with myself if I needed to take an abortive to kill it or just live with it.  I'm hoping that a third week on the D3 I will be able to achieve pf status. 

Second question for the group.  How important is the vitamin K for the regimen?  I am unable to find it in Canada.  I don't think the government allows the sale of it. 
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Re: 123 Days PF And I Think I know Why
Reply #515 - Dec 28th, 2011 at 12:20am
 
MM&I, 69Strat, Cosworth,

Your responses so far are what I've come to expect.  Not sure how much effect vitamin K has on all this, but it's becoming clear magnesium is essential to metabolize vitamin D3 into 25(OH)D effectively.  If you haven't added extra magnesium to bring the total supplement up to ~ 400 mg/day magnesium, do so...

From the data collected so far, it appears this regimen is equally effective for episodic and chronic CH'ers.

Hang in there the three of you and I'm sure you'll find the response to this regimen will improve even more...

Take care,

V/R, Batch
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Re: 123 Days PF And I Think I know Why
Reply #516 - Dec 30th, 2011 at 1:00am
 
Batch,  I know you are a busy person helping many people who post here as I am also a busy guy with work and all.  So I will try to summarize as best as I can.  I started multiple treatments at the same time Lithium @ 900 mg p/d, 120 mg pred taper, 2 occipital nerve blocks, 10 MG melatonin at bedtine, and your regimine.  For that reason I am not able to complete the survey as I dont know what works.  I am still on the lithium and your regimin.  I also was able to find the K2 but am not taking the full dose as it is really expensive.   After starting all of those treatments my CH's halted quite rapidly.  I believe without checking my records that it was day 4 or 5 of the pred taper (3 days at 120 mg then taper by 10 mg P/d) and day 2 or 3 of the 123 regimin. 

I have been HA free for 16 days.  However I have been having daily what I believe to be some sort of non developing sinus infection/pressure that OTC meds seem to help with.  I dont seem to have many of the other symptoms of a sinus infection and it is also pressure that switches sides.  I do have a bit of a cough but basically no other symptoms. 

Tonight as I have tomorrow off I decided to give the whiskey test a try.  I feel as though I am shadowing but it is still very strange.  As I palpate my right eye (cluster side) it is much more sensetive than the left.  That coupled with the sinus pressure if that indeed is sinus pressure I am going to guess that I am not out of cycle yet and either the 15000 IU of D3 regimine or the lithium is doing its job.  I will update you tomorrow if I get hit while sleeping but I am crossing my fingers.  I am also thinking of upping the D3 to 20000 IU to see what happens there.  I am also going to schedule an appt with my GP to see if I should go on some antibiotics to see if that clears up the sinus pressure.  That pressure is deffinetly different than CH pain.  Again though it doesnt seem to be getting better or worse.  When I do have that appointment I will get my 25 OH D3 levels checked to report back to you. 

Additionally todays "vodka" test included several "rounds" of theraputic treatment.  Much needed as this is a very stressfull time of the year at work.   Wink 

Your input is welcome but I basically wanted to update you regarding my progress with this bout.  I am episodic with 2+ yrs between bouts.  32 YOA and this is my 5th diagnosed bout. 

Thanks again and boy do I hope that your D3 research leads to more CH research and perhaps someday an effective treatment for all.  (Insert C word) Grin 

Eric

P.S. Shout out to NHS as well.  I read "The CH cure?"  Pretty strong opposition over something that in the long run seems to be a breakthrough for many.
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Re: 123 Days PF And I Think I know Why
Reply #517 - Dec 30th, 2011 at 6:03pm
 
Hey Eroc.

Thanks for the wonderful post.  I'll try to be objective in my assessment of your present CH response to all the med's you've taken and are presently taking...  However, as I have a dog in the fight...  I'm sure some folks will still say I'm biased.

There's a simple and easy way to prove what's working... and what isn't...  between the lithium carbonate and the anti-inflammatory regimen in preventing your CH...  I've already tried the following stress test just to prove it to myself...

Stop taking the anti-inflammatory regimen...  My guess is within 24 to 48 hours you'll have depleted the reserves of 25(OH)D you've built up and be back in a high CH cycle with a solid CH hit...

Not to worry...  At the first sign of a hit, gobble down the regimen with the 20,000 IU/day vitamin D3 you were taking and bite down on a couple of the vitamin D3 softgel capsules to release the contents into your mouth and under your tongue for 30 seconds then wash it down with some juice or water. 

If your CH behave like mine...  you'll abort the hit in short order... like in less than 20 minutes with some deep breathing, and go back to being pain free...

After that... you and your doctor can decide what to do about whether or not to continuing taking the lithium carbonate...  As good as lithium carbonate can be for some CH'ers...  the odds are it wasn't responsible for your going pain free so rapidly...

You can wait until the new year before to try this stress test just in case I'm wrong about how fast you'll respond to the resumption of the anti-inflammatory regimen...  no sense in putting some good drinking time at risk on my count... 

When you're done with this stress test and have your 25(OH)D level tested... you can take the anti-inflammatory survey and provide us with your results...  one way or the other...

I've already got the results of your stress test sealed in an old Mayonnaise jar buried out by the woodshed.

Take care, have a pain free Happy New Year...  and please keep us posted...

V/R, Batch
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Re: 123 Days PF And I Think I know Why
Reply #518 - Dec 30th, 2011 at 6:36pm
 
Pill (tablet) vs Soft-gel? At my local Wally-World they had Vitamins for 40% off, but there tablets. I asked the same Pharmacist who was less then helpful last time I ask, and he said that it wouldn't matter.

I asked him if I was taking them everyday, if it would really matter, since he said that the soft-gels are faster acting. I figured since my levels should be good when I'm done with the soft-gels, tablets should be good to 'maintain' my levels.

I thought of maybe taking half soft-gel, half tablet also.

Any thoughts?
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Re: 123 Days PF And I Think I know Why
Reply #519 - Dec 30th, 2011 at 6:43pm
 
Eroc wrote on Dec 30th, 2011 at 1:00am:
I have been HA free for 16 days.  However I have been having daily what I believe to be some sort of non developing sinus infection/pressure that OTC meds seem to help with.  I dont seem to have many of the other symptoms of a sinus infection and it is also pressure that switches sides.  I do have a bit of a cough but basically no other symptoms.  


I'm not drawing conclusions, yet it may be worth noting that I also got an infection right after starting the regime. I got a bad ear infection, almost the day after starting. That might be too soon to be a result of, yet I haven't had a ear infection in almost 20 years.

I did have a mild cough for about a week after my ear cleared up, and even brought up some Flem, which would suggest mild bronchitis. Yet it was only once I coughed it up, and I've been infection free for a couple weeks now, and still PF.  Grin

Perhaps a mild infection is a possible side-effect?

I joked that the CH demon made his last stand in my ear before he got evicted from my head. lol. Well worth the trouble, either way.

I'm glad your getting relief also.
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Re: 123 Days PF And I Think I know Why
Reply #520 - Dec 30th, 2011 at 9:25pm
 
PlayDoh, Eroc,

Regarding the congestion, coughing, ear infection and sinus squeeze...  Cause and coincidence are two different animals...  I've not seen anything about the above conditions in the literature about vitamin D3 except to use it as a treatment or preventative for them.

There is a slight possibility of a mild allergic reaction to the vitamin D3.  This is relatively rare and you would have already known about it long before taking any vitamin D3 as you would be allergic to the UVB in sunlight.  In short you would experience some kind of skin reaction with itching, inflammation, swelling and blisters nearly every time your skin was exposed to direct sunlight for more than a few minutes.

Signs of an allergic reaction to vitamin D3 supplements would include: hives; difficulty breathing; swelling of your face, lips, tongue, or throat...  If you experience any of these symptoms, stop taking the entire anti-inflammatory regimen and see your doctor or PCP.

There's an easy way to see if you're having an allergic reaction to cholecalciferol...  Take a ball-point pen and draw a half-inch diameter circle on the inside of your forearm six to eight inches up from the wrist.  Then cut the tip off of a vitamin D3 softgel capsule and squeeze a drop into the circle.  Rub it in with a Q-tip or clean cotton ball and check it after 24 to 48 hours...  If you're using a tablet form of vitamin D3 crush a tablet between two spoons and add a few drops of water to make a paste then take a Q-tip and dab a bit of the paste in the circle and rub it in.

Signs of an allergic reaction would be redness and a slight swelling of the skin inside the circle. 

Now... before someone goes hyper over this...  there are any number of skin creams and lotions available that are formulated vitamin D3...  Again, see your PCP or neurologist if you think you're having an allergic reaction

PlayDoh... regarding tablets or liquid softgel forms of vitamin D3...  Your WallyWorld pharmacist is correct.  The liquid softgel capsules go into solution much faster... 

Having said that... we're talking vitamin D3 for its preventative effect and not as an acute treatment/abortive...  In this case we're taking enough vitamin D3 (cholecalciferol) so our body can metabolize it into its primary metabolite, 25(OH)D for use and storage to build up reserves...

Think about vitamin D3 and 25(OH)D as being akin to a bear eating lots of salmon during the summer and getting fat...  During the winter when the bear hibernates...  his body burns the fat. 

We do much the same thing with the 25(OH)D.  During the winter months when we can't get exposed to sufficient sunlight while clad in a bathing suit w/o sun block to make more vitamin D3...  so our liver and kidneys can metabolize it into 25(OH)D...  we burn our reserves of 25(OH)D.

Hope this helps.

Take care,

V/R, Batch
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Re: 123 Days PF And I Think I know Why
Reply #521 - Dec 30th, 2011 at 10:48pm
 
10 days in and actually have been seeing an increase in frequency and intensity. Sad. Still keeping the faith and taking the regimen daily
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Re: 123 Days PF And I Think I know Why
Reply #522 - Dec 30th, 2011 at 11:37pm
 
Thanks Pete.

bsic
Hang in there, it could take 30 days or more to get your levels right, and start to notice any effect.

Perhaps you might consider increasing your D3 intake to say, 15000 or 20,000 IU as I've read others have done. I'm sure Batch will advise you on the matter, if prudent. If he has the time, that is.
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Re: 123 Days PF And I Think I know Why
Reply #523 - Dec 31st, 2011 at 8:14pm
 
Just got my blood work back from last week.  When I got it tested last week, a few days into the regimen, my D levels were at 20!
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Re: 123 Days PF And I Think I know Why
Reply #524 - Dec 31st, 2011 at 10:12pm
 
bsic wrote on Dec 31st, 2011 at 8:14pm:
Just got my blood work back from last week.  When I got it tested last week, a few days into the regimen, my D levels were at 20!

Was the 25(OH)D concentration in ng/mL or nmol/L?  In either case you're deficient in vitamin D3...  Big Time!

Check your PM InBox tomorrow morning.

Take care,

V/R, Batch

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