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an herbal option that works (Read 10233 times)
lgenser
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an herbal option that works
Dec 14th, 2010 at 10:50pm
 
Hi. I am new to your forum and site having been "off the grid" for quite a while. I have suffered CH for 37 years, mostly episodic but for the last two years chronic. My story is probably really familiar to everyone here, but I have something I believe is important to share. I am what you would call a lay herbalist; I have helped lots of people, dogs, cats and horses but I was never able to do anything for myself. About a year ago I embarked on a search for a truly effective herbal analgesic, since I dislike and distrust pharmaceuticals (having tried just about all up to and including opiates). I didn't find one, which is probably no surprise to most of you. No known analgesic works at all on clusters, and that should have been a clue, but anyway:- I will cut to the chase as my research makes for a thrilling tale which I would love to share but it is quite besides the point.
I finally found what I was looking for in an herb I had previously used mostly for cases of depression or liver damage: licorice root.
Glycyrrhiza glabra is an herb of truly ancient medicinal pedigree with many and varied virtues. I could go on at length about this stuff, but here is what is pertinent: Licorice root contains isoflavans, completely unique phytoestrogens (demonstrated in an Israeli University study in 2003 ) which affect the serotonergic system and inhibit serotonin re-uptake. It also inhibits the breakdown of cortisol. I believe its actions are more in the nature of a balancing and normalizing; as many herbs have this quality (of adjusting either 'too much' or 'too little' by its own innate intelligence.). But enough of the chemistry; I can tell you this:
I have the luxury of myself to experiment on. I was in the full throes of a chronic period which had lasted 11 months with abatement of maybe a week or so at most every so often. Lately it had been roughly 4-6 episodes a day, several times a night as well. Usual durations were short, 15 min. to an hour; but several times I had the 24 hour marathons with short breaks. I am sure just about all of you know exactly what I was going through.
One standard dose of licorice root tincture aborted the cluster, and I have been PF since.
This stuff goes right to where the demon lives. I would be happy to discuss the particulars with anyone interested via email vis a vis causality;... but for our purposes here, let me just say this: I cannot and will not give anyone medical advice, but I can tell you what I did and why. I am casting it out there freely in the hope that someone may find the relief I did.
Here goes:
1. Not all licorice preparations are created equal. DO get the highest quality tincture you can find. It will cost you no more than about $20 for two ounces, which should last quite a while. I know thats small change to imitrex users.  I make my own and it is highly potent; you want a 1:5 tincture 40% alcohol by volume (don't worry the dose is so small the alcohol won't trigger you).
2. Use tincture, not tea or pills or extracts or anything other than a whole plant product.(Not all of the actives extract in water, and whole plant products are vastly superior to any extracts. Trust me, or read up on it. You'll see.)
3. I take a fairly standard dose of about 2 milliliters (about thirty drops) in a small amount of water 3 times a day. I plan on reducing the dose further, and then stopping it altogether and seeing if it works as an abortive. Like I said, its good to have yourself as a guinea pig.
4. I augment the licorice root with skullcap tincture, a sedative nervine herb which is very gentle, does not have any unpleasant effects and is superlative at relieving stress and nervous exhaustion. Dosage is the same as for the licorice root, 2 ml. three times daily. I find they complement each other as both will elevate your mood markedly (the serotonin thing again) which can't hurt, right?
5. Be aware that licorice root gets a bad rap from some folks who cite studies that it can cause potassium imbalances, sodium retention etc.; but what they don't tell you is that a) this occurs only after protracted use of a month to six weeks b) it by no means affects everyone who takes it c)the doses involved were at least four times greater than recommended daily amounts. Also, they used extract, and the whole plant contains compounds that ameliorate these effects.
6. I would be happy to answer any questions that I could if anyone wishes to email me.
7. You can see the serotonin study for yourself: just google licorice root.
This site is a blessing. I wish it was around when I was younger, but its enough that its here now. Be well.
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Potter
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Re: an herbal option that works
Reply #1 - Dec 14th, 2010 at 11:55pm
 
Would red twizzlers work?

                Potter
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Re: an herbal option that works
Reply #2 - Dec 15th, 2010 at 1:04am
 
Linda, I did not find he was selling, just describing.  I looked for that also.

I have no idea if it works or not.  I'm going to have to do some homework before trying it.

Jerry
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Re: an herbal option that works
Reply #3 - Dec 15th, 2010 at 1:08am
 
Hey Igenser,

Glad to see you've been getting relief.

It will be interesting to see what happens if other clusterheads try your approach, as I figure it would help rule out any coincidence factor with your CH stopping at the same time that you started the licorice tincture.

I didn't realize that about the herbal tinctures having the "whole plant" advantage. Going a bit off topic for a sec here, but what do you think about herbal teas in general - do they involve  too much heat, killing the active compounds, or are they still useful?

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« Last Edit: Dec 15th, 2010 at 1:50am by bejeeber »  

CH according to Bejeeber:

Strictly relying on doctors for CH treatment is often a prescription that will keep you in a whole lot of PAIN. Doctors are WAY behind in many respects, and they are usually completely unaware of the benefits of high flow 100% O2.

There are lots of effective treatments documented at this site. Take matters into your own hands, learn as much as you can here and at clusterbusters.com, put it into practice, then tell this CH beast Jeebs said hello right before you bash him so hard with a swift uppercut knockout punch that his stupid horns go flinging right off.
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Re: an herbal option that works
Reply #4 - Dec 15th, 2010 at 6:40am
 
Potter wrote on Dec 14th, 2010 at 11:55pm:
Would red twizzlers work?

                Potter

Twizzlers make mouths Happy!   Cheesy
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wimsey1
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Re: an herbal option that works
Reply #5 - Dec 15th, 2010 at 7:50am
 
I have heard the virtues of licorice root extolled before, but whatever connection there may between black licorice and licorice root...I know I, and others, have linked licorice as a fairly consistent trigger. Also, I remember there being evidence that a CH was preceded by a serotonin storm, which is a bad thing, and wonder if increasing sorotonin would be a good thing for CHs. Having taken GABA in the past and finding it worsened the cycle, I have my doubts. But then again, I could be mixing up all sorts of homeopathic errors here. Time to exit. lance
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Re: an herbal option that works
Reply #6 - Dec 15th, 2010 at 8:31am
 
Licorice root can raise the blood pressure.
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Re: an herbal option that works
Reply #7 - Dec 15th, 2010 at 10:45am
 
wimsey1 wrote on Dec 15th, 2010 at 7:50am:
I have heard the virtues of licorice root extolled before, but whatever connection there may between black licorice and licorice root...I know I, and others, have linked licorice as a fairly consistent trigger. Also, I remember there being evidence that a CH was preceded by a serotonin storm, which is a bad thing, and wonder if increasing sorotonin would be a good thing for CHs. Having taken GABA in the past and finding it worsened the cycle, I have my doubts. But then again, I could be mixing up all sorts of homeopathic errors here. Time to exit. lance

Actually, from what I'm reading this stuff acts like a serotonin re-uptake inhibitor, which can be effective in threating CH.  I would be cautious taking it in conjunction with any anti-depressants or 5HTP (which some people here use).  I think it could work............
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Re: an herbal option that works
Reply #8 - Dec 15th, 2010 at 1:01pm
 
Since it may be connected to serotonin levels, you never know.

When mushrooms were first suggested on here years ago, a bloodbath ensued. Now look at it.

I hope someone else DOES try it. I would be interested to hear how it worked.
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Re: an herbal option that works
Reply #9 - Dec 15th, 2010 at 1:32pm
 
1. I'm not selling anything. I thought I made that very clear. I also thought I made clear that I have suffered CH for 37 years and counting. I apologize if anyone had trouble following; I am certainly not trying for any literary prizes here.  I also did not intend to post twice. As I might have mentioned, I have not been near a computer in years. Sorry.
2. "black licorice", most licorice candy in fact contains no licorice at all, rather it contains anise. Licorice root is quite different.
3. "Serotonin storm" is an apt term but what is not understood by ANYONE is whether that means excessive production of serotonin, depletion and uptake of serotonin, or some other mechanism. I think the most apt metaphor would be to think of it as a short circuiting of normal circadian process in the hypothalamus resulting in wildly fluctuating imbalance.As I said, this particular herb is a genius at balancing. Consider this; You are probably familiar with the ability of psylocibin to abort clusters almost instantly. Psylocibin metabolizes as psylocin, an indole which is virtually structurally identical to serotonin. It is presumed that the psylocin replaces serotonin on receptor sites; hence my hypothesis that preventing serotonin uptake would be a good thing. Also. since cortisol has been shown to be depleted in clusters, the ability of licorice root to inhibit the breakdown of cortisol and balance other adrenals seems important.
4. The off topic question: herbal teas and decoctions in water can be extremely effective; it all depends on the specific herb. For example, milk thistle (which is a miracle in itself) is widely marketed as a tea but it is useless therapeutically since sylimarin, the active ingredient in the herb, is soluble in alcohol but not water. Don't trust the clerk in the GNC or whatever to know any more than you do. They ARE trying to sell stuff.
5. CORRECT: Do not take licorice root with MAO inhibitors or some other antidepressants, or if you are medicated for hypertension, or if you suffer from osteoporosis, kidney disease, or if you are pregnant. As I tried to be clear about, I'm trying to discuss an herb not dispense medical advice. Always check with your Doctor. Of course, the odds are extremely high that your Doctor will know next to nothing about herbs. Or, for that matter, how most of the pharms they prescribe actually work. I will tell you this: Licorice root is a far more efficient serotonin reuptake inhibitor than any MAO inhibitor on the market today, has virtually no deleterious effects when taken at proper levels, no side effects to speak of, and can be stopped instantly without titreing down. And its cheap. Please don't take my word for ANY of this information: Do the research.
6. The other off topic question: Whole plant herbal products are always superior to "Scientifically" produced extracts. Does anyone really think we can improve on millions of years of evolution? (sorry creationists). Example: Garlic. This plant is a proven and reliable antiviral and antibacterial agent. It will stop respiratory infections, colds, flu, even kills (documented) antibiotic resistant pneumonia. It is also available, cheap, in the supermarket. This annoys the crap out of makers of "natural" products.  Garlic is a chemical slurry of about 35-50 active compounds, all working synergistically. How do we know which ones are necessary? Put up with the bad breath and take the whole herb. "Extracts" and their lack of effectiveness have given many viable herbal remedies a bad name.
7. I assume you are joking, but no twizzlers will not work. As I said, licorice candy generally contains no licorice at all.
8. This part is serious: In answer, I think to another good point raised, the tincture did NOT terminate the cluster, so I am relatively sure the results I'm getting are not coincidental with it just spontaneously ending. This is what is happening now: I am still experiencing the 'metabolic' disturbances; I have been waking up at what are the usual intervals with the flushing, hot flashes and other peripherals that generally would have me up and going for the ice packs. I have had this happen only once during waking hours.... But what is different is that these disturbances do NOT escalate or lead to any significant pain. I have just kind of noted them (and to really feel whats going on in the triggering process has been very valuable) and after a few minutes they fade and I have gone back to sleep. I guess what I am trying to say is that I believe the cluster is still with me; it just doesn't hurt, if that makes any sense.
9. I briefly looked at some of the posts on the boards last night; as I said I have had these f-ing things since I was 20 years old. I went through the years of misdiagnosis, the youthful fears I was dying of brain tumors, the condescension of doctors, the fear of going anywhere or doing anything and the shame of "ruining" occasions with an unpredictable invisible illness I had no control over. I have been to the same places you all have, and my heart goes out to all of you.
I am not at all invested in whether anyone follows my suggestions or not. I have very rarely accepted any money for any of the things I have made for people or animals; I consider it part of my karmic obligation.
I am invested in stopping the pain, primarily my own. I'm quite certain you all know why. If it helps anyone else, I will be very happy.
I'll check back at some point later if I can answer any other questions. Thank you for being here.
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Re: an herbal option that works
Reply #10 - Dec 15th, 2010 at 2:21pm
 
lgenser wrote on Dec 15th, 2010 at 1:32pm:
9. I briefly looked at some of the posts on the boards last night; as I said I have had these f-ing things since I was 20 years old. I went through the years of misdiagnosis, the youthful fears I was dying of brain tumors, the condescension of doctors, the fear of going anywhere or doing anything and the shame of "ruining" occasions with an unpredictable invisible illness I had no control over. I have been to the same places you all have, and my heart goes out to all of you.
I am not at all invested in whether anyone follows my suggestions or not. I have very rarely accepted any money for any of the things I have made for people or animals; I consider it part of my karmic obligation.
I am invested in stopping the pain, primarily my own. I'm quite certain you all know why. If it helps anyone else, I will be very happy.
I'll check back at some point later if I can answer any other questions. Thank you for being here.

+1 Spoken like a true CH'er.  Couldn't agree more and thanks for sharing the information with us.
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Triptans cause increased number of hits and increased intensity.  Learn it, believe it, live it.  I use triptans as the absolute LAST RESORT when treating my CH.&&
 
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Re: an herbal option that works
Reply #11 - Dec 15th, 2010 at 2:27pm
 
Man I'm starting to get a hankering for some licorice tincture!  Grin

I have read about the wide health benefits of licorice root before, and I certainly love the flavor of Yogi brand Egyptian licorice tea.    Cool

I think I've seen some tinctures on the market before that are alcohol free - would be nice if there is a  high quality licorice root one, since so many many of us clusterheads (including myself) have become so deathly afraid of even a hint of the booze.

I also remember someone saying once that if you leave your tincture dose in an open cup for half an hour the alcohol will evaporate off? Hmm maybe that was for putting tincture in a tea or something...
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CH according to Bejeeber:

Strictly relying on doctors for CH treatment is often a prescription that will keep you in a whole lot of PAIN. Doctors are WAY behind in many respects, and they are usually completely unaware of the benefits of high flow 100% O2.

There are lots of effective treatments documented at this site. Take matters into your own hands, learn as much as you can here and at clusterbusters.com, put it into practice, then tell this CH beast Jeebs said hello right before you bash him so hard with a swift uppercut knockout punch that his stupid horns go flinging right off.
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Re: an herbal option that works
Reply #12 - Dec 15th, 2010 at 2:34pm
 
Another something to try.
bb
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bejeeber
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Re: an herbal option that works
Reply #13 - Dec 15th, 2010 at 3:10pm
 
lgenser wrote on Dec 15th, 2010 at 1:32pm:
....I believe the cluster is still with me; it just doesn't hurt, if that makes any sense....



Certainly not the first time I've heard that - from what I remember, it's a fairly commonly reported experience over at the clusterbusters.com forum amongst CH'ers who have busted with psilocybin.
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CH according to Bejeeber:

Strictly relying on doctors for CH treatment is often a prescription that will keep you in a whole lot of PAIN. Doctors are WAY behind in many respects, and they are usually completely unaware of the benefits of high flow 100% O2.

There are lots of effective treatments documented at this site. Take matters into your own hands, learn as much as you can here and at clusterbusters.com, put it into practice, then tell this CH beast Jeebs said hello right before you bash him so hard with a swift uppercut knockout punch that his stupid horns go flinging right off.
bejeeber bejeeber Enter your address line 1 here  
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Re: an herbal option that works
Reply #14 - Dec 16th, 2010 at 8:01am
 
Quote:
I am not at all invested in whether anyone follows my suggestions or not. I have very rarely accepted any money for any of the things I have made for people or animals; I consider it part of my karmic obligation.
I am invested in stopping the pain, primarily my own. I'm quite certain you all know why. If it helps anyone else, I will be very happy.
I'll check back at some point later if I can answer any other questions. Thank you for being here.


You seem to have missed that we are interested. For the most part your posting is intelligent and forthright; it is a tad defensive, perhaps because we have seen so many who were selling something. That you "seldom" take money for what you make is not the same thing as I am not selling anything. I am sure you are only interested in something that may help and is not in our current regimen. I do hope you find a way to keep this going, with research and personal anecdote. Hang in there and you'll find this is a strong community of support. Blessings...sorry karmic types  Wink  lance
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Re: an herbal option that works
Reply #15 - Dec 16th, 2010 at 2:29pm
 
Excessive consumption of liquorice or liquorice candy is known to be toxic to the liver[20] and cardiovascular system, and may produce hypertension [21] and oedema.[22] In occasional cases blood pressure has increased with excessive consumption of liquorice tea, but such occasions are rare and reversible when the herb is withdrawn.[23] Most cases of hypertension from liquorice were caused by eating too much concentrated liquorice candy.[24] Doses as low as 50 grams (2 oz) of liquorice daily for two weeks can cause a significant rise in blood pressure.[25]

The European Commission 2008 report suggested that “people should not consume any more than 100mg of glycyrrhizic acid a day, for it can raise blood pressure or cause muscle weakness, chronic fatigue, headaches or swelling, and lower testosterone levels in men.”

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Re: an herbal option that works
Reply #16 - Dec 16th, 2010 at 8:45pm
 
In response to the points made in reply #15:
the dosages referred to reported as dangerous are far, far in excess of what has so far (knock wood) been an extremely effective therapeutic dose: 6 milliliters per day, spaced into three doses. That is roughly one tablespoon.
I have no doubt that in the quantities you describe it would be nasty for the liver to process, but Japanese studies have shown (at proper dosage levels) that the antihepatotoxin activity of licorice root has shown benefits in patients with active hepatitis C. That is what I actually originally got interested in it for (for a friend).
Please bear in mind I am talking about the whole root extract, the tincture, not candy or tea.
Studies I can refer anyone to also indicate that the glycyrrhizin (which is the principal culprit cited in most of the negative effects) is "less bioavailable and has less toxicity when given in a whole extract rather than as an isolated substance". Licorice preparations are available with the glycyrrhizin removed, they are called 'DGL', but this may "reduce some of the herb's activity". Tinctures are also available with the alcohol removed (they are called glycerates), but I am extremely sensitive to alcohol,  it triggers me in minutes,  and I have never had an adverse reaction. Again, probably because the dose is so small and licorice tincture is relatively low alcohol (40%).
In any case; over a week into my personal experiment here I have had exactly one 'quasi' headache after a full day of intentional exposure to environmental triggers, it literally lasted less than ten minutes, wasn't particularly painful as these things go and was gone before I could really get the ice packs out ( I wasn't being an optimist) with no recurrence since. I am still experiencing, at intervals, the middle of the night 'metabolic' disturbances; kind of like hot flashes but they fade after a few minutes. I can report no adverse effects as of yet.
Please be reassured I will be just as quick to report negatives. I have been disappointed before; I am quite certain that is a familiar sentiment around here.
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Re: an herbal option that works
Reply #17 - Dec 23rd, 2010 at 10:26am
 
julyn wrote on Dec 16th, 2010 at 2:29pm:
Excessive consumption of liquorice or liquorice candy is known to be toxic to the liver[20] and cardiovascular system, and may produce hypertension [21] and oedema.[22] In occasional cases blood pressure has increased with excessive consumption of liquorice tea, but such occasions are rare and reversible when the herb is withdrawn.[23] Most cases of hypertension from liquorice were caused by eating too much concentrated liquorice candy.[24] Doses as low as 50 grams (2 oz) of liquorice daily for two weeks can cause a significant rise in blood pressure.[25]

The European Commission 2008 report suggested that “people should not consume any more than 100mg of glycyrrhizic acid a day, for it can raise blood pressure or cause muscle weakness, chronic fatigue, headaches or swelling, and lower testosterone levels in men.”

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Imitrex can cause immediate death...........

Quote:
Serious cardiac events, including some that have been fatal, have occurred following the use of Imitrex Injection or Tablets. These events are extremely rare and most have been reported in patients with risk factors predictive of CAD. Events reported have included coronary artery vasospasm, transient myocardial ischemia, myocardial infarction, ventricular tachycardia, and ventricular fibrillation.

Significant hypertensive episodes, including hypertensive crises, have been reported on rare occasions in patients with or without a history of hypertension.

And people endorse this stuff here all the time.
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« Last Edit: Dec 23rd, 2010 at 10:29am by Agostino Leyre »  

Triptans cause increased number of hits and increased intensity.  Learn it, believe it, live it.  I use triptans as the absolute LAST RESORT when treating my CH.&&
 
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Re: an herbal option that works
Reply #18 - Dec 26th, 2010 at 1:49pm
 
I thank you for your post.

I also intend to do a little homework on licorice root and it's effects.  I truly hope this works, not only for you, but for many for clusterheads.  As someone else said above, who knew shrooms and seeds would be a Godsend to sufferers.

I will count nothing out.

Please keep posting as to your results.

Sandy
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Re: an herbal option that works
Reply #19 - Feb 26th, 2011 at 3:52pm
 
Thank you for that post lgenser.

If I had read this thread a week ago, I would certainly have tried it.  So I bump this one.

For now, I'm fighting the thing with the clusterbuster, high dose of vit.D3 (after reading Batch's post) and Tongkat ali which is suppose to increase testosterone levels.  Adding to the mix 9mg of melatonin at bed time and I'm doing quite well.

PFDAN to all

edit: added (after reading Batch's post)
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« Last Edit: Feb 26th, 2011 at 4:19pm by bluesunshine »  
 
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Re: an herbal option that works
Reply #20 - Feb 26th, 2011 at 6:26pm
 
Hi,
If anyone wants a volunteer, just tell me where to get it, how much to take and we'll see what happens. The Ancients had to cope with this shit too, without Veramapril and O2!

Respect igenser!
You look as if you have done your research! My mind is open, my CH is a 'shadow' (forgive the pun here) of what it was 11 yrs ago..If you had said to me when the Kip 3 hits my left temple 'go rub some 'Vicks' on it (Vapour rub)..I would have told to you to go and ********I mean, take a hike! However, it does work (for me) but only coming in and going out of cycle...

Its got to be worth a try as this rubber band on my JT is doing nothing for the clusters..
(the swelling is however, coming along quite nicely thank you!)  Cheesy

Respect and wink  Wink

Gary
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« Last Edit: Feb 27th, 2011 at 12:05pm by Batty »  

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Re: an herbal option that works
Reply #21 - Jun 9th, 2013 at 1:56am
 
I see no replies on this one for a while so excuse me commenting on such an old thread.

Is there something wrong with the search or is there simply no discussion about Liquorice root protocol ? I searched with "liqorice" and "liquorice" and came up with nothing.

I am a bit astonished to say at least. I have been using liquorice root (with skull cap as adviced) ever since Les Genser shared this protocol and have quite a few fellow finns who have had success with it as well. I just came to this board and thought it would be a subject lot talked about. But not much talk or maybe I just can't find it ?

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Hoppy
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LAUGHTER IS THE BEST MEDICINE


Posts: 1890
Perth WA
Gender: male
Re: an herbal option that works
Reply #22 - Jun 9th, 2013 at 3:10am
 
Hi Tony,
Not wanting to sound to dumb, but what is Liquorice Root
( with skull cap )  Questioning


Hoppy.
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Tony Only
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Ain't Life Grand


Posts: 43
Re: an herbal option that works
Reply #23 - Jun 9th, 2013 at 4:33am
 
Does not sound dumb at all, I certainly had never heard of them before Les published his protocol. You can find it at our finnish CH site for an example.

EDIT: It seems I can not post links before I have 10 posts so just copy this to your address bar:
sites.google.com/site/hortoninneuralgia/resurssit/englanti/liquorice-root-protoc
ol
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Mike NZ
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Oxygen rocks! D3 too!


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Auckland, New Zealand
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Re: an herbal option that works
Reply #24 - Jun 9th, 2013 at 5:30pm
 
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