I have found an article on Nitric Oxide...

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Posted by Riccardo ( on April 19, 2000 at 07:22:50:

...in italian...:-) I have translated it (quicky, sorry!) for you.
It is interesting, take a look: the nitric oxide comes from burning devices, car engines, pollution, etc...all things that are triggers for us.

The nitric oxide [NO] has retained one of most important mediators of the inflammation in varied illness today, from the dermatomiositys to the migraine, from the septic shock to the systemic progressive sclerosys. He is in fact recognized as a mediator in all the organism and already in the migraine his role has resulted important for meds that,in the phase of beginning of the crisis, reduces the NO production and stop the attack.
A review, recently published from a group of researchers of the Department of Clinical Medicine of the University from Rome "La Sapienza" coordinated from the Dr. Paolo Martelletti, on the authoritative magazine scientific EOS Journal Immunology Immunopharmacology , propose the nitric oxide [NO] like fundamental substance in the start of the deadly crisis of cluster headaches. It in fact, has resulted involved in the activation of the brain trunk and of the cerebral vessels, therefore in both the retained situations involved in this illness.
The application of meds that reduce the production of the nitric oxide will represent an useful therapeutic relief for the patients that suffer of this rare but violent form of headache.

EOS J Immunol Immunopharmacol 1999;19;19-22

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