Ihatech,
Your husband needs to start the vitamin D3 loading schedule. This dosing schedule calls for 600,000 IU of vitamin D3 over a 4-week period... Yes, I know that sounds like a lot but it averages out to a little over 20,000 IU/day.
The key part of this loading schedule is it's front loaded with higher doses to elevate your husbands 25(OH)D serum concentration a lot faster and that should translate to a favorable response in less time.
He needs to start this loading schedule with two weeks at 20,000 IU/day vitamin D3. In addition, he needs to take a 50,000 IU loading dose of vitamin D3 on top of the daily 20,000 IU vitamin D3 once a week during the first two weeks. For the next two weeks he can lower the vitamin D3 dose to 15,000 IU/day. He also needs to take all the other supplements and doses listed in the anti-inflammatory regimen table below.
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The following photo illustrates the supplements by brand that I take to get the required doses listed in the table above.
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At the end of the 4-week loading schedule, your husband needs to see his PCP for another 25(OH)D lab test. If this loading schedule works for your husband like it has for many other CH'ers, his 25(OH)D response should average 60 ng/mL on top of his starting serum concentration...
In other words, his 25(OH)D serum concentration should be around 84 ng/mL at the end of the loading schedule.
Again this is a very safe vitamin D3 loading schedule. I have a study where 600,000 IU of vitamin D3 was given in a single oral dose to 43 adults with no evidence of hypercalciuria, hypercalcemia, parathyroid dysfunction or radiological evidence of calcification.
There's a second Phase I/II Safety trial where 25 multiple sclerosis patients were put on an escalating vitamin D3 dosing schedule for one year that reached a maximum dose of 40,000 IU/day vitamin D3 for six weeks before dropping back down to 10,000 IU/day. Again, no problems... Their RRMS got a lot better.
Regarding botox injections... Botulism Toxin... It will kill any and every cell it comes in contact with and these cells will never be replaced.
We all come with a very functional set of nerve cells that serve a number of essential functions... Killing some of these nerve cells to stop a pain is a bad move when all you need to do is give these cells the nutrients they need and they'll heal themselves.
Sorry... I didn't mean to get up on the soap box... I just find it hard to believe that big pharma makes a killing in the pharmaceutical market space selling a very toxic poison... after talking physicians into using it... I may be old school, but that sure throws "Do no harm" under the bus...
Take care, hang in there and please keep us posted.
V/R, Batch